(superl.) In its natural state; not cooked or prepared by fire or heat; undressed; not altered, refined, or prepared for use by any artificial process; raw; as, crude flesh.
(superl.) Unripe; not mature or perfect; immature.
(superl.) Not reduced to order or form; unfinished; not arranged or prepared; ill-considered; immature.
(superl.) Undigested; unconcocted; not brought into a form to give nourishment.
(superl.) Having, or displaying, superficial and undigested knowledge; without culture or profundity; as, a crude reasoner.
(superl.) Harsh and offensive, as a color; tawdry or in bad taste, as a combination of colors, or any design or work of art.
Example Sentences:
(1) Life expectancy and the infant mortality rate are considered more useful from an operational perspective and for comparisons than is the crude death rate because they are not influenced by age structure.
(2) While the reduced form of the "derived" polyphenolic compounds, generated during tissue homogenization, appeared to enhance dye binding with bovine serum albumin, their influence on the protein assay directly in crude homogenates was extremely diverse.
(3) Slight cross-reactivity was apparent when crude preparations of cellular or culture filtrate antigens, used in this laboratory to detect antibodies to Candida albicans, Coccidioides immitis and Cryptococcus neoformans, were probed with hyperimmune rabbit antisera to A. fumigatus.
(4) The crude survival rate at 5 years was 83.3% (age-adjusted 96%), and at 10 years 53.8%).
(5) VS had a crude topography, and receptive fields of neurons in VS were relatively large.
(6) With [125I-Tyr11]SRIF as a radiolabeled ligand, the specific ligand binding to crude membrane increased transiently in the early phase of postnatal development and then decreased.
(7) Dialyzed crude enzyme extracts from yeast cells were found to destroy diacetyl in a manner quite similar to that of diacetyl reductase from Aerobacter aerogenes, and both the bacterial and the yeast extracts were stimulated significantly by the addition of reduced nicotinamide adenine dinucleotide (NADH).
(8) A crude extract of Brucella melitensis was obtained by sonication, centrifugation and dialysis, and analyzed by quantitative immunoelectrophoresis.
(9) These results indicate that countercurrent distribution of crude extracts in aqueous two-phase systems is a useful method to study protein-protein interaction.
(10) Optimal myocyte cultures were obtained using serial 0.2% crude trypsin digestions of hearts from 1-2-day-old rats.
(11) Their defect in DNA degradation was shown not only after treatment by toluene but also in crude extracts after cell disintegration by ultrasonic and in untreated starved cultures.
(12) On subfractionation of this crude mitochondrial fraction with continuous sucrose density gradients, most of the activity of the three enzymes was found at a higher density than NAD+-isocitrate dehydrogenase and at about the same density as glutamate dehydrogenase, confirming earlier reported data for acetyl-CoA synthase.
(13) A crude membrane fraction derived from the mutant is unable to synthesize cardiolipin from phosphatidylglycerol in vitro.
(14) DNA membrane complexes from sucrose gradients, as well as the crude M-band preparation and a non-membrane-associated DNA fraction from nuclei can synthesize DNA in vitro without the addition of an external DNA template or DNA polymerase.
(15) Specificity of [125I]hCG binding to other tissues was determined by incubating crude membrane preparations of heart, skeletal muscle, liver, and kidney.
(16) Binding experiments of cyclic AMP on crude extract of dog thyroid lead to the conclusion that the maximal capacity of the specific binding site is close to the cyclic AMP content in resting thyroid cells.
(17) Interaction between these acceptor sites and crude or partially purified estradiol receptor shows a high association constant (over 10(9) M).
(18) The extent of sialomucin adjacent to a primary colorectal cancer does provide a crude assessment of tumour invasiveness and risk of local recurrence.
(19) Effects of 4-aminomethyl-1-benzylpyrrolidin-2-one-hemifumarate (WEB 1881 FU), a novel pyrrolidinone nootropic, on acetylcholine (ACh) receptors and adrenoceptors were investigated using crude membranes of the rat brain.
(20) By immunoaffinity chromatography using the immunoadsorbent, approximately 25% of crude enterotoxin applied was recovered in the eluate.
Simple
Definition:
(a.) Single; not complex; not infolded or entangled; uncombined; not compounded; not blended with something else; not complicated; as, a simple substance; a simple idea; a simple sound; a simple machine; a simple problem; simple tasks.
(a.) Plain; unadorned; as, simple dress.
(a.) Mere; not other than; being only.
(a.) Not given to artifice, stratagem, or duplicity; undesigning; sincere; true.
(a.) Artless in manner; unaffected; unconstrained; natural; inartificial;; straightforward.
(a.) Direct; clear; intelligible; not abstruse or enigmatical; as, a simple statement; simple language.
(a.) Weak in intellect; not wise or sagacious; of but moderate understanding or attainments; hence, foolish; silly.
(a.) Not luxurious; without much variety; plain; as, a simple diet; a simple way of living.
(a.) Humble; lowly; undistinguished.
(a.) Without subdivisions; entire; as, a simple stem; a simple leaf.
(a.) Not capable of being decomposed into anything more simple or ultimate by any means at present known; elementary; thus, atoms are regarded as simple bodies. Cf. Ultimate, a.
(a.) Homogenous.
(a.) Consisting of a single individual or zooid; as, a simple ascidian; -- opposed to compound.
(a.) Something not mixed or compounded.
(a.) A medicinal plant; -- so called because each vegetable was supposed to possess its particular virtue, and therefore to constitute a simple remedy.
(a.) A drawloom.
(a.) A part of the apparatus for raising the heddles of a drawloom.
(a.) A feast which is not a double or a semidouble.
(v. i.) To gather simples, or medicinal plants.
Example Sentences:
(1) The accumulation of lipids and enzymes such as simple estarase, lipase, beta-HDH, alpha-GDH and NADPH-reductase in those areas, suggests that lipids are not a simple excretory product.
(2) The effects of sessions, individual characteristics, group behavior, sedative medications, and pharmacological anticipation, on simple visual and auditory reaction time were evaluated with a randomized block design.
(3) A new and simple method of serotyping campylobacters has been developed which utilises co-agglutination to detect the presence of heat-stable antigens.
(4) The results of the evaluation confirm that most problems seen by first level medical personnel in developing countries are simple, repetitive, and treatable at home or by a paramedical worker with a few safe, essential drugs, thus avoiding unnecessary visits to a doctor.
(5) Blatter requires a two-thirds majority of the 209 voters to triumph in the opening round, with a simple majority required if it goes to a second round.
(6) Each profile is described by a simple sequence of band transitions (BT-sequence).
(7) A simple method for ultrarapid freezing of cell cultures in monolayers was developed.
(8) A simple method of selective catheterization of the superficial femoral artery (SFA) following antegrade puncture of the common femoral artery is described.
(9) Although the relative contributions of different fuels varies greatly in different organisms, in none is there a simple reliance on stored ATP.
(10) Even if it were not the case that police use a variety of tricks to keep recorded crime figures low, this data would still represent an almost meaningless measure of the extent of crime in society, for the simple reason that a huge proportion of crimes (of almost all sorts) have always gone unreported.
(11) The method of sonicating L3 and Mf fragment antigens used in this study is simple, and its results are easy to observe.
(12) Simple cells that are nearly equally dominated by each eye always exhibit strong phase-specific interaction.
(13) More evil than Clocky , the alarm clock that rolls away when you reach out to silence it, or the Puzzle Alarm , which makes you complete a simple puzzle before it'll go quiet, the Money Shredding Alarm Clock methodically destroys your cash unless you rouse yourself.
(14) When cultures were pulse labeled for 15 min and then incubated under chase conditions for 105 min, the amount of degraded collagen attained a value equal to approximately 20% of the amount synthesized during the labeling period; the data were fit with a simple exponential function that had a 40-min rise time and a 12-min lag time.
(15) Treatment was monitored by simple measurements, and it's toxicity proved to be scanty.
(16) The presence of a previously unreported dipeptide transport mechanism within blood leukocytes and the selective enrichment of the granule enzyme, DPPI, within cytotoxic effector cells of lymphoid or myeloid lineage appear to afford a unique mechanism for the targeting of immunotherapeutic reagents composed of simple dipeptide esters or amides.
(17) The design of a simple dynamic knee simulator is described.
(18) Simple interconversion cannot account for the changes in binding that occur upon adding GMP-PNP or removing magnesium, since the increase in [R2]t exceeds the decrease in [R1]t. Moreover, the apparent amount of high-affinity complex exhibits a biphasic dependence on the concentration of [3H]histamine; an increase at low concentrations is offset by a decrease that occurs at higher concentrations.
(19) A rapid and simple method has been developed for the nondestructive distinction between aflatoxin B1 and the feed antioxidant, ethoxyquin.
(20) The stimuli were two simple tones in experiment 1 and two tonal complexes in both experiments 2 and 3.