(a.) Having the form of a cross; appertaining to a cross; cruciform; intersecting; as, crucial ligaments; a crucial incision.
(a.) Severe; trying or searching, as if bringing to the cross; decisive; as, a crucial test.
Example Sentences:
(1) Therefore, the measurement of the alpha-antitrypsin content plays the crucial part in differential diagnosis of primary (hereditary determined) and secondary (obstructive) emphysema.
(2) At first it looked as though the winger might have shown too much of the ball to the defence, yet he managed to gain a crucial last touch to nudge it past Phil Jones and into the path of Jerome, who slipped Chris Smalling’s attempt at a covering tackle and held off Michael Carrick’s challenge to place a shot past an exposed De Gea.
(3) The agriculture ministry raised the risk level of the virus spreading from moderate to high on Tuesday across the country, at a crucial time for the industry.
(4) Conservative commentators responded with fury to what they believed was inappropriate meddling at a crucial moment in the town hall debate.
(5) Although the performance aspects of electronic displays are crucial considerations in workstation design, experience suggests that human factors in mechanical operation, software accessibility, and workstation environment are also important.
(6) The secretary of state should work constructively with frontline staff and managers rather than adversarially and commit to no administrative reorganisation.” Dr Jennifer Dixon, chief executive, Health Foundation “It will be crucial that the next government maintains a stable and certain environment in the NHS that enables clinical commissioning groups (CCGs) to continue to transform care and improve health outcomes for their local populations.
(7) The results suggest that the ACTH-containing part of the hypothalamus around the PVH is crucially involved in the organization of grooming behaviour.
(8) A functional impairment of the amino acid transport systems at the level of the blood-brain barrier seems to play a crucial role in causing deleterious modifications of the synaptic neurotransmission in the central nervous system.
(9) The cerebral distribution and regulation of excitatory amino acid levels may play a crucial role in neuronal development.
(10) Imagining faces was also the only condition that led to an increase of activity in the left inferior occipital region which has been suggested by previous studies as being a crucial area for visual imagery.
(11) This is the most crucial issue of our time and the people must be heard, not criminalised."
(12) Therefore it is crucial to investigate the role of glucocorticoids in non-pituitary tumours and this requires an understanding of the molecular mechanisms involved in glucocorticoid inhibition of the normal POMC gene in the pituitary.
(13) The agreement, hailed as a "landmark" deal and a breakthrough by politicians and the green lobby alike, came before a crucial EU summit opening in Brussels tomorrow at which 27 prime ministers and presidents are supposed to finalise an ambitious package to cut greenhouse gas emissions by 20% by 2020.
(14) A comparison of the pharmacokinetics as well as the teratogenicity between cyclophosphamide and some specific deuterium-labeled analogues showed that the isotope effect observed can be related to a particular metabolic pathway crucial for teratogenic activation by this drug.
(15) The crucial issue of whether subtle behavioral, intellectual, and developmental impairment occurs in young children, as a result of lead-induced CNS damage is discussed in detail.
(16) The crucial point in all likelihood is the nature of this heme-binding protein.
(17) Standard criteria for staging and response evaluation, including pathologic documentation of remission status, are crucial.
(18) Given that a post-poll economy still registers as a crucial issue among undecided voters, and that matters economic are now his BBC day job, that was hardly surprising.
(19) Overall, these results confirm that the medial septum plays a crucial role in the acquisition of problem solving.
(20) He is joined by Cathy O’Toole, the ALP candidate for the crucial swing seat of Herbert where Rudd’s campaign bus has stopped on Sunday evening.
Necessary
Definition:
(a.) Such as must be; impossible to be otherwise; not to be avoided; inevitable.
(a.) Impossible to be otherwise, or to be dispensed with, without preventing the attainment of a desired result; indispensable; requiste; essential.
(a.) Acting from necessity or compulsion; involuntary; -- opposed to free; as, whether man is a necessary or a free agent is a question much discussed.
(n.) A thing that is necessary or indispensable to some purpose; something that one can not do without; a requisite; an essential; -- used chiefly in the plural; as, the necessaries of life.
(n.) A privy; a water-closet.
(n.) Such things, in respect to infants, lunatics, and married women, as are requisite for support suitable to station.
Example Sentences:
(1) Apparently, the irradiation with visible light of a low intensity creates an additional proton gradient and thus stimulates a new replication and division cycle in the population of cells whose membranes do not have delta pH necessary for the initiation of these processes.
(2) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
(3) Intravesical BCG is clearly superior to oral BCG, and controlled studies have demonstrated that percutaneous administration is not necessary.
(4) These studies show that metabolic activation is necessary for the expression of the mutagenic activity of aflatoxins B1 and G1 in N. crassa.
(5) In practice, however, the necessary dosage is difficult to predict.
(6) In order to control noise- and vibration-caused diseases it was necessary not only to improve machines' quality and service conditions but also to pay special attention to the choice of operators and to the quality of monitoring their adaptation process.
(7) It is likely that trunk mobility is necessary to maintain integrity of SI joint and that absence of such mobility compromises SI joint structure in many paraplegics.
(8) If there is a will to use primary Care centres for effective preventive action in the population as a whole, motivation of the professionals involved and organisational changes will be necessary so as not to perpetuate the law of inverse care.
(9) Obamacare price hikes show that now is the time to be bold | Celine Gounder Read more No longer able to keep patients off their plans outright, insurers have resorted to other ways to discriminate and avoid paying for necessary treatments.
(10) Duesberg contends that HIV is neither necessary nor sufficient to cause AIDS.
(11) It is therefore necessary, to look at typical clinical manifestations, i.e.
(12) We have examined the in vitro membrane assembly characteristics of a variety of leader peptidase mutants and found that domains required for insertion in vivo are also necessary for insertion in vitro.
(13) Two hours after the administration, the combinations of ethanol plus diazepam and ethanol plus meclophenoxate impaired significantly the number of necessary repetitions.
(14) The first experiment gave good results, although only one participant had any previous experience of hinge axis location, and it is debatable whether or not this experience is necessary before satisfactory results can be obtained.
(15) For consistent identification of the normal pancreas, preliminary longitudinal scanning at, or near, the mid-line and subsequent oblique scanning in the long axis are necessary prerequisites in delineating the anatomic outline of the pancreas.
(16) Survival and healing of "extremely severe" grade intoxication can only be obtained through a surgical intervention within the first hours; a laparotomy will indicate the depth of the lesions, which is not determined by endoscopy, and will consist of Celerier's stripping method and if necessary a gastrectomy, more seldom a cephalic duodeno-pancreatectomy.
(17) Socio-economic improvement or behavioural changes appear necessary for the control of trachoma in endemic areas.
(18) This stimulation is mediated by one receptor with an apparent affinity of 3.3 X 10(-6) M. The hydroxyl group in the para position on phenylethanolamine was absolutely necessary to obtain an agonist whereas the meta hydroxyl group or the presence of a catechol almost suppressed the activity.
(19) Provided that adequate reflection is given and the appropriate moment chosen, it is well tolerated and provides all the necessary information.
(20) Total excisional biopsy is necessary to properly assess an adenoma microscopically.