(n.) Qualified to criticise, or pass judgment upon, literary or artistic productions.
(n.) Pertaining to criticism or the critic's art; of the nature of a criticism; accurate; as, critical knowledge; a critical dissertation.
(n.) Inclined to make nice distinctions, or to exercise careful judgment and selection; exact; nicely judicious.
(n.) Inclined to criticise or find fault; fastidious; captious; censorious; exacting.
(n.) Characterized by thoroughness and a reference to principles, as becomes a critic; as, a critical analysis of a subject.
(n.) Pertaining to, or indicating, a crisis, turning point, or specially important juncture; important as regards consequences; hence, of doubtful issue; attended with risk; dangerous; as, the critical stage of a fever; a critical situation.
Example Sentences:
(1) The newborn with critical AS typically presents with severe cardiac failure and the infant with moderate failure, whereas children may be asymptomatic.
(2) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(3) The interaction of the antibody with both the bacterial and the tissue derived polysialic acids suggests that the conformational epitope critical for the interaction is formed by both classes of compounds.
(4) Ursodeoxycholate was the only dihydroxy bile salt which was able to solubilize phospholipid (although not cholesterol) below the critical micellar concentration.
(5) The pathology resulting from a missense mutation at residue 403 further suggests that a critical function of myosin is disrupted by this mutation.
(6) The criticism over the downgrading of the leader of the Lords was led by Lord Forsyth of Drumlean, a former Scotland secretary, who is a respected figure on the right.
(7) Anaerobes, in particular Bacteroides spp., are the predominant bacteria present in mixed intra-abdominal infections, yet their critical importance in the pathogenicity of these infections is not clearly defined.
(8) Even former Florida governor Jeb Bush, one of Trump’s chief critics, said ultimately, “anybody is better than Hillary Clinton”.
(9) Also critical to Mr Smith's victory was the decision over lunch of the MSF technical union's delegation to abstain on the rule changes.
(10) Critics say he is unelectable as prime minister and will never be able to implement his plans, but he has nonetheless pulled attention back to an issue that many thought had gone away for good.
(11) The high incidence of infant astigmatism has implications for critical periods in human visual development and for infant acuity.
(12) It isn't share ownership but the way people are managed that's critical.
(13) GlaxoSmithKline was unusually critical of the decision by Nice, the National Institute for Health and Clinical Excellence, and also the Scottish Medicines Consortium, to reject its drug belimumab (brand name Benlysta) in final draft guidance.
(14) The present studies indicated that the critical level at which HbCO influenced VO2 max was approximately 4.3%.
(15) Brewdog backs down over Lone Wolf pub trademark dispute Read more The fast-growing Scottish brewer, which has burnished its underdog credentials with vocal criticism of how major brewers operate , recently launched a vodka brand called Lone Wolf.
(16) Last week the WHO said the outbreak had reached a critical point, and announced a $200m (£120m) emergency fund.
(17) Critical in this understanding are the subtle changes that occur in the individual patient, reflecting the natural history of the disease or response to its treatment.
(18) That’s a criticism echoed by Democrats in the Senate, who issued a report earlier this month criticising Republicans for passing sweeping legislation in July to combat addiction , the Comprehensive Addiction and Recovery Act (Cara), but refusing to fund it.
(19) He's called out for his lack of imagination in a stinging review by a leading food critic (Oliver Platt) and - after being introduced to Twitter by his tech-savvy son (Emjay Anthony) - accidentally starts a flame war that will lead to him losing his job.
(20) Critics of wind power peddle the same old myths about investment in new energy sources adding to families' fuel bills , preferring to pick a fight with people concerned about the environment, than stand up to vested interests in the energy industry, for the hard-pressed families and pensioners being ripped off by the energy giants.
Major
Definition:
(a.) Greater in number, quantity, or extent; as, the major part of the assembly; the major part of the revenue; the major part of the territory.
(a.) Of greater dignity; more important.
(a.) Of full legal age.
(a.) Greater by a semitone, either in interval or in difference of pitch from another tone.
(a.) An officer next in rank above a captain and next below a lieutenant colonel; the lowest field officer.
(a.) A person of full age.
(a.) That premise which contains the major term. It its the first proposition of a regular syllogism; as: No unholy person is qualified for happiness in heaven [the major]. Every man in his natural state is unholy [minor]. Therefore, no man in his natural state is qualified for happiness in heaven [conclusion or inference].
(a.) A mayor.
Example Sentences:
(1) In contrast, resting cells of strain CHA750 produced five times less IAA in a buffer (pH 6.0) containing 1 mM-L-tryptophan than did resting cells of the wild-type, illustrating the major contribution of TSO to IAA synthesis under these conditions.
(2) With NaCl as the major constituent of the bathing solution (potassium-free pipette and external solutions) the reversal potential (Er) of the noradrenaline-evoked current was about 0 mV.
(3) After 4 to 6 hours of recirculation, accumulation of vasoactive amine, 5-hydroxytryptamine, its major metabolite, 5-hydroxyindole acetic acid, and its precursor amino acid, tryptophan were detected.
(4) The major treatable risk factors in thromboembolic stroke are hypertension and transient ischemic attacks (TIA).
(5) The promoters of the adenovirus 2 major late gene, the mouse beta-globin gene, the mouse immunoglobulin VH gene and the LTR of the human T-lymphotropic retrovirus type I were tested for their transcription activities in cell-free extracts of four cell lines; HeLa, CESS (Epstein-Barr virus-transformed human B cell line), MT-1 (HTLV-I-infected human T cell line without viral protein synthesis), and MT-2 (HTLV-I-infected human T cell line producing viral proteins).
(6) The data suggest that major differences may exist between ruminants and non-ruminants in the response of liver metabolism both to lactation per se and to the effects of growth hormone and insulin.
(7) Then a handful of organisers took a major bet on the power of people – calling for the largest climate change mobilisation in history to kick-start political momentum.
(8) This finding is of major importance for persons treated with diltiazem who engage in sport.
(9) Blatter requires a two-thirds majority of the 209 voters to triumph in the opening round, with a simple majority required if it goes to a second round.
(10) Further analysis with two other synthetic peptides (212Cys to 222Glu and Cys X 221Ile to 236Glu) indicated that the dodecapeptide Ile-Glu-Phe-Gln-Lys-Asn-Asn-Arg-Leu-Leu-Glu mimicked either the whole or a major part of the neutralization epitope.
(11) Inadequate treatment, caused by a lack of drugs and poorly trained medical attendants, is also a major problem.
(12) Even so, amputation of fifteen extremities and four other major excisions were required in twelve patients.
(13) In this study, standby and prophylactic patients had comparable success and major complication rates, but procedural morbidity was more frequent in prophylactic patients.
(14) These major departmental transformations are being run in isolation from each other.
(15) Epidemiological studies on low risks involve a number of major methodological difficulties.
(16) Given Australia’s number one position as the worst carbon emitter per capita among major western nations it seems hardly surprising that islanders from Fiji, Samoa, Vanuatu and other small island developing states have been turning to Australia with growing exasperation demanding the country demonstrate an appropriate response and responsibility.
(17) The time-course and dose-response for this modification of pp60c-src paralleled PDGF-induced increases in phosphorylation of pp36, a major cellular substrate for several tyrosine-specific protein kinases.
(18) The degree of increase in Meth responsiveness elicited by the initial provocation is a major factor in determining the airway response to a subsequent HS challenge.
(19) On the other hand, the majority of gynecologic patients with pelvic infections are young and healthy.
(20) Confidence is the major prerequisite for a doctor to be able to help his seriously ill patient.