(n.) The heart or inner part of a thing, as of a column, wall, rope, of a boil, etc.; especially, the central part of fruit, containing the kernels or seeds; as, the core of an apple or quince.
(n.) The center or inner part, as of an open space; as, the core of a square.
(n.) The most important part of a thing; the essence; as, the core of a subject.
(n.) The prtion of a mold which shapes the interior of a cylinder, tube, or other hollow casting, or which makes a hole in or through a casting; a part of the mold, made separate from and inserted in it, for shaping some part of the casting, the form of which is not determined by that of the pattern.
(n.) A disorder of sheep occasioned by worms in the liver.
(n.) The bony process which forms the central axis of the horns in many animals.
(v. t.) To take out the core or inward parts of; as, to core an apple.
(v. t.) To form by means of a core, as a hole in a casting.
Example Sentences:
(1) Even with hepatic lipase, phospholipid hydrolysis could not deplete VLDL and IDL of sufficient phospholipid molecules to account for the loss of surface phospholipid that accompanies triacylglycerol hydrolysis and decreasing core volume as LDL is formed (or for conversion of HDL2 to HDL3).
(2) Hoursoglou thinks a shortage of skilled people with a good grounding in core subjects such as maths and science is a potential problem for all manufacturers.
(3) Schneiderlin, valued at an improbable £27m, and the currently injured Jay Rodriguez are wanted by their former manager Mauricio Pochettino at Spurs, but the chairman Ralph Krueger has apparently called a halt to any more outgoings, saying: “They are part of the core that we have decided to keep at Southampton.” He added: “Jay Rodriguez and Morgan Schneiderlin are not for sale and they will be a part of our club as we enter the new season.” The new manager Ronald Koeman has begun rebuilding by bringing in Dusan Tadic and Graziano Pellè from the Dutch league and Krueger said: “We will have players coming in, we will make transfers to strengthen the squad.
(4) Core biopsy with computed tomography (CT) or ultrasound (US) guidance may be such an alternative, particularly when a spring-loaded firing device is used.
(5) Core enzyme, lacking omega subunit, catalyzed this reaction at a rate less than 1% that of holoenzyme.
(6) The specified region of the inner E2 core domain was highly homologous to the region of the E2 subunit of pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase.
(7) Each species has approximately 500 core histones cluster repeats per haploid genome.
(8) Thus there may be four types of LPS in PACI: one contains unsubstituted core polysaccharide and yields L2 on acid hydrolysis, another has short antigenic side-chains of the SR type and yields the LI fraction, while the two high molecular weight fractions are derived from core polysaccharides with different side-chains.
(9) Peptidoglycan synthesis is unaffected by the mutations affecting the core glycosyltransferases.
(10) The common atoms of the [3Fe-4S] and [4Fe-4S] cores agree within 0.1 A; the three common cysteinyl S gamma ligand atoms agree within 0.25 A.
(11) Tachycardia, pulmonary hypertension, increased venous oxygen desaturation, and increasing core temperature develop as the syndrome progresses.
(12) Some aspects of the life structure, of course, are also unconscious, namely, those having to do with attempted solutions to core personality conflicts and those reflecting modes of ego functioning.
(13) The interaction was specific for the DNA-binding activity of receptor, since H1 histones inhibit neither T3-binding activity nor core histone-binding activity of receptor.
(14) In contrast to the defect in another packaging-deficient mutant ts1201, the block in the formation of dense-cored, DNA-containing capsids in ts1233-infected cells at the NPT could not be reversed by transferring the cells to the permissive temperature in the presence of a protein synthesis inhibitor.
(15) Steady state levels of chloroplast mRNA encoding the core PSII polypeptides remain nearly constant in the light or the dark and are not affected by the developmental stage of the plastid.
(16) Viral particles in the cultures and the brain were of various sizes and shapes; particles ranged from 70 to over 160 nm in diameter, with a variable position of dense nucleoids and less dense core shells.
(17) The ternary complex consisting of a 65-kDa peptide originating from the proteoglycan core protein and a 43-kDa link protein bound to hyaluronic acid was purified from a clostripain digest of the rat chondrosarcoma aggregating proteoglycan and 14C-carbamylated with potassium [14C]cyanate.
(18) The binding of 125I-labeled core protein to immobilized fibronectin was inhibited by soluble fibronectin and by soluble cold core protein but not by albumin or gelatin.
(19) Intact wild-type cells, or those of a mutant in which the core region of the lipopolysaccharide was absent, were equally resistant to pronase treatment.
(20) The others had the structures galactosyl-galactosyl-xylosyl-4-methylumbelliferone and galactosyl-xylosyl-4-methylumbelliferone, respectively, representing the linkage region between the glycosaminoglycan chains and core protein, except that 4-methylumbelliferone replaced the amino acid.
Iron
Definition:
(n.) The most common and most useful metallic element, being of almost universal occurrence, usually in the form of an oxide (as hematite, magnetite, etc.), or a hydrous oxide (as limonite, turgite, etc.). It is reduced on an enormous scale in three principal forms; viz., cast iron, steel, and wrought iron. Iron usually appears dark brown, from oxidation or impurity, but when pure, or on a fresh surface, is a gray or white metal. It is easily oxidized (rusted) by moisture, and is attacked by many corrosive agents. Symbol Fe (Latin Ferrum). Atomic weight 55.9. Specific gravity, pure iron, 7.86; cast iron, 7.1. In magnetic properties, it is superior to all other substances.
(n.) An instrument or utensil made of iron; -- chiefly in composition; as, a flatiron, a smoothing iron, etc.
(n.) Fetters; chains; handcuffs; manacles.
(n.) Strength; power; firmness; inflexibility; as, to rule with a rod of iron.
(n.) Of, or made of iron; consisting of iron; as, an iron bar, dust.
(n.) Resembling iron in color; as, iron blackness.
(n.) Like iron in hardness, strength, impenetrability, power of endurance, insensibility, etc.;
(n.) Rude; hard; harsh; severe.
(n.) Firm; robust; enduring; as, an iron constitution.
(n.) Inflexible; unrelenting; as, an iron will.
(n.) Not to be broken; holding or binding fast; tenacious.
(v. t.) To smooth with an instrument of iron; especially, to smooth, as cloth, with a heated flatiron; -- sometimes used with out.
(v. t.) To shackle with irons; to fetter or handcuff.
(v. t.) To furnish or arm with iron; as, to iron a wagon.
Example Sentences:
(1) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(2) The most successful dyes were phenocyanin TC, gallein, fluorone black, alizarin cyanin BB and alizarin blue S. Celestin blue B with an iron mordant is quite successful if properly handled to prevent gelling of solutions.
(3) These membrane perturbation effects not observed with bleomycin-iron in the presence of a hydroxyl radical scavenger, dimethyl thiourea, or a chelating agent, desferrioxamine, were correlated with the ability of the complex to generate highly reactive oxygen species.
(4) The specific activities of extracts from cells grown under phototrophic and aerobic conditions were similar and not affected by the concentration of iron in the growth media.
(5) In the 153 women to whom iron supplements were given during pregnancy, the initial fall in haemoglobin concentration was less, was arrested by 28 weeks gestation and then rose to a level equivalent to the booking level.
(6) Typically the iron-iron axis (gz) of the binuclear iron-sulfur clusters is in the membrane plane.
(7) Increased iron levels in basal ganglia were generally associated with normal or elevated levels of ferritin immunoreactivity, for example, the substantia nigra in PSP and possibly MSA, and in putamen in MSA.
(8) Lead levels in contents and shells of eggs laid by hens dosed with all-lead shot were about twice those in eggs laid by hens dosed with lead-iron shot.
(9) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
(10) Since iron from fortified formulas is well absorbed during the first three months of life, even if it is not immediately used for hemoglobin formation, an inccrease in the iron stores will occur...
(11) Dietary intakes, measured by three 24-hour recalls, revealed that protein, iron and Vitamin C generally met or exceeded the Nutrition Recommendations for age.
(12) This is a struggle for the survival of our nation.” As ever, after Trump’s media dressing-down, his operation was quick to fit a velvet glove to an iron fist.
(13) Ten weeks of iron therapy was not, however, long enough to increase iron stores.
(14) With both approaches, carbohydrate and fat had little influence whereas egg albumin had a significant inhibitory effect on the absorption of nonheme iron.
(15) The protein quality and iron bioavailability of mechanically deboned turkey meat (MDT) and hand-deboned turkey meat (HDT) were determined in rats.
(16) Serum levels of vitamins A and E, zinc and iron were determined in healthy control subjects and lepromatous leprosy patients belonging to an eastern state of India.
(17) Ferric iron in aqueous solution was used as an iron-only control.
(18) The implications of inhibition of protein kinase C by adriamycin-iron(III) are discussed.
(19) The duodenal mucosa of genotypically normal iron replete and iron deficient mice and mice with sex-linked (sla) and microcytic anemias (mk) was examined for the presence of iron-binding proteins.
(20) Ferredoxin reductase (Fd-reductase) supplies reducing equivalents obtained from NADPH to mitochondrial cytochrome P450 enzymes via the small iron-sulfur protein ferredoxin.