What's the difference between cornea and keratome?
Cornea
Definition:
(n.) The transparent part of the coat of the eyeball which covers the iris and pupil and admits light to the interior. See Eye.
Example Sentences:
(1) Displacement of the surface of the cornea of bovine eyes after disruption of intact structures was investigated by means of holographic interferometry.
(2) The patient, a 12 year-old boy, showed a soft white yellowish mycotic excrescence with clear borders which had followed the introduction of a small piece of straw into the cornea.
(3) Increased amounts of laminin in the basal epithelium of the cornea and of collagen type III in the stroma and subepithelial components of the stroma were observed.
(4) We report on a membrane inflation method of wound spreading in intact human corneas using the Baribeau Micronscope.
(5) When 5 corneas with quiescent HSK were cultured in vitro, 3 again became HSV antigen positive.
(6) Corneas of bullfrog (Rana catesbeiana) were mounted between lucite chambers.
(7) The eye is of the closed vesicle type and is composed of retina, cornea, vitreous body, lens and optic nerve.
(8) The steps in the model are the drug elimination rate in the precornea and anterior chamber, the rate of drug dissolution, the rate of drug penetration into the cornea, and the rate of drug transport into the aqueous humor.
(9) Gas trapping and corneal edema were not observed in uncovered corneas or corneas covered with membrane lenses.
(10) Since lymphocytic cells in intimate contact with degenerating keratocytes have previously been identified in the cornea, these observations provide a basis for the view that cell-mediated immunopathogenesis is involved in the etiology of herpetic stromal keratitis.
(11) Lactate dehydrogenase (LDH) levels and subunit isozyme patterns in cornea were monitored in 36 albino rabbits wearing thick, rigid, gas-permeable contact lenses for periods of 24 h, 2 and 7 days, and 1 and 3 months.
(12) Calculations of energies of activation, taken from Arrhenius plots, indicate that the diffusion of drug across the cornea may be by two different mechanisms that depend on the physical-chemical characteristics of the perfusant.
(13) The mean in the newborn-to-6-month-old group was 47.59 D; in the 12-18-month-old group it had decreased to 45.56 D. The cornea appears to stabilize at about 54 months, with an average reading of 42.69 D. Evaluation of 11 eyes diagnosed as having persistent hyperplastic primary vitreous revealed that eyes with this diagnosis generally have steeper corneas than normal eyes at any given age.
(14) There was no significant difference in the wound-healing rate, but at 36 hours there was a reduction in wound-healing rate of the excimer ablated corneas.
(15) More importantly, this study reports the first detection of LAT in RNA extracted from 9% of corneas from latently infected rabbits (n = 22) by the polymerase chain reaction.
(16) Cat corneas were stored at refrigerator temperatures in M-K medium (TC-199, 5% dextran), modified M-K medium (TC-199, 1% chondroitin sulfate), or on the intact globe in moist chambers for intervals of one to nine days.
(17) Pterygia, triangular sheets of fibrovascular tissue that invade the cornea, have recurrence rates of 30% to 50% with currently available surgical procedures.
(18) Rabbit corneas grown in organ culture (24 well plate) were inoculated topically with 50 microliters (5 x 10(5) pfu) of different ocular adenoviral serotypes (ATCC and clinical isolates).
(19) A recipient cornea gradually developed wrinkling and opacification in Bowman's layer following an uneventful myopic epikeratoplasty.
(20) In neurological diseases the hyposensitivity could include the cornea, conjunctiva and lid margin.
Keratome
Definition:
(n.) An instrument for dividing the cornea in operations for cataract.
Example Sentences:
(1) Keratome biopsies were obtained from normal and psoriatic individuals.
(2) mRNA transcripts for the major mediator of GH actions, insulin-like growth factor 1 (IGF-1), were detected by PCR in fibroblasts, melanocytes, and keratome biopsies, but not in keratinocytes.
(3) Blot hybridization analysis of total RNA extracted from keratome biopsies revealed that RAR-gamma was the predominant RAR species expressed in human epidermis, as RAR-alpha transcripts were detectable only at low levels and RAR-beta transcripts were undetectable.
(4) Northern analysis, using the cloned GH-R as probe, revealed relatively higher levels of GH-R transcripts in cultured human dermal fibroblasts compared to cultured keratinocytes or keratome biopsies.
(5) Keratome slices of human or animal skin release enzymes, show histochemical changes and demonstrate increased or decreased utilization of isotope-labelled amino acids when exposed to chemicals, including surfactants, or bacterial toxins (Clostridium perfringens).
(6) Protein kinase C activity was purified 30-fold from high speed supernatants prepared from homogenates of keratome biopsies obtained from healthy volunteers.
(7) The examination of keratome slices of skin for release of enzymes, for changed histochemistry and for utilization of radioisotope-labelled amino acids will detect weak irritants but is of doubtful value for moderate irritants and will detect corrosive substances only through their inhibition of all cell activities.
(8) Since the origin of 3-dehydroretinol in epidermis is unknown, we have investigated the possible conversion of all-trans-retinol to 3-dehydroretinol by organ cultured keratome slices (0.3 mm) of human breast skin.
(9) A new semi-automatic, electrically-driven keratome with very exact micrometer -- adjustment allows for the first time a continuous cut without changing the direction of movement of the knife.
(10) When keratomed psoriatic epidermal slices were incubated in 5 X 10(-4) M papaverine or Ro 20-1724 the tissue levels of cAMP were increased 343% or 1395% respectively (p less than .001) with no concomitant change in the levels of cGMP.
(11) Considering the potential importance of growth factor stimulated phosphoinositide metabolism in the genesis of abnormal growth, we measured PI kinase activity in epidermal keratome biopsies from normal skin and the lesional and nonlesional skin of psoriatic patients.
(12) In functional assays using both the thymocyte proliferation assay and the LBRM.33 cell line, IL-1 activity from psoriatic involved skin keratomes was markedly reduced relative to that of uninvolved psoriatic keratomes and normal skin.
(13) Treated areas were removed by a keratome and a microsomal fraction was isolated from each biopsy.
(14) Immunoreactive IL-1 beta was found to be elevated in cytosolic extracts derived from involved psoriatic keratomes relative to keratomes of normal skin.
(15) Three microkeratome systems (Automatic Corneal Shaper (Steinway Instrument Company, Inc, San Diego, Calif), Draeger Lamellar Keratome (Storz Instrument GmbH, Heidelberg, Germany), and Microprecision test model (Microprecision Instrument Company, Inc, Phoenix, Ariz) were subjected to a concurrent and independent evaluation.
(16) C-myc, c-fos, and c-jun transcripts were significantly induced over in vivo levels 2-4 h after organ culture of normal or psoriatic keratome biopsies, demonstrating that these genes can be highly expressed in the context of tissue injury.
(17) Desmoplakins I and II (DP1 and DP2), major cytoskeletal structural proteins concentrated in desmosomes, have been purified in milligram quantities from keratomed pig tongue epithelium.
(18) Keratomed epidermal tissue from normal individuals and from the lesional and non-lesional skin of psoriasis patients served as source materials for the extraction, separation, and quantitation of eicosanoids that may be important to cutaneous function and pathophysiology.
(19) Using the rotating lamellar keratome, a simplified method for nonfreeze shaping of corneal tissue was developed.
(20) When keratome-sliced pig epidermis was floated on Hank's balanced salt solution, we observed a rapid decrease in the intracellular level of cyclic GMP.