(1) Hosts showed vaginal opening within 5 days and cornified vaginal smears by 9 days.
(2) These cationic molecules aggregate in vitro with keratin intermediate filaments, forming well ordered macrofibrils whose structure resembles the keratin pattern seen in the lower cornified layers.
(3) Female Albino Rats exposed to permanent light, have polycystic and anovulatory ovaries, with a vaginal cytology composed of cornified cells (persistent estrus) and a plasmatic hyperandrogenia.
(4) In addition, epidermal hyperproliferation, which floods the cornified cell compartment with incompletely formed units, results in hyperkeratosis.
(5) Despite such common profiles in the early signal transduction parameters, only 1 alpha,25(OH)2D3 induced formation of a cornified envelope characteristic of keratinocyte differentiation.
(6) The intermediate filaments are assembled from keratin monomers and the cornified envelope is assembled from a protein called involucrin and several other proteins.
(7) In this model, the smaller, less cornified lesions were more effectively treated with photodynamic therapy.
(8) To explore the possibility that TNF stimulates keratinocyte differentiation at least in part by regulating 1,25-(OH)2D production we examined the effect of TNF on both 1,25-(OH)2D production and differentiation (transglutaminase activity, cornified envelope formation) at different stages of differentiation.
(9) In feminized males given 20 microgram E2 neonatally, the vaginal epithelium exhibited well-differentiated stratified squamous organization, but was not cornified in seven out of the nine mice of this group.
(10) After repeated peptide treatments over 24 h, the number of cornified envelopes (a marker of terminal differentiation) was increased both in primary cultures and in the 308 cells.
(11) The disease is characterized by a cornifying verrucous proliferation of the squamous epithelium, without atypias or metastases.
(12) Its distribution is restricted to the granular layer of keratinized (cornified) stratified squamous epithelia.
(13) An increase in incorporation of both amino acids accompanied stratification and development of granular and cornified layers between 18 days of gestation and 3 to 5 days postpartum.
(14) The inclusion bodies were highly eosinophilic masses in the viable layer, and slightly basophilic, fine granules in the cornified layer.
(15) Switching of the cells from the low-calcium to the high-calcium medium resulted in the induction of terminal differentiation within 15 hours and was accompanied by increased cholesterol and protein synthesis, increased competence of cells to form cornified envelopes, and reduced association of 125I-LDL.
(16) The vaginal epithelium became multilayered with stratified or cornified surface layers and the uterus developed gross cystic glandular hyperplasia.
(17) Three cell lines of squamous-cell carcinoma and 3 of large-cell carcinoma origin were investigated for the expression of differentiation markers and functional parameters (proliferation, morphology, cornified envelope formation, involucrin staining, transglutaminase activity, adhesiveness and migration) under normal cell culture conditions and after treatment with the tumor promoter phorbol-12-myristate-13-acetate (PMA).
(18) In the margin of non cornified squamous cell carcinomas there are as well bud-like cytoplasmic protuberances like microvilli as microplicae.
(19) (1) Combination of techniques for extraction and purification of histidine rich protein established by several investigators were employed for comparison of histidine-rich protein in granular cells and cornified cells of newborn rats.
(20) The surface of the spine is covered by a scaly keratin of possibly sloughing cells, and the cornified layer on the spine is very thick (more than 100 mu), reaching 3 to 7 times the depth of the corresponding layer in other parts.
Horny
Definition:
(superl.) Having horns or hornlike projections.
(superl.) Composed or made of horn, or of a substance resembling horn; of the nature of horn.
(superl.) Hard; callous.
Example Sentences:
(1) Digestion of cytoplasmic components of horny cells was observed by electron microscopy, but both cell membranes and desmosomes remained intact.
(2) Strains of C. albicans differing in their abilities to secrete proteinase in vitro and to produce germ tube were inoculated onto the skin surface of newborn mice, and the invasion of the yeast cells into the horny layer was examined by histological techniques.
(3) Morphologic features of Malassezia(M.) furfur in the horny layer from clinical lesions of tinea versicolor were examined by scanning electron microscopy and compared with the appearance of fungus in the horny layer from normal skin and in culture.
(4) The absolute concentrations of 8-Methoxypsoralen were estimated in the horny layer, epidermis and dermis.
(5) In the next stage, the roof consisting of the malpighian layers is disrupted, and the vesicular fluid comes into contact with the horny layer.
(6) The systematic evaluation of the original curves takes into consideration amplitude, angle of climb and medium route and results in a horny layer sample-obtained successively from one and the same horny layer strip-series test area-impressioned by individual and regional horny layer conditions.
(7) The nature of the horny layer which, as the uppermost barrier takes over the main part of the protective function of the skin against all locally applied substances, is shortly outlined.
(8) Removal of the horny layer decreased epidermal IL 1-like activity.
(9) The superficial dermis contained horny cysts, similar to those present on the cheeks.
(10) Munro's microabscess under the horny layer also included IFN-gamma producing cells.
(11) The fluid was obtained from the skin surface of female mongrel dogs by transcutaneous suction after removal of the horny substance.
(12) The mockery continued when he noted semi-automatics had only two purposes: to kill people, and to let their owners go to a shooting range, "yell yeehaw, and get all horny at the rapid fire and the burning vapor spurting from the end of the barrel".
(13) In both sites the plasma membranes of the horny cells were thickened and there was a cytoplasmic meshwork of microfibrils in the cells.
(14) Epithelial cells changing from the granular stage of differentiation to the horny stage are more numerous, and reveal sequential events of transformation in finer detail in the rumen epithelium than in other keratinizing epithelia thus far studied in the electron microscope.
(15) Yet there is Samantha, bawdy as the Wife of Bath, always cheerfully horny and materialistic, utterly without Calvinic redeeming qualities, living at last with her devoted younger boy toy in LA in the Sex and the City movie – finally leaving him because she is just not cut out to mix her driving, unmediated sexual energy with commitment.
(16) "Before you hit puberty, you have this growing, really urgent sense of horniness."
(17) This reflected enhanced permeability resulting from reduction of the horny layer to less than one-half its normal thickness.
(18) Remaining reactivity with antibodies, but not lectins, was almost completely abolished immediately before the final disintegration of the desmosome structure in the lower horny layer.
(19) The calcified concretions are also seen in the lymphatic capillaries, the intraepidermal sweat ducts and horny layer; at a site they perforate the epidermis and penetrate in a sweat pore.
(20) Elastic fibres were prominent in the upper dermis, the lower levels of the epidermis and in the hyperkeratotic horny layer.