(a.) Characterized by weakness or feebleness; decrepit; broken; falling to decay; shaky; unsafe.
(a.) Broken, weakened, or dissordered in intellect; shattered; demented; deranged.
(a.) Inordinately desirous; foolishly eager.
Example Sentences:
(1) The difference in Brazil will be the huge distances involved, with the crazy decision not to host the group stages in geographical clusters leading to logistical and planning nightmares.
(2) He argues that whenever you have periods of crazy expansion of virtual credit, like today, you either have to have a safety valve of forgiveness, like in Mesopotamia where you wiped the tablets clean every seven years, or you have an outbreak of social violence so intense you rip society apart.
(3) I saw my dad sitting in the audience, looking at me like, “Yes, he really is crazy.” Having listened to thousands of people, I realised we had a narrow view of what the environment is.
(4) Updated at 8.17pm GMT 8.14pm GMT Yet another crazy statistic Seems like we’ve had a few of these today.
(5) Then their daughter comes in, or their wife, or their girlfriend, and they've just been to Pilates, and the next day they start looking up Pilates porn, or something crazy like that, and they feel even worse.
(6) The Hull City manager, Steve Bruce , has admitted his side need to pull off a couple of “crazy results” if they are to preserve their Premier League status in a frantic end-of-season run-in.
(7) Families picnic between games of crazy golf or volleyball, bathers brave the shallows, children splash in the saltwater lido.
(8) As soon as I called them and was like, 'Hey guys, it's OK, I'm not smoking meth or anything,' it was OK." He adds, frowning: "I don't really know why it happened… My girlfriend told me everyone had been saying, [he puts on a sulky voice] 'Man, Mac's shows aren't crazy any more.'
(9) "I remember ... crying and thinking, 'I'm just gonna go crazy on him one day.'"
(10) This may sound crazy, but with each passing day, Major League Soccer, which shares part of sporting calendar with the baseball season, becomes more and more of a long term threat to MLB, never mind what happens when the NFL kicks off in September.
(11) If you can't get your child into there … It's crazy.
(12) Her mother said she had made her “so proud” and her “gorgeous crazy” partner had made her world “a happy place”.
(13) "I knew that police officers had been hurt and things were on fire and it had all got crazy," the constable said.
(14) You see Nadal play a tennis match,” Godín explains, “and it drives you crazy because he always does the same thing and the guy is No1.
(15) In his book Fight the Power , Chuck rails against everything from Hollywood to the sports industry for portraying blacks as 'watermelon stealin', chicken eatin', knee knockin', eye poppin' lazy, crazy, dancin', submissive, Toms.
(16) After a stroke (left hemisphere), which mainly produced serious aphasia, I (the patient) felt crazy two or three times when someone said something I expected him to say.
(17) But at the same time we were supporting the industry and talking it up, which it deserves, some of our competitors were talking it down in their own products … that’s just crazy and a lack of leadership that frankly is irresponsible and it’s got to stop.” In a rare public appearance to mark the Australian newspaper’s 50th anniversary, Mitchell said the broadsheet newspaper was worth $50m in “cover price revenue” alone and it was too soon to walk away from print.
(18) "Like" is a preposition, said the accusers, and may take only a noun phrase object, as in "crazy like a fox" or "like a bat out of hell".
(19) And rare to see scripted too – normally women are only allowed to look dangerous if they’re playing a crazy person.
(20) She could actually be crazy,” and implying that she had been unfaithful for her husband.
Loco
Definition:
(adv.) A direction in written or printed music to return to the proper pitch after having played an octave higher.
(n.) A plant (Astragalus Hornii) growing in the Southwestern United States, which is said to poison horses and cattle, first making them insane. The name is also given vaguely to several other species of the same genus. Called also loco weed.
Example Sentences:
(1) Staplers were used and therefore the choice between resection or amputation was determined by the degree of loco-regional infiltration of the neoplasm.
(2) No patient developed metastases without previous clinically-evident invasive loco-regional disease.
(3) It is of mechanical or mixed type, accompanied by local, pseudo-inflammatory signs being either apparent or discrete, very elective and very sharp pain upon palpation of a very limited area of a condyle or a tibial plate, with hyperfixation located through scintigraphy with technetium 99m polyphosphates, and regressing either spontaneously, or more quickly under treatment, of which thyrocalcitone is the essential part, without undergoing a phase of intense loco-regional demineralization.
(4) There was complete loco-regional tumour control in 51% of all patients (with and without distant metastases).
(5) Two of the 37 patients who underwent mastectomy developed loco-regional recurrences; both had invasive foci at their first operation and remain disease free at 8 years.
(6) Among the 25 cases of recurrence, 1 was exclusively local and 6 were loco-regional (T and N), while 18 patients presented metastatic progression, either exclusively, or with local or lymph node failure.
(7) All patients where managed similarly: 3 to 4 courses of chemotherapy (CMF: n = 24; AVCF: n = 42), then loco regional irradiation therapy with cobalt 60, followed by maintenance chemotherapy, only if the first chemotherapy had proved effective (CMF: n = 13; AVCF: n = 27).
(8) Since there seems to be a direct relation between tumor size and the chance of loco-regional recurrence and since salvage operations for local failure are not uniformly successful, electrofulguration for cure must be reserved for the very rare patient with a very small early-stage rectal cancer.
(9) Although the recurrence rates of 37% and 49% by 50 Gy and 40 Gy were not statistically different, there was a strong trend of a better control rate of loco-regional carcinoma by higher radiation doses.
(10) From these results, it is reasonable to conclude that Kupffer cells alone are activated in a condition without a supply of monocytes from peripheral blood; proliferate and cluster in the hepatic sinusoids; transform into peroxidase-negative macrophages, epithelioid cells, and multinuclear giant cells; and participate in granuloma formation in loco together with T lymphocytes.
(11) Patients with T1 squamous cell carcinomas had, in fact, the best prognosis (26.5% recurred) among the subgroups obtained by stratification of T number and cell type together; loco-regional failure as exclusive modality of relapse had a 5-year rate of 19.7% and metastatic failure of 30.0%.
(12) In patients with Dukes' B tumours, an increased risk of loco-regional recurrence was associated with perineural invasion, tumour located less than 10 cm from the anal verge, patient aged above 70 years, and small tumour size.
(13) An effort was made to neutralize the virus in loco either by infiltration of the inoculation site with povidone-iodine or with monoclonal antibodies, or by cauterization and excision.
(14) To establish whether predictive clinical patterns of disease occur in localized Non-Hodgkin's lymphoma, survival and relapse patterns for 496 patients with stage I and II non-Hodgkin's lymphoma (NHL) treated with loco-regional irradiation (XRT) alone were examined.
(15) Radiotherapy alone may be appropriate treatment for extensive loco-regional tumours or in those that have already metastasized.
(16) Thus, adjuvant systemic treatment alone (chemotherapy or tamoxifen) did not prevent loco-regional recurrences in high-risk patients after mastectomy and axillary lymph node sampling.
(17) Three factors were found to be statistically significant: adjuvant hormonotherapy, loco-regional metastases, adjuvant adriamycin containing regimen (pejorative prognostic factor).
(18) Risk factors for loco-regional relapse (seven cases) included: large tumour bulk, treatment by XRT alone and use of 'limited' radiation fields.
(19) Following initial promising results in terms of loco-regional disease control in this group of high-risk patients, the protocol was extended to include 34 patients defined as having locally extensive disease.
(20) These changes may be related to the endothelial damage present scleroderma patients I the consequent "in loco" activation of blood coagulation may cause the microthrombosis that is very often observed in the earliest phases of the disease.