(n.) The heart or inner part of a thing, as of a column, wall, rope, of a boil, etc.; especially, the central part of fruit, containing the kernels or seeds; as, the core of an apple or quince.
(n.) The center or inner part, as of an open space; as, the core of a square.
(n.) The most important part of a thing; the essence; as, the core of a subject.
(n.) The prtion of a mold which shapes the interior of a cylinder, tube, or other hollow casting, or which makes a hole in or through a casting; a part of the mold, made separate from and inserted in it, for shaping some part of the casting, the form of which is not determined by that of the pattern.
(n.) A disorder of sheep occasioned by worms in the liver.
(n.) The bony process which forms the central axis of the horns in many animals.
(v. t.) To take out the core or inward parts of; as, to core an apple.
(v. t.) To form by means of a core, as a hole in a casting.
Example Sentences:
(1) Even with hepatic lipase, phospholipid hydrolysis could not deplete VLDL and IDL of sufficient phospholipid molecules to account for the loss of surface phospholipid that accompanies triacylglycerol hydrolysis and decreasing core volume as LDL is formed (or for conversion of HDL2 to HDL3).
(2) Hoursoglou thinks a shortage of skilled people with a good grounding in core subjects such as maths and science is a potential problem for all manufacturers.
(3) Schneiderlin, valued at an improbable £27m, and the currently injured Jay Rodriguez are wanted by their former manager Mauricio Pochettino at Spurs, but the chairman Ralph Krueger has apparently called a halt to any more outgoings, saying: “They are part of the core that we have decided to keep at Southampton.” He added: “Jay Rodriguez and Morgan Schneiderlin are not for sale and they will be a part of our club as we enter the new season.” The new manager Ronald Koeman has begun rebuilding by bringing in Dusan Tadic and Graziano Pellè from the Dutch league and Krueger said: “We will have players coming in, we will make transfers to strengthen the squad.
(4) Core biopsy with computed tomography (CT) or ultrasound (US) guidance may be such an alternative, particularly when a spring-loaded firing device is used.
(5) Core enzyme, lacking omega subunit, catalyzed this reaction at a rate less than 1% that of holoenzyme.
(6) The specified region of the inner E2 core domain was highly homologous to the region of the E2 subunit of pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase.
(7) Each species has approximately 500 core histones cluster repeats per haploid genome.
(8) Thus there may be four types of LPS in PACI: one contains unsubstituted core polysaccharide and yields L2 on acid hydrolysis, another has short antigenic side-chains of the SR type and yields the LI fraction, while the two high molecular weight fractions are derived from core polysaccharides with different side-chains.
(9) Peptidoglycan synthesis is unaffected by the mutations affecting the core glycosyltransferases.
(10) The common atoms of the [3Fe-4S] and [4Fe-4S] cores agree within 0.1 A; the three common cysteinyl S gamma ligand atoms agree within 0.25 A.
(11) Tachycardia, pulmonary hypertension, increased venous oxygen desaturation, and increasing core temperature develop as the syndrome progresses.
(12) Some aspects of the life structure, of course, are also unconscious, namely, those having to do with attempted solutions to core personality conflicts and those reflecting modes of ego functioning.
(13) The interaction was specific for the DNA-binding activity of receptor, since H1 histones inhibit neither T3-binding activity nor core histone-binding activity of receptor.
(14) In contrast to the defect in another packaging-deficient mutant ts1201, the block in the formation of dense-cored, DNA-containing capsids in ts1233-infected cells at the NPT could not be reversed by transferring the cells to the permissive temperature in the presence of a protein synthesis inhibitor.
(15) Steady state levels of chloroplast mRNA encoding the core PSII polypeptides remain nearly constant in the light or the dark and are not affected by the developmental stage of the plastid.
(16) Viral particles in the cultures and the brain were of various sizes and shapes; particles ranged from 70 to over 160 nm in diameter, with a variable position of dense nucleoids and less dense core shells.
(17) The ternary complex consisting of a 65-kDa peptide originating from the proteoglycan core protein and a 43-kDa link protein bound to hyaluronic acid was purified from a clostripain digest of the rat chondrosarcoma aggregating proteoglycan and 14C-carbamylated with potassium [14C]cyanate.
(18) The binding of 125I-labeled core protein to immobilized fibronectin was inhibited by soluble fibronectin and by soluble cold core protein but not by albumin or gelatin.
(19) Intact wild-type cells, or those of a mutant in which the core region of the lipopolysaccharide was absent, were equally resistant to pronase treatment.
(20) The others had the structures galactosyl-galactosyl-xylosyl-4-methylumbelliferone and galactosyl-xylosyl-4-methylumbelliferone, respectively, representing the linkage region between the glycosaminoglycan chains and core protein, except that 4-methylumbelliferone replaced the amino acid.
Nub
Definition:
(v. t.) To push; to nudge; also, to beckon.
(n.) A jag, or snag; a knob; a protuberance; also, the point or gist, as of a story.
Example Sentences:
(1) Out of the latter, NUB congenital defect was in 4, total epispadia in 1, spina bifida in 1 patient.
(2) In the case of S. enteritidis NUB 31, the effect of CPS-K was detectable only when more than 20 mug per mouse was injected.
(3) And that is the nub of the FT report: grim reading for chancellor George Osborne as he puts the finishing touches to his 19 March budget.
(4) The peak CPS-K effect on infection with S. enteritidis NUB 1 was seen when given immediately before bacterial challenge.
(5) Some wore "slave bracelets" made out of boot laces and walked with "Black Power canes", sticks with the nub carved into a clenched fist.
(6) This is the nub of the issue and the foreign secretary's statement seems to mask a much more complex picture.
(7) Four new nuB mutations in the DNA gyrase-binding site between the G and I genes were also sequenced and found to be identical to the nuB103 mutation sequenced previously.
(8) The nub of Zittrain’s concern is that the practice of shaping what stays and what goes from the database is hopelessly individualistic.
(9) The promotion of infection with S. enteritidis NUB 1 by CPS-K depended upon its dose, the effect of CPS-K being demonstrable up to as little as 0.2 mug per mouse.
(10) This is the nub of what I am going to call, because I've always secretly wanted to be a mathematician, the "Birmingham Liberty Paradox".
(11) And I'm hopeful that we're getting closer to the nub of the problem.
(12) The nub of the controversy was his comment that "we wouldn't have had all these problems over all these years" if Mr Thurmond, who ran a campaign to keep blacks out of white schools and neighbourhoods, had won the presidency in 1948.
(13) Both have seen very bleak scenarios depicted by either side in attempts to scare the electorate, for example with the idea that a yes vote will usher in a very authoritarian regime.” In his presentations, Baldini, who will vote yes, tries to go to what he sees as the nub of the issue.
(14) Our failing economy needs stimulating and your nub of grey meat and Mars egg are simply not sufficient.
(15) Why does it matter whether other people believe it or not?” I suspect that gets to the nub of it.
(16) As a result of enumeration of bacterial populations in the peritoneal washing, blood, liver and spleen, it was revealed that CPS-K promoted in vivo growth of S. enteritidis NUB 1 and NUB 31.
(17) The NUB-6 cell line consisted of two distinct cell subtypes, small typical neuroblasts and larger spheroid-forming cells, while NUB-7 was homogeneously neuroblastic.
(18) All the children were operated on: NUB reconstruction according to Davis, bilateral uretero-cystostomy according to Coen.
(19) Two new neuroblastoma (NB) cell lines, NUB-6 and NUB-7, were established from recurrent and primary NB tumours respectively and identified conclusively as NB by their phenotypic characteristics, catecholamine production and N-myc amplification.
(20) Urodynamic studies showed the absence of detrusor-sphincter dyssynergia and confirmed organic nature of NUB lesion.