(superl.) In its natural state; not cooked or prepared by fire or heat; undressed; not altered, refined, or prepared for use by any artificial process; raw; as, crude flesh.
(superl.) Unripe; not mature or perfect; immature.
(superl.) Not reduced to order or form; unfinished; not arranged or prepared; ill-considered; immature.
(superl.) Undigested; unconcocted; not brought into a form to give nourishment.
(superl.) Having, or displaying, superficial and undigested knowledge; without culture or profundity; as, a crude reasoner.
(superl.) Harsh and offensive, as a color; tawdry or in bad taste, as a combination of colors, or any design or work of art.
Example Sentences:
(1) Life expectancy and the infant mortality rate are considered more useful from an operational perspective and for comparisons than is the crude death rate because they are not influenced by age structure.
(2) While the reduced form of the "derived" polyphenolic compounds, generated during tissue homogenization, appeared to enhance dye binding with bovine serum albumin, their influence on the protein assay directly in crude homogenates was extremely diverse.
(3) Slight cross-reactivity was apparent when crude preparations of cellular or culture filtrate antigens, used in this laboratory to detect antibodies to Candida albicans, Coccidioides immitis and Cryptococcus neoformans, were probed with hyperimmune rabbit antisera to A. fumigatus.
(4) The crude survival rate at 5 years was 83.3% (age-adjusted 96%), and at 10 years 53.8%).
(5) VS had a crude topography, and receptive fields of neurons in VS were relatively large.
(6) With [125I-Tyr11]SRIF as a radiolabeled ligand, the specific ligand binding to crude membrane increased transiently in the early phase of postnatal development and then decreased.
(7) Dialyzed crude enzyme extracts from yeast cells were found to destroy diacetyl in a manner quite similar to that of diacetyl reductase from Aerobacter aerogenes, and both the bacterial and the yeast extracts were stimulated significantly by the addition of reduced nicotinamide adenine dinucleotide (NADH).
(8) A crude extract of Brucella melitensis was obtained by sonication, centrifugation and dialysis, and analyzed by quantitative immunoelectrophoresis.
(9) These results indicate that countercurrent distribution of crude extracts in aqueous two-phase systems is a useful method to study protein-protein interaction.
(10) Optimal myocyte cultures were obtained using serial 0.2% crude trypsin digestions of hearts from 1-2-day-old rats.
(11) Their defect in DNA degradation was shown not only after treatment by toluene but also in crude extracts after cell disintegration by ultrasonic and in untreated starved cultures.
(12) On subfractionation of this crude mitochondrial fraction with continuous sucrose density gradients, most of the activity of the three enzymes was found at a higher density than NAD+-isocitrate dehydrogenase and at about the same density as glutamate dehydrogenase, confirming earlier reported data for acetyl-CoA synthase.
(13) A crude membrane fraction derived from the mutant is unable to synthesize cardiolipin from phosphatidylglycerol in vitro.
(14) DNA membrane complexes from sucrose gradients, as well as the crude M-band preparation and a non-membrane-associated DNA fraction from nuclei can synthesize DNA in vitro without the addition of an external DNA template or DNA polymerase.
(15) Specificity of [125I]hCG binding to other tissues was determined by incubating crude membrane preparations of heart, skeletal muscle, liver, and kidney.
(16) Binding experiments of cyclic AMP on crude extract of dog thyroid lead to the conclusion that the maximal capacity of the specific binding site is close to the cyclic AMP content in resting thyroid cells.
(17) Interaction between these acceptor sites and crude or partially purified estradiol receptor shows a high association constant (over 10(9) M).
(18) The extent of sialomucin adjacent to a primary colorectal cancer does provide a crude assessment of tumour invasiveness and risk of local recurrence.
(19) Effects of 4-aminomethyl-1-benzylpyrrolidin-2-one-hemifumarate (WEB 1881 FU), a novel pyrrolidinone nootropic, on acetylcholine (ACh) receptors and adrenoceptors were investigated using crude membranes of the rat brain.
(20) By immunoaffinity chromatography using the immunoadsorbent, approximately 25% of crude enterotoxin applied was recovered in the eluate.
Cruel
Definition:
(n.) See Crewel.
(a.) Disposed to give pain to others; willing or pleased to hurt, torment, or afflict; destitute of sympathetic kindness and pity; savage; inhuman; hard-hearted; merciless.
(a.) Causing, or fitted to cause, pain, grief, or misery.
(a.) Attended with cruetly; painful; harsh.
Example Sentences:
(1) China’s new law also restricts the right of media to report on details of terror attacks, including a provision that media and social media cannot report on details of terror activities that might lead to imitation, nor show scenes that are “cruel and inhuman”.
(2) Through small and large acts of deprivation and destruction we follow the process: the removal of hope, of dignity, of luxury, of necessity, of self; the reduction of a man to a hoarder of grey slabs of bread and the scrapings of a soup bowl (wonderfully told all this, with a novelist's gift for detail and sometimes very nearly comic surprise), to the confinement of a narrow bed – in which there is "not even any room to be afraid" – with a stranger who doesn't speak your language, to the cruel illogicality of hating a fellow victim of oppression more than you hate the oppressor himself – one torment following another, and even the bleak comfort of thinking you might have touched rock bottom denied you as, when the most immediate cause of a particular stress comes to an end, "you are grievously amazed to see that another one lies behind; and in reality a whole series of others".
(3) It goes on: "In a reality of ongoing occupation, of solid cynicism and meanness, each and every one of us bears the moral obligation to try to relieve the suffering, do something to bend back the occupation's giant, cruel hand."
(4) At one point, Walters speculates that “she looks the same weight as the Duchess – about 8st”; later, he disingenuously asks her to discuss “the cruel comments about being a ‘childless spinster’”, neither telling readers who made those “cruel comments” in the first place, or where.
(5) More here: UK regulator urges banks to speed up swaps mis-selling compensation 8.40am GMT More reaction to the decision to send riot police to evict people from the offices of Greece's former state broadcaster this morning , starting with journalist Nick Malkoutzis: Nick Malkoutzis (@NickMalkoutzis) 5 mths after flicking switch on public broadcaster ERT, gov't tries to settle issue by sending riot police to remove remaining staff #Greece November 7, 2013 Nick Malkoutzis (@NickMalkoutzis) While #ERT will be off air for good after police intervention, the stain of how its closure has been handled won't wash away easily #Greece November 7, 2013 Lady Mondegreen (@amaenad) Like a mean stupid dog appeasing a cruel master, the Greek government wants to lay ERT's limp body at the troika's feet.
(6) The government confirmed on Tuesday that the second year of the cull had begun, sparking outrage from animal rights activists, campaigners and opposition politicians who claim it is cruel and ineffective.
(7) Her friends have been arrested and subjected to what they describe as cruel and inhumane treatment .
(8) The jury decided unanimously Thursday that the Colorado attack was cruel enough to justify the death penalty .
(9) One of its board members is retired Major General Andrew James “Jim” Molan, co-architect of Tony Abbott’s “Operation Sovereign Borders,” the draconian program relying on the remote island detention centres condemned as cruel and inhumane by multiple respected human rights organisations.
(10) MOAB map “Isis were so cruel to us,” said Ahmad.
(11) Philip French championed Boyle's career from the outset, describing his debut feature film, Shallow Grave , as "a good piece of storytelling... Hitchcock would have admired its ruthlessness and cruel humour."
(12) S an Francisco is now a cruel place and a divided one.
(13) In a rather florid letter with classical, literary and historical references, he told her: "You, I already know from happy experience, will not be cruel to my tender flame … As I think of you I shall learn to love you more.
(14) Of course the timing was cruel, aimed at throwing the prime minister off balance just before what turned out to be a fairly successful Commons question time.
(15) He could be very charming, he could be very cruel, but he mattered and he put something together that was extraordinary."
(16) One of the first demands is that the bombardments by the regime and its [Russian] backers must end.” Merkel condemned the air raids on Syria’s second city as “inhumane and cruel”.
(17) While Liverpool seemed stretched by cruel successive away fixtures, Chelsea arguably mustered some of their finest attacking football of the campaign through that ferocious opening period.
(18) If you follow Twitter regularly, it's easy to believe that many of our fellow citizens are cruel, mean, misogynist and foul-mouthed.
(19) We perceive the circumstances of our youth as normal and unexceptional, however sparse or cruel they may be.
(20) "It's outrageous and cruel that people are taken off to detention and the families hear nothing until the body shows up with signs of abuse," said Joe Stork, deputy Middle East director at Human Rights Watch.