(a.) Having the form of a cross; appertaining to a cross; cruciform; intersecting; as, crucial ligaments; a crucial incision.
(a.) Severe; trying or searching, as if bringing to the cross; decisive; as, a crucial test.
Example Sentences:
(1) Therefore, the measurement of the alpha-antitrypsin content plays the crucial part in differential diagnosis of primary (hereditary determined) and secondary (obstructive) emphysema.
(2) At first it looked as though the winger might have shown too much of the ball to the defence, yet he managed to gain a crucial last touch to nudge it past Phil Jones and into the path of Jerome, who slipped Chris Smalling’s attempt at a covering tackle and held off Michael Carrick’s challenge to place a shot past an exposed De Gea.
(3) The agriculture ministry raised the risk level of the virus spreading from moderate to high on Tuesday across the country, at a crucial time for the industry.
(4) Conservative commentators responded with fury to what they believed was inappropriate meddling at a crucial moment in the town hall debate.
(5) Although the performance aspects of electronic displays are crucial considerations in workstation design, experience suggests that human factors in mechanical operation, software accessibility, and workstation environment are also important.
(6) The secretary of state should work constructively with frontline staff and managers rather than adversarially and commit to no administrative reorganisation.” Dr Jennifer Dixon, chief executive, Health Foundation “It will be crucial that the next government maintains a stable and certain environment in the NHS that enables clinical commissioning groups (CCGs) to continue to transform care and improve health outcomes for their local populations.
(7) The results suggest that the ACTH-containing part of the hypothalamus around the PVH is crucially involved in the organization of grooming behaviour.
(8) A functional impairment of the amino acid transport systems at the level of the blood-brain barrier seems to play a crucial role in causing deleterious modifications of the synaptic neurotransmission in the central nervous system.
(9) The cerebral distribution and regulation of excitatory amino acid levels may play a crucial role in neuronal development.
(10) Imagining faces was also the only condition that led to an increase of activity in the left inferior occipital region which has been suggested by previous studies as being a crucial area for visual imagery.
(11) This is the most crucial issue of our time and the people must be heard, not criminalised."
(12) Therefore it is crucial to investigate the role of glucocorticoids in non-pituitary tumours and this requires an understanding of the molecular mechanisms involved in glucocorticoid inhibition of the normal POMC gene in the pituitary.
(13) The agreement, hailed as a "landmark" deal and a breakthrough by politicians and the green lobby alike, came before a crucial EU summit opening in Brussels tomorrow at which 27 prime ministers and presidents are supposed to finalise an ambitious package to cut greenhouse gas emissions by 20% by 2020.
(14) A comparison of the pharmacokinetics as well as the teratogenicity between cyclophosphamide and some specific deuterium-labeled analogues showed that the isotope effect observed can be related to a particular metabolic pathway crucial for teratogenic activation by this drug.
(15) The crucial issue of whether subtle behavioral, intellectual, and developmental impairment occurs in young children, as a result of lead-induced CNS damage is discussed in detail.
(16) The crucial point in all likelihood is the nature of this heme-binding protein.
(17) Standard criteria for staging and response evaluation, including pathologic documentation of remission status, are crucial.
(18) Given that a post-poll economy still registers as a crucial issue among undecided voters, and that matters economic are now his BBC day job, that was hardly surprising.
(19) Overall, these results confirm that the medial septum plays a crucial role in the acquisition of problem solving.
(20) He is joined by Cathy O’Toole, the ALP candidate for the crucial swing seat of Herbert where Rudd’s campaign bus has stopped on Sunday evening.
Minor
Definition:
(a.) Inferior in bulk, degree, importance, etc.; less; smaller; of little account; as, minor divisions of a body.
(a.) Less by a semitone in interval or difference of pitch; as, a minor third.
(n.) A person of either sex who has not attained the age at which full civil rights are accorded; an infant; in England and the United States, one under twenty-one years of age.
(n.) The minor term, that is, the subject of the conclusion; also, the minor premise, that is, that premise which contains the minor term; in hypothetical syllogisms, the categorical premise. It is the second proposition of a regular syllogism, as in the following: Every act of injustice partakes of meanness; to take money from another by gaming is an act of injustice; therefore, the taking of money from another by gaming partakes of meanness.
(n.) A Minorite; a Franciscan friar.
Example Sentences:
(1) The significance of minor increases in the serum creatinine level must be recognized, so that modifications of drug therapy can be made and correction of possibly life-threatening electrolyte imbalances can be undertaken.
(2) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(3) Electronmicroscopical investigations have revealed that, under normal conditions, a minor vesicular transfer of intravenously injected peroxidase occurs across the endothelium in segments of arterioles, capillaries and venules, especially in arterioles with a diameter about 15-30 mu.
(4) Despite a 10-year deadline to have the same number of ethnic minority officers in the ranks as in the populations they serve, the target was missed and police are thousands of officers short.
(5) These sequences are also conserved in the same arrangement in minor sequence classes of minicircles from this strain.
(6) 2,3-Dihydroxybenzamide had previously been detected only as a minor metabolite of salicylamide by paper chromatography.
(7) The screening of blood products for HTLV-1 is of minor importance.
(8) Ligaments played a very minor role in the lifts studied.
(9) Although chronologic age may not be a good predictor of pregnancy outcome, adolescents remain a high-risk group due to factors which are more common among them such as biologic immaturity, inadequate prenatal care, poverty, minority status, and low prepregnancy weight, and because factors associated with an early adolescent pregnancy, such as low gynecologic age, may continue to influence the outcome of subsequent pregnancies.
(10) Our study suggests that a major part of the renal antimineralocorticoid activity of spironolactone may be attributable to minor sulfur-containing metabolites or their precursors having a high renal clearance that affords access to their site of activity via the renal tubular fluid.
(11) Overt hemorrhage, major or minor, was assessed clinically.
(12) Quality evaluations by usual human spermiogram methods were applicable with only minor modifications to the procedures.
(13) These results might help to explain why only a minority of individuals with a susceptible HLA type develop uveitis, as well as the variable incidence of disease in HLA-identical populations of different ethnic backgrounds.
(14) Normal rat soleus myosin has a major slow and a minor fast component due to two populations of muscle fibers.
(15) In his notorious 1835 Minute on Education , Lord Macaulay articulated the classic reason for teaching English, but only to a small minority of Indians: “We must do our best to form a class who may be interpreters between us and the millions whom we govern; a class of persons, Indians in blood and colour, but English in taste, in opinions, in morals and in intellect.” The language was taught to a few to serve as intermediaries between the rulers and the ruled.
(16) By applying this method to rat cardiac whole muscle, high-molecular weight proteins, such as myosin heavy chains, are focused on the first-dimensional gels and, in addition, minor components are resolved on the second-dimensional gels, without loss during equilibration with detergent.
(17) Amid all of the worry about her health, the difficult decisions around the surgery, and how to explain everything to the children, the practicalities of postponing the holiday was a relatively minor consideration.
(18) A relation between ejection fraction (EF) and the echo minor dimension measurements in end diastole and end systole was formulated, which permitted estimation of the EF from the echo measurements.
(19) Isometric exercise induces a significant shortening of both intervals although minor for QT so that the ratio significantly increases in comparison to baseline (p less than .001).
(20) The majority of the patients were Chinese (78.0%), followed by Malays (11.5%), Indians (8.1%) and other minority races (2.4%).