(superl.) In its natural state; not cooked or prepared by fire or heat; undressed; not altered, refined, or prepared for use by any artificial process; raw; as, crude flesh.
(superl.) Unripe; not mature or perfect; immature.
(superl.) Not reduced to order or form; unfinished; not arranged or prepared; ill-considered; immature.
(superl.) Undigested; unconcocted; not brought into a form to give nourishment.
(superl.) Having, or displaying, superficial and undigested knowledge; without culture or profundity; as, a crude reasoner.
(superl.) Harsh and offensive, as a color; tawdry or in bad taste, as a combination of colors, or any design or work of art.
Example Sentences:
(1) Life expectancy and the infant mortality rate are considered more useful from an operational perspective and for comparisons than is the crude death rate because they are not influenced by age structure.
(2) While the reduced form of the "derived" polyphenolic compounds, generated during tissue homogenization, appeared to enhance dye binding with bovine serum albumin, their influence on the protein assay directly in crude homogenates was extremely diverse.
(3) Slight cross-reactivity was apparent when crude preparations of cellular or culture filtrate antigens, used in this laboratory to detect antibodies to Candida albicans, Coccidioides immitis and Cryptococcus neoformans, were probed with hyperimmune rabbit antisera to A. fumigatus.
(4) The crude survival rate at 5 years was 83.3% (age-adjusted 96%), and at 10 years 53.8%).
(5) VS had a crude topography, and receptive fields of neurons in VS were relatively large.
(6) With [125I-Tyr11]SRIF as a radiolabeled ligand, the specific ligand binding to crude membrane increased transiently in the early phase of postnatal development and then decreased.
(7) Dialyzed crude enzyme extracts from yeast cells were found to destroy diacetyl in a manner quite similar to that of diacetyl reductase from Aerobacter aerogenes, and both the bacterial and the yeast extracts were stimulated significantly by the addition of reduced nicotinamide adenine dinucleotide (NADH).
(8) A crude extract of Brucella melitensis was obtained by sonication, centrifugation and dialysis, and analyzed by quantitative immunoelectrophoresis.
(9) These results indicate that countercurrent distribution of crude extracts in aqueous two-phase systems is a useful method to study protein-protein interaction.
(10) Optimal myocyte cultures were obtained using serial 0.2% crude trypsin digestions of hearts from 1-2-day-old rats.
(11) Their defect in DNA degradation was shown not only after treatment by toluene but also in crude extracts after cell disintegration by ultrasonic and in untreated starved cultures.
(12) On subfractionation of this crude mitochondrial fraction with continuous sucrose density gradients, most of the activity of the three enzymes was found at a higher density than NAD+-isocitrate dehydrogenase and at about the same density as glutamate dehydrogenase, confirming earlier reported data for acetyl-CoA synthase.
(13) A crude membrane fraction derived from the mutant is unable to synthesize cardiolipin from phosphatidylglycerol in vitro.
(14) DNA membrane complexes from sucrose gradients, as well as the crude M-band preparation and a non-membrane-associated DNA fraction from nuclei can synthesize DNA in vitro without the addition of an external DNA template or DNA polymerase.
(15) Specificity of [125I]hCG binding to other tissues was determined by incubating crude membrane preparations of heart, skeletal muscle, liver, and kidney.
(16) Binding experiments of cyclic AMP on crude extract of dog thyroid lead to the conclusion that the maximal capacity of the specific binding site is close to the cyclic AMP content in resting thyroid cells.
(17) Interaction between these acceptor sites and crude or partially purified estradiol receptor shows a high association constant (over 10(9) M).
(18) The extent of sialomucin adjacent to a primary colorectal cancer does provide a crude assessment of tumour invasiveness and risk of local recurrence.
(19) Effects of 4-aminomethyl-1-benzylpyrrolidin-2-one-hemifumarate (WEB 1881 FU), a novel pyrrolidinone nootropic, on acetylcholine (ACh) receptors and adrenoceptors were investigated using crude membranes of the rat brain.
(20) By immunoaffinity chromatography using the immunoadsorbent, approximately 25% of crude enterotoxin applied was recovered in the eluate.
Derogatory
Definition:
(a.) Tending to derogate, or lessen in value; expressing derogation; detracting; injurious; -- with from to, or unto.
Example Sentences:
(1) So again, they did what they had to and should do.” Aakjaer’s Facebook account also contained other derogatory references to eastern Europeans, a message of support for the right-wing Dansk Folkeparti’s views about border control and a photograph of six pigs with a caption: “It’s time to deploy our secret weapons against Islamists.” When Aakjaer was contacted by the Guardian in January, he said that he was not “a racist at all”.
(2) While those "close relation[s]" are not supposed to be passed on for watchlisting absent other "derogatory information", their data may be retained within TIDE for unspecified "analytic purposes".
(3) Dunham similarly opted for a snarky introduction, invoking Trump’s derogatory comments toward women the crowd: “I’m Lena Dunham and, according to Donald Trump, I’m like a two.” Both actors were early supporters of Clinton’s and stumped for her during the Democratic primary.
(4) Then there is the bedroom tax (it is always a good moment for an opposition when they make a derogatory label stick to a policy), which the Department for Work and Pensions estimates will affect 660,000 tenants.
(5) The few alluring aspect of these patients would signify the derogatory imago of a destroyed body, that does not be the mediator of the relationship to the other.
(6) Andy Gray, the Sky Sports presenter at the centre of a sexism storm following derogatory comments about a female official, has been sacked by the broadcaster in response to "new evidence of unacceptable and offensive behaviour".
(7) Wilson began hearing voices "saying derogatory things", telling him that he was finished and was going to die soon, a condition that continues to this day.
(8) The ASA said that the ads did not directly link the word "pussy" with women and so was not derogatory or sexist to women.
(9) Retrospective media analysis would probably show that the term welfare was used increasingly during the 1990s often in a derogatory manner – a 1993 Sunday Times splash about lone mothers being "wedded to welfare" being a typical example.
(10) I mean, it’s interesting; last year I was here there was a Ukip town councillor who said derogatory things about gay marriage, it was a national news story, it led on some of the BBC bulletins.
(11) The Conservative MP Tracey Crouch, who sits on Parliament's culture, media and sport select committee, told the Mirror, "It's disappointing at a time when he's trying to encourage more women to play football that he is using derogatory terminology."
(12) The players admitted to an exchange studded with offensive terms including "cunt", "fuck off" and "knobhead", plus derogatory personal comments, with Ferdinand referring to claims Terry had an affair with Vanessa Perroncel, the former partner of his ex-team-mate Wayne Bridge.
(13) Kathimerini has the details : Pulled up,,,for using derogatory language, Iliopoulos went further, condemning fellow MPs as "wretched sell-outs" and "goats".
(14) While in a separate exchange on Facebook, of which the Daily Mail has photographs, Edoardo called another fan a “moron” during a heated exchange and also used another derogatory term.
(15) Former footballer Stan Collymore has accused Twitter of not doing enough to combat illegal abuse on the network, during a week when he and the former gymnast Beth Tweddle have both been subjected to derogatory comments.
(16) Managers who are derogatory, angry, or arrogant find that confrontation is ineffective in motivating their staff to improve.
(17) They included derogatory messages about Smith as a Jew, the South Korean international Kim Bo-kyung, reportedly four other offensive texts, and a reference to Vincent Tan, Cardiff City’s Malaysian owner, as “the Chink”.
(18) Starting today, we’re taking a tougher stance on hateful, offensive and derogatory content,” Schindler says.
(19) While this is reflective of a wider societal problem , teachers can do their bit by cracking down on language when it is used in a derogatory or abusive way.
(20) Three hours after reading the text, 58 of the subjects were exposed to a non-factual, derogatory comment on the World Cup.