(adv.) In a critical manner; with nice discernment; accurately; exactly.
(adv.) At a crisis; at a critical time; in a situation, place, or condition of decisive consequence; as, a fortification critically situated.
Example Sentences:
(1) The newborn with critical AS typically presents with severe cardiac failure and the infant with moderate failure, whereas children may be asymptomatic.
(2) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(3) The interaction of the antibody with both the bacterial and the tissue derived polysialic acids suggests that the conformational epitope critical for the interaction is formed by both classes of compounds.
(4) Ursodeoxycholate was the only dihydroxy bile salt which was able to solubilize phospholipid (although not cholesterol) below the critical micellar concentration.
(5) The pathology resulting from a missense mutation at residue 403 further suggests that a critical function of myosin is disrupted by this mutation.
(6) The criticism over the downgrading of the leader of the Lords was led by Lord Forsyth of Drumlean, a former Scotland secretary, who is a respected figure on the right.
(7) Anaerobes, in particular Bacteroides spp., are the predominant bacteria present in mixed intra-abdominal infections, yet their critical importance in the pathogenicity of these infections is not clearly defined.
(8) Even former Florida governor Jeb Bush, one of Trump’s chief critics, said ultimately, “anybody is better than Hillary Clinton”.
(9) Also critical to Mr Smith's victory was the decision over lunch of the MSF technical union's delegation to abstain on the rule changes.
(10) Critics say he is unelectable as prime minister and will never be able to implement his plans, but he has nonetheless pulled attention back to an issue that many thought had gone away for good.
(11) The high incidence of infant astigmatism has implications for critical periods in human visual development and for infant acuity.
(12) It isn't share ownership but the way people are managed that's critical.
(13) GlaxoSmithKline was unusually critical of the decision by Nice, the National Institute for Health and Clinical Excellence, and also the Scottish Medicines Consortium, to reject its drug belimumab (brand name Benlysta) in final draft guidance.
(14) The present studies indicated that the critical level at which HbCO influenced VO2 max was approximately 4.3%.
(15) Brewdog backs down over Lone Wolf pub trademark dispute Read more The fast-growing Scottish brewer, which has burnished its underdog credentials with vocal criticism of how major brewers operate , recently launched a vodka brand called Lone Wolf.
(16) Last week the WHO said the outbreak had reached a critical point, and announced a $200m (£120m) emergency fund.
(17) Critical in this understanding are the subtle changes that occur in the individual patient, reflecting the natural history of the disease or response to its treatment.
(18) That’s a criticism echoed by Democrats in the Senate, who issued a report earlier this month criticising Republicans for passing sweeping legislation in July to combat addiction , the Comprehensive Addiction and Recovery Act (Cara), but refusing to fund it.
(19) He's called out for his lack of imagination in a stinging review by a leading food critic (Oliver Platt) and - after being introduced to Twitter by his tech-savvy son (Emjay Anthony) - accidentally starts a flame war that will lead to him losing his job.
(20) Critics of wind power peddle the same old myths about investment in new energy sources adding to families' fuel bills , preferring to pick a fight with people concerned about the environment, than stand up to vested interests in the energy industry, for the hard-pressed families and pensioners being ripped off by the energy giants.
Discernment
Definition:
(n.) The act of discerning.
(n.) The power or faculty of the mind by which it distinguishes one thing from another; power of viewing differences in objects, and their relations and tendencies; penetrative and discriminate mental vision; acuteness; sagacity; insight; as, the errors of youth often proceed from the want of discernment.
Example Sentences:
(1) However, no evidence could be discerned to support its validity as a measure of a patient's treatment outcome.
(2) Of 55 new open reading frames analysed by gene disruption, three are essential genes; of 42 non-essential genes that were tested, 14 show some discernible effect on phenotype and the remaining 28 have no overt function.
(3) This was apparent by standard flux techniques only in low (65 mM) Na solutions, but was readily discernible in normal Na (125 mM) with the "lanthanum-residual" technique.
(4) By this method two types of granules have been discerned according to their different contrasts.
(5) Several stages in its histogenesis may be discerned: I. focal necroses of hepatic cells associated with their invasion with lister Listeria; 2. appearance of cellular elements around the foci of necroses with subsequent formation of granulemas consisting mainly of leucocytes and lymphoid cells; 3. development of necrobiotic changes in the central areas of granulemas with concomitance of exudative processes; 4. organization of necrotic foci with subsequent scarring.
(6) Significant increment in lipid peroxidation was discernible in brain, liver and muscle.
(7) While there's no discernible forró influence in the dreamy 80s indie-guitar music of Fortaleza's Cidadão Instigado, they do take influence from popular local style brega, a 1970s and 80s Brazilian romantic pop music.
(8) Furthermore, individual AgNOR dots were much more readily discerned in cell imprints than in sections, and this appears to be the method of choice if pathologists wish to at least approach absolute rather than relative AgNOR counts.
(9) In order to assess the sensitivity of these techniques, and to discern minimal criteria for their conduct, a survey of 113 human lymphocyte cytogenetic surveillance studies conducted between 1965 and 1984 has been undertaken.
(10) Changes in the secretory process were discernible as of day 1 in all three tumors, with a dramatic reduction of exocytosis and intracellular accumulation of PRL-immunoreactive granules.
(11) The advent of cyclosporine A provides the dermatologist with a new therapeutic strategem in the management of psoriasis, although the long-term safety of such interventional therapy remains to be discerned.
(12) Histologically, no discernible changes in the hair cells or sensory hairs were found with a scanning electron microscope at about 6 hours after 10 krad irradiation, while with a transmission electron microscope, the outer hair cells in the basal coil of the cochlea were found to be mostly destroyed.
(13) However, by phase microscopy, no changes are discernible within the first 12-18 h. Since the primary NGF receptor appears to be a membrane receptor, it seemed likely that some of the initial responses to the factor may be surface related.
(14) Whereas no discernible differences on survival were documented on a long-term basis, when patient who ultimately recurred in each group were compared, a substantial and statistically significant prolongation of the free-of-disease interval from surgery to recurrence and of survival from recurrence to death are revealed.
(15) The results suggest that TGF-beta 1 has powerful anti-inflammatory effects, mimicking in some respects the beneficial effects of immunosuppressive drugs in these experimental models of autoimmune disease, but without discernable adverse effects.
(16) Temporal differences in the expression of sugar-binding proteins and different patterns of staining of the component cell types of human placenta were discerned, especially pronounced for alpha-fucoside-specific binding in the trophoblast and alpha-glucoside-specific binding in fetal and maternal macrophages.
(17) They’re all basically the same, but the tiny, barely discernible differences between them consume vast amounts of energy and generate heartache for everyone involved.
(18) Judged radiographically, partial obliteration (pulp chamber not discernible, root canal markedly narrowed but clearly visible) had occurred in 44 teeth (36%).
(19) Starch ingestion had no discernible effect on postprandial lipemia.
(20) We conclude that long-term prophylaxis with TMP-SMZ does not produce discernable hematologic, renal, or hepatic toxicity in renal transplant recipients nor does it augment nephrotoxicity with cyclosporine or increase the risk of rejection.