(v. t.) To bring into being; to form out of nothing; to cause to exist.
(v. t.) To effect by the agency, and under the laws, of causation; to be the occasion of; to cause; to produce; to form or fashion; to renew.
(v. t.) To invest with a new form, office, or character; to constitute; to appoint; to make; as, to create one a peer.
Example Sentences:
(1) Apparently, the irradiation with visible light of a low intensity creates an additional proton gradient and thus stimulates a new replication and division cycle in the population of cells whose membranes do not have delta pH necessary for the initiation of these processes.
(2) Then the esophagogastric variceal network was thrombosed by means of a catheter introduced during laparotomy, which created a portoazygos disconnection.
(3) Along the spectrum of loyalties lie multiple loyalties and ambiguous loyalties, and the latter, if unresolved, create moral ambiguities.
(4) The new Somali government has enthusiastically embraced the new deal and created a taskforce, bringing together the government, lead donors (the US, UK, EU, Norway and Denmark), the World Bank and civil society.
(5) When reformist industrialist Robert Owen set about creating a new community among the workers in his New Lanark cotton-spinning mills at the turn of the nineteenth century, it was called socialism, not corporate social responsibility.
(6) Antigen of HK-9 strain created in this area a characteristic pattern with all sera containing the specific anti-E. histolytica antibodies and, therefore, EITB can be used for excluding false positive results in ELISA.
(7) Based on the results of the Community AIM Exploratory Action, further collaborative work is required at EEC level to create an Integrated Health Information Environment (IHE) allowing essentially for integration, modularity and security.
(8) The diagnosis of an arterial injury may be readily apparent, but the excellent upper-extremity collateral circulation may create palpable distal pulses despite a significant proximal arterial injury.
(9) In this analysis, combining data sources creates estimates for the proportion exposed that are different from estimates in either of the original information sources.
(10) An experience in working out and introduction of a system of failure-free performance work as one of the most important steps in creating a complex system for the production quality control at the Leningrad combine "Krasnogvardeets" is described.
(11) This hydrostatic pressure may well be the driving force for creating channels for acid and pepsin to cross the mucus layer covering the mucosal surface.
(12) Networking has become a powerful means of creating change.
(13) Experimental photogenic epilepsy attained by creating GPIE in the EGB with the aid of TT, is proposed as a model for studying the mechanism of epileptogenesis and testing the efficacy of anticonvulsive drugs.
(14) The system has been successfully used for 18 months to create directories for a teaching file, for presentations, and for clinical research.
(15) Van Rompuy and Ashton got their jobs at the same time as a result of the Lisbon treaty, which created the posts of president of the European council and high representative for foreign and security policy.
(16) Even so, the controversy over the last assessment, and the political polarisation in America and other countries around climate science and the need for climate action, have created an additional layer of scrutiny around next week's report.
(17) Since he was created, he has appeared at several robotic fairs across China, but spends most of his time in deep meditation on an office shelf in Longquan.
(18) The government has been counting on the fact that their attacks on the NHS are too complicated to be widely understood: after all, their Health and Social Care Act was much longer than the legislation that created the NHS under Aneurin Bevan’s watch in the first place.
(19) Various forms of inactive data storage and archiving in machine-readable form are available to address this dilemma, yet these solutions can create even more difficult problems.
(20) The toxins all create pores in the cell membrane of target cells leading to eventual cell lysis and they appear to require Ca2+ for cytotoxic activity.
Rough
Definition:
(n.) Having inequalities, small ridges, or points, on the surface; not smooth or plain; as, a rough board; a rough stone; rough cloth.
(n.) Not level; having a broken surface; uneven; -- said of a piece of land, or of a road.
(n.) Not polished; uncut; -- said of a gem; as, a rough diamond.
(n.) Tossed in waves; boisterous; high; -- said of a sea or other piece of water.
(n.) Marked by coarseness; shaggy; ragged; disordered; -- said of dress, appearance, or the like; as, a rough coat.
(n.) Hence, figuratively, lacking refinement, gentleness, or polish.
(n.) Not courteous or kind; harsh; rude; uncivil; as, a rough temper.
(n.) Marked by severity or violence; harsh; hard; as, rough measures or actions.
(n.) Loud and hoarse; offensive to the ear; harsh; grating; -- said of sound, voice, and the like; as, a rough tone; rough numbers.
(n.) Austere; harsh to the taste; as, rough wine.
(n.) Tempestuous; boisterous; stormy; as, rough weather; a rough day.
(n.) Hastily or carelessly done; wanting finish; incomplete; as, a rough estimate; a rough draught.
(n.) Produced offhand.
(n.) Boisterous weather.
(n.) A rude fellow; a coarse bully; a rowdy.
(adv.) In a rough manner; rudely; roughly.
(v. t.) To render rough; to roughen.
(v. t.) To break in, as a horse, especially for military purposes.
(v. t.) To cut or make in a hasty, rough manner; -- with out; as, to rough out a carving, a sketch.
Example Sentences:
(1) By 24 hr, rough endoplasmic reticulum in thecal cells increased from 4.2 to 7% of cell volume, while the amount in granulosa cells increased from less than 3.5% to more than 10%; the quantity remained relatively constant in the theca but declined to prestimulation values in the granulosa layer.
(2) Thus, it appears that neuronal loss may account for up to roughly half of the striatal D2 receptor loss during aging.
(3) The cis isomer was retained longer in liver, particularly in mitochondria, but had low retention in that portion of the endoplasmic reticulum isolated as the rough membrane fraction.
(4) The results indicated that roughly 25% of patients treated in this way will become hypothyroid after 5 years and that 85% are cured (need no further therapy during the follow-up period) using a single dose of iodine-131.
(5) This heretogeneity occurred mainly as a progressive, decreasing gradient in the first half of this pathway, between the rough endoplasmic reticulum and the mi-cisternae of the Golgi apparatus.
(6) Electron microscopy revealed a well-developed rough endoplasmic reticulum, an enlarged Golgi apparatus and many highly electron-dense secretory granules resembling those of Clara cells.
(7) Four fractions enriched, respectively, in plasma membrane (PM), smooth endoplasmic reticulum (SER), rough endoplasmic reticulum (RER), and mitochondria were isolated from estrogen-dominated rat myometrium.
(8) For trials in which the target was present in the array, RT functions were roughly symmetric, the shortest RTs being for extreme distractor ratios, and the longest RTs being for arrays in which there were an equal number of each distractor type.
(9) Classic technics of digital image analysis and new algorithms were used to improve the contrast on the full image or a portion of it, contrast a skin lesion with statistical information deduced from another lesion, evaluate the shape of the lesion, the roughness of the surface, and the transition region from the lesion to the normal skin, and analyze a lesion from the chromatic point of view.
(10) Electron microscopic evaluation of microsomal fractions showed elements of the plasma membrane, including cilia and microvilli, as well as rough and smooth endoplasmic reticulum.
(11) The local guide led us down a rough, uneven pathway, talking as he went.
(12) It's the roughly $2bn in revenue grossed by his blockbuster movies, some of which he had to be talked into making.
(13) The interaction between PE and E-IgG involved the extension of micropseudopods toward adherent E-IgG, the formation of a linear uniform cap of roughly 200 A between opposing cell membranes, the ingestion of E-IgG by PE into a membrane-lined compartment, and the disintegration of the ingested ligand into membranous debris.
(14) Ultracentrifugally separated HDL2 and HDL3 roughly corresponded to HDL2e and HDL3e, respectively.
(15) The locations of these 15 insertion sites correlate well with the roughly estimated locations of five of the DNase I-hypersensitive subregions.
(16) The Lords will vote on three key amendments: • To exclude child benefit from the cap calculation (this would roughly halve the number of households affected).
(17) The unique structure we describe is a cytoplasmic organelle which, like annulate lamellae, is closely associated with the endoplasmic reticulum and is presumed to be related to the genesis of rough-surfaced endoplasmic reticulum in tumor cells.
(18) Besides the rough, wrinkled, and brown or black surface of the fingertips, microwrinkles of the epidermis occur on the skin ridges, which have so far not been described.
(19) Ultrastructural examination of noncartilaginous regions of the tumor demonstrated mesenchymal cells with features suggestive of cartilaginous differentiation, viz, scalloped cell membranes, sac-like distension of abundant rough endoplasmic reticulum, and a matrix containing fibrillary and finely granular material.
(20) That, roughly, was the theme of the Wednesday Play, Cathy Come Home, (BBC1) directed by Kenneth Loach, produced by Tony Garnett.