(a.) Having the form of a cross; appertaining to a cross; cruciform; intersecting; as, crucial ligaments; a crucial incision.
(a.) Severe; trying or searching, as if bringing to the cross; decisive; as, a crucial test.
Example Sentences:
(1) Therefore, the measurement of the alpha-antitrypsin content plays the crucial part in differential diagnosis of primary (hereditary determined) and secondary (obstructive) emphysema.
(2) At first it looked as though the winger might have shown too much of the ball to the defence, yet he managed to gain a crucial last touch to nudge it past Phil Jones and into the path of Jerome, who slipped Chris Smalling’s attempt at a covering tackle and held off Michael Carrick’s challenge to place a shot past an exposed De Gea.
(3) The agriculture ministry raised the risk level of the virus spreading from moderate to high on Tuesday across the country, at a crucial time for the industry.
(4) Conservative commentators responded with fury to what they believed was inappropriate meddling at a crucial moment in the town hall debate.
(5) Although the performance aspects of electronic displays are crucial considerations in workstation design, experience suggests that human factors in mechanical operation, software accessibility, and workstation environment are also important.
(6) The secretary of state should work constructively with frontline staff and managers rather than adversarially and commit to no administrative reorganisation.” Dr Jennifer Dixon, chief executive, Health Foundation “It will be crucial that the next government maintains a stable and certain environment in the NHS that enables clinical commissioning groups (CCGs) to continue to transform care and improve health outcomes for their local populations.
(7) The results suggest that the ACTH-containing part of the hypothalamus around the PVH is crucially involved in the organization of grooming behaviour.
(8) A functional impairment of the amino acid transport systems at the level of the blood-brain barrier seems to play a crucial role in causing deleterious modifications of the synaptic neurotransmission in the central nervous system.
(9) The cerebral distribution and regulation of excitatory amino acid levels may play a crucial role in neuronal development.
(10) Imagining faces was also the only condition that led to an increase of activity in the left inferior occipital region which has been suggested by previous studies as being a crucial area for visual imagery.
(11) This is the most crucial issue of our time and the people must be heard, not criminalised."
(12) Therefore it is crucial to investigate the role of glucocorticoids in non-pituitary tumours and this requires an understanding of the molecular mechanisms involved in glucocorticoid inhibition of the normal POMC gene in the pituitary.
(13) The agreement, hailed as a "landmark" deal and a breakthrough by politicians and the green lobby alike, came before a crucial EU summit opening in Brussels tomorrow at which 27 prime ministers and presidents are supposed to finalise an ambitious package to cut greenhouse gas emissions by 20% by 2020.
(14) A comparison of the pharmacokinetics as well as the teratogenicity between cyclophosphamide and some specific deuterium-labeled analogues showed that the isotope effect observed can be related to a particular metabolic pathway crucial for teratogenic activation by this drug.
(15) The crucial issue of whether subtle behavioral, intellectual, and developmental impairment occurs in young children, as a result of lead-induced CNS damage is discussed in detail.
(16) The crucial point in all likelihood is the nature of this heme-binding protein.
(17) Standard criteria for staging and response evaluation, including pathologic documentation of remission status, are crucial.
(18) Given that a post-poll economy still registers as a crucial issue among undecided voters, and that matters economic are now his BBC day job, that was hardly surprising.
(19) Overall, these results confirm that the medial septum plays a crucial role in the acquisition of problem solving.
(20) He is joined by Cathy O’Toole, the ALP candidate for the crucial swing seat of Herbert where Rudd’s campaign bus has stopped on Sunday evening.
Main
Definition:
(n.) A hand or match at dice.
(n.) A stake played for at dice.
(n.) The largest throw in a match at dice; a throw at dice within given limits, as in the game of hazard.
(n.) A match at cockfighting.
(n.) A main-hamper.
(v.) Strength; force; might; violent effort.
(v.) The chief or principal part; the main or most important thing.
(v.) The great sea, as distinguished from an arm, bay, etc. ; the high sea; the ocean.
(v.) The continent, as distinguished from an island; the mainland.
(v.) principal duct or pipe, as distinguished from lesser ones; esp. (Engin.), a principal pipe leading to or from a reservoir; as, a fire main.
(a.) Very or extremely strong.
(a.) Vast; huge.
(a.) Unqualified; absolute; entire; sheer.
(a.) Principal; chief; first in size, rank, importance, etc.
(a.) Important; necessary.
(a.) Very; extremely; as, main heavy.
Example Sentences:
(1) In conclusion, the efficacy of free tissue transfer in the treatment of osteomyelitis is geared mainly at enabling the surgeon to perform a wide radical debridement of infected and nonviable soft tissue and bone.
(2) Aggregation was more frequent in low-osmolal media: mainly rouleaux were formed in ioxaglate but irregular aggregates in non-ionic media.
(3) The main clinical features pertaining to the concept of the "psycho-organic syndrome" (POS) were investigated in a sample of children who suffered from severe craniocerebral trauma.
(4) Squadron Leader Kevin Harris, commander of the Merlins at Camp Bastion, the main British base in Helmand, praised the crews, adding: "The Merlins will undergo an extensive programme of maintenance and cleaning before being packed up, ensuring they return to the UK in good order."
(5) The main finding of this study is that diabetic adolescents with a high erythrocyte Na,Li countertransport rate have an arterial pressure significantly higher than patients with normal Na,Li countertransport fluxes.
(6) We also show that the gene of the main capsid protein is expressed from its own promoter in an Escherichia coli strain.
(7) In schizophrenic patients the density of dopamine uptake sites in the basal ganglia was slightly reduced, mainly in the middle third of putamen.
(8) One of the main users is coastal planning organizations and conservation organizations that are working on coral reefs.
(9) Immunofluorescence analysis of Pr-28 antigen showed that the antigen was localized mainly in perinuclear cytoplasm.
(10) The main result of the correspondence analysis is a geometric map of this relationship showing how the relative frequencies of headache types change with age.
(11) Myocardial ischaemia was induced in perfused rabbit hearts by ligating the left main coronary artery.
(12) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
(13) Statistically significant differences were found mainly in the randomized trial, where during the first and second years, respectively, adenoidectomy subjects had 47% and 37% less time with otitis media than control subjects and 28% and 35% fewer suppurative (acute) episodes than control subjects.
(14) One of the main components was confirmed to be caffeic acid which had inhibitory effect on renal failure in mice by Ac1-P.
(15) In four main regions the conservation varied from 83-91% while in the remaining regions the homology dropped to between 56-62%.
(16) In the caudal spinal trigeminal nucleus (Vc), the collaterals of one half of the periodontium afferent fibers terminated mainly in lamina V at the rostral and middle levels of Vc.
(17) Loratadine has one main metabolite, descarbethoxyloratadine, which is four times more active than the parent drug.
(18) The structures of 1 and 2 were established mainly on the basis of nmr spectroscopic data.
(19) The main clinical symptom was pain, usually sciatica, while neurological symptoms were less common than they are in adults.
(20) Possibilities to achieve this both in the curative and the preventive field are restricted mainly due to the insufficient knowledge of their etiopathogenesis.