(superl.) In its natural state; not cooked or prepared by fire or heat; undressed; not altered, refined, or prepared for use by any artificial process; raw; as, crude flesh.
(superl.) Unripe; not mature or perfect; immature.
(superl.) Not reduced to order or form; unfinished; not arranged or prepared; ill-considered; immature.
(superl.) Undigested; unconcocted; not brought into a form to give nourishment.
(superl.) Having, or displaying, superficial and undigested knowledge; without culture or profundity; as, a crude reasoner.
(superl.) Harsh and offensive, as a color; tawdry or in bad taste, as a combination of colors, or any design or work of art.
Example Sentences:
(1) Life expectancy and the infant mortality rate are considered more useful from an operational perspective and for comparisons than is the crude death rate because they are not influenced by age structure.
(2) While the reduced form of the "derived" polyphenolic compounds, generated during tissue homogenization, appeared to enhance dye binding with bovine serum albumin, their influence on the protein assay directly in crude homogenates was extremely diverse.
(3) Slight cross-reactivity was apparent when crude preparations of cellular or culture filtrate antigens, used in this laboratory to detect antibodies to Candida albicans, Coccidioides immitis and Cryptococcus neoformans, were probed with hyperimmune rabbit antisera to A. fumigatus.
(4) The crude survival rate at 5 years was 83.3% (age-adjusted 96%), and at 10 years 53.8%).
(5) VS had a crude topography, and receptive fields of neurons in VS were relatively large.
(6) With [125I-Tyr11]SRIF as a radiolabeled ligand, the specific ligand binding to crude membrane increased transiently in the early phase of postnatal development and then decreased.
(7) Dialyzed crude enzyme extracts from yeast cells were found to destroy diacetyl in a manner quite similar to that of diacetyl reductase from Aerobacter aerogenes, and both the bacterial and the yeast extracts were stimulated significantly by the addition of reduced nicotinamide adenine dinucleotide (NADH).
(8) A crude extract of Brucella melitensis was obtained by sonication, centrifugation and dialysis, and analyzed by quantitative immunoelectrophoresis.
(9) These results indicate that countercurrent distribution of crude extracts in aqueous two-phase systems is a useful method to study protein-protein interaction.
(10) Optimal myocyte cultures were obtained using serial 0.2% crude trypsin digestions of hearts from 1-2-day-old rats.
(11) Their defect in DNA degradation was shown not only after treatment by toluene but also in crude extracts after cell disintegration by ultrasonic and in untreated starved cultures.
(12) On subfractionation of this crude mitochondrial fraction with continuous sucrose density gradients, most of the activity of the three enzymes was found at a higher density than NAD+-isocitrate dehydrogenase and at about the same density as glutamate dehydrogenase, confirming earlier reported data for acetyl-CoA synthase.
(13) A crude membrane fraction derived from the mutant is unable to synthesize cardiolipin from phosphatidylglycerol in vitro.
(14) DNA membrane complexes from sucrose gradients, as well as the crude M-band preparation and a non-membrane-associated DNA fraction from nuclei can synthesize DNA in vitro without the addition of an external DNA template or DNA polymerase.
(15) Specificity of [125I]hCG binding to other tissues was determined by incubating crude membrane preparations of heart, skeletal muscle, liver, and kidney.
(16) Binding experiments of cyclic AMP on crude extract of dog thyroid lead to the conclusion that the maximal capacity of the specific binding site is close to the cyclic AMP content in resting thyroid cells.
(17) Interaction between these acceptor sites and crude or partially purified estradiol receptor shows a high association constant (over 10(9) M).
(18) The extent of sialomucin adjacent to a primary colorectal cancer does provide a crude assessment of tumour invasiveness and risk of local recurrence.
(19) Effects of 4-aminomethyl-1-benzylpyrrolidin-2-one-hemifumarate (WEB 1881 FU), a novel pyrrolidinone nootropic, on acetylcholine (ACh) receptors and adrenoceptors were investigated using crude membranes of the rat brain.
(20) By immunoaffinity chromatography using the immunoadsorbent, approximately 25% of crude enterotoxin applied was recovered in the eluate.
Primitive
Definition:
(a.) Of or pertaining to the beginning or origin, or to early times; original; primordial; primeval; first; as, primitive innocence; the primitive church.
(a.) Of or pertaining to a former time; old-fashioned; characterized by simplicity; as, a primitive style of dress.
(a.) Original; primary; radical; not derived; as, primitive verb in grammar.
(n.) An original or primary word; a word not derived from another; -- opposed to derivative.
Example Sentences:
(1) Cloacal exstrophy, centered on the maldevelopment of the primitive streak mesoderm and cloacal membrane, results in bladder and intestinal exstrophy, omphalocele, gender confusion, and hindgut deformity.
(2) Evx-1 RNA is first detected shortly before the onset of gastrulation in a region of ectoderm containing cells that will soon be found in the primitive streak.
(3) As an extension of the previous study which indicated that mesoglea is a primitive basement membrane which has retained some characteristics of interstitial extracellular matrix, the present study was undertaken to analyze the role of mesoglea components during head regeneration in Hydra vulgaris.
(4) neuroblastomas, primitive neuroectodermal tumours (PNETs), rhabdomyosarcomas and malignant lymphomas.
(5) We concluded that the primitive eukaryote D.discoideum contains proteins which show functional and physical similarity with the alpha-subunits of vertebrate G-proteins.
(6) Mechanisms are suggested whereby rudimentary appetitive programs already encoded along facing dendrite membrane pairs within the specialized intrafascicular milieu, may trigger and control nipple search and suckling in the still blind and only primitively mobile neonate.
(7) Thus, the progeny of infected primitive multipotential cells are competent to express integrated proviruses.
(8) Multiple tuberculomas have simulated either an alcoolic encephalopathy in one case or a primitive cerebral tumour in another one.
(9) This increased cell flow down the early stages of the red cell pathway in CML suggests that heightened proliferation and differentiation of primitive hemopoietic cells may be a more general phenomenon than previously suspected in this disease.
(10) The Lerner & Lerner Scale for assessing primitive defenses is reviewed.
(11) Only tumors of astrocytic lineage like astrocytomas and glioblastomas, or tumors of mixed lineage as oligo-astrocytomas and multipotential primitive neuroectodermal tumors (PNET) expressed TNF-alpha-like immunoreactivity.
(12) This epithelial cell was tentatively identified as primitive extraembryonic endoderm by its ultrastructural appearance and its possession of cytokeratin intermediate filaments.
(13) The long-term culture corresponded to mouse MXT and MCF-7 cell lines whereas the primary culture corresponded to primitive breast cancers squashed onto histologic slides and maintained in cultures for between 12 and 48 h. Cell proliferation was evaluated by means of digital cell image analysis of Feulgen-stained nuclei.
(14) From these facts, it was concluded that the follicular, as well as acanthomatous, ameloblastoma is liable to undergo squamous differentiation, whereas the plexiform ameloblastoma remains in primitive stage of tumor differentiation.
(15) A cluster of spermatogonia may be derived from one primitive germ cell and it develops round a "Sertoli" cell.
(16) Shielded marrow self renewal capacity, a measurement reflecting primitive hematopoietic stem cell function, remained depressed and did not recover with time.
(17) In a 3-year-old child, a rare combination of a Dandy-Walker syndrome, a primitive trigeminal artery and a facial haemangioma was found.
(18) As the histochemical and ultrastructural findings are non specific, we believe, according to recent opinions, that this tumor could originate in a very primitive cell, able to differentiate to endocrine or exocrine elements, almost always incompletely.
(19) It is likely that the development of these malignancies is an expression of the multipotential nature of primitive germ cells.
(20) Morphology of the mature spermatozoon is modified from that of the classic primitive or ect-aquasperm type by having 1) the acrosome embedded in the nucleus (the only known example within the Mollusca), 2) a deep basal invagination in the nucleus containing proximal and distal centrioles and an enveloping matrix (derived from the rootlet), 3) laterally displaced periaxonemal mitochondria, and 4) a tail extending from the basal invagination of the nucleus.