(a.) That which joins or links two things together; a bond or tie; a coupler.
(a.) Two of the same kind connected or considered together; a pair; a brace.
(a.) A male and female associated together; esp., a man and woman who are married or betrothed.
(a.) See Couple-close.
(a.) One of the pairs of plates of two metals which compose a voltaic battery; -- called a voltaic couple or galvanic couple.
(a.) Two rotations, movements, etc., which are equal in amount but opposite in direction, and acting along parallel lines or around parallel axes.
(v.) To link or tie, as one thing to another; to connect or fasten together; to join.
(v.) To join in wedlock; to marry.
(v. i.) To come together as male and female; to copulate.
Example Sentences:
(1) Spermine clearly activated 45Ca uptake by coupled mitochondria, but had no effect on Ca2+ egress from mitochondria previously loaded with 45Ca.
(2) After transfection in CH4C1 cells the two isoforms are coupled with adenylate cyclase while only the shortest isoform appears negatively coupled to phospholipase C. Functional D2 dopamine receptors are present in human prolactinomas.
(3) Ferrocene derivatives, in general, show a degree of versatility, coupling the electron-transfer reactions of many enzymes.
(4) Since intracellular Ca2+ seems to play a role in stimulus-secretion coupling and ion movements, several aspects of Ca2+ homeostasis have been investigated in CF.
(5) Couples in need of help will be "encouraged" to come to a private agreement.
(6) To get a better understanding of the different cell interactions during the immune response to a hapten-carrier complex, the effects of immunogenic or tolerogenic injections of various hapten-containing compounds on the responses induced by immunization with the same hapten coupled to protein carriers were studied.
(7) Such a science puts men in a couple of scientific laws and suppresses the moment of active doing (accepting or refusing) as a sufficient preassumption of reality.
(8) In contrast, strains carrying the substitutions Ile-30----Phe, Gly-33----Leu, Gly-58----Leu, and Lys-34----Val and the Lys-34----Val, Glu-37----Gln double substitution were found to possess a coupled phenotype similar to that of the wild type.
(9) Couples applying to in vitro fertilization were admitted into this project when the sperm concentration was greater than 20 million per mL and motility greater than 30 per cent.
(10) Large emission intensity fluctuations are observed from analyte species in inductively coupled plasmas.
(11) At the weekend the couple’s daughter, Holly Graham, 29, expressed frustration at the lack of information coming from the Foreign Office and the tour operator that her parents travelled with.
(12) These results coupled with previous studies support activation of benz[j]aceanthrylene via both 2 and cyclopenta ring epoxidation.
(13) Homologous insemination in 52 couples during a period of one year yields a conception rate of 38.5%.
(14) Following the hypothesis that infertile patients may present emotional conflicts with regard to the wish of having a child, psychodynamic interviews were carried out with 116 infertile couples concomitantly with their first consultation at the Sterility Department.
(15) The objective of this work was to determine the efficacy of an endoscopic approach coupled to a Nd:YAG laser fiber in performing arytenoidectomy.
(16) During the couple's 30-year marriage she had twice reported him to the police for grabbing her by the throat, before they divorced in 2005.
(17) The rate of indole production is increased about 4-fold when the aminoacrylate produced is converted to S-(hydroxyethyl)-L-cysteine by a coupled beta-replacement reaction with beta-mercaptoethanol.
(18) Single injections never produced more than one coupled pair in P20 or older rats.
(19) The extensive conversion of anti-BPDE to B[a]PT-10-sulfonate under conditions where sulfite enhances diolepoxide mutagenicity, when coupled with this enhancement of diolepoxide mutagenicity by B[a]PT-10-sulfonate in the reverse mutation assay, supports this novel B[a]P derivative as a mediator of the sulfite-dependent enhancement of B[a]P genotoxicity.
(20) Bobbing in warming waters, this ancient ice fossil will be gone in a couple of weeks.
Uncouple
Definition:
(v. t.) To loose, as dogs, from their couples; also, to set loose; to disconnect; to disjoin; as, to uncouple railroad cars.
(v. i.) To roam at liberty.
Example Sentences:
(1) Although each of palate and limb is concurrently susceptible to epigenetic regulation, their differential intrinsic genomic capabilities appear to have been uncoupled.
(2) Rhesus monkey BAT mitochondria (BATM) possess an uncoupling protein that is characteristic of BAT as evidenced by the binding of [3H]GDP, the inhibition by GDP of the high Cl- permeability or rapid alpha-glycerol-3-phosphate oxidation.
(3) Thus, 4'-OH-4-CB acts as both an uncoupler and an inhibitor of oxidative phosphorylation.
(4) We suggest that radiation-induced specific chromosome 2 rearrangement associated with IL-1 beta deregulation may initiate murine leukemogenesis through the uncoupling of normal proliferative control mechanisms in multipotential hemopoietic cells.
(5) The entry of CH3NH3+ supported by glucose oxidation in an F1F0-ATPase-deficient mutant was blocked by uncoupler.
(6) We report here, for the first time, the primary structure of uncoupling protein as established by amino acid sequencing.
(7) The present experiment was conducted to determine if a single direct dopamine (DA) agonist, apomorphine (APO), pretreatment could produce a rapid uncoupling of the striatal DA D-2 receptor from its G-proteins.
(8) A model is proposed in which this region interacts with a catalytic core to maintain the I state, and in which phosphorylation serves to uncouple this interaction.
(9) It was strongly inhibited by the metabolic inhibitor antimycin A and to a lesser extend by the uncoupler carbonylcyanide-m-chlorophenylhydrazone.
(10) It is concluded that the fatty acids "uncouple" the amino acid carrier proteins from the cytochrome-linked electron transport system (to which they may be coupled via protein interaction or via a cation gradient).
(11) It was concluded that LPS acted as an uncoupler of oxidative phosphorylation and that it produced effects similar to those observed with the classical uncoupler 2,4-dinitrophenol.
(12) These data indicate that the phenolic hydroxyl groups of xanthomegnin might contribute to its uncoupling action on the oxidative phosphorylation of mitochondria.
(13) The uncoupled enzyme, however, exhibited greater storage stability than the covalently linked enzyme at 25 degrees after 24 hrs and at 0 degrees after 21 days.
(14) In contrast, an uncoupler of mitochondrial respiration, sodium salicylate (375 mg per kg), increased the decarboxylation of alpha-ketoisocaproic acid (56.3% of the dose recovered as 14CO2 in 1 hr).
(15) Titration of glucose-depleted synaptosomes with pyruvate in the presence of either veratridine or uncoupler stimulates respiration in a Ca2+-independent manner.
(16) Stimulation of respiration, perhaps reflective of uncoupling of oxidative phosphorylation, was produced by an ochratoxin A concentration of 1 mM.
(17) Sodium nitrite, a substance with unknown promoting activity, effectively uncoupled cells.
(18) These effects of ATP are abolished by oligomycin and uncoupling agents and may, therefore, be reflections of the coupling of the mitochondrial ATP synthetase to the respiratory chain at the level of cytochrome c oxidase, which is the basis of the mechanism of coupling respiration to ATP synthesis and respiratory control.
(19) In the control group, the uncoupled respiration rate is also higher, while the ascorbate+ +TMPD oxidation rate is lower than in the cold- and cold + T-activin-treated groups.
(20) Marker incubation of ultrathin cryosections obtained by cryo transverse sectioning of IgG-labeled semithick cryosections shows also that penetration of uncoupled antibodies into cytoplasm and nuclei of chicken erythrocytes is limited.