(n.) A crude, undigested, or unprepared state; rawness; unripeness; immatureness; unfitness for a destined use or purpose; as, the crudeness of iron ore; crudeness of theories or plans.
Example Sentences:
(1) Life expectancy and the infant mortality rate are considered more useful from an operational perspective and for comparisons than is the crude death rate because they are not influenced by age structure.
(2) While the reduced form of the "derived" polyphenolic compounds, generated during tissue homogenization, appeared to enhance dye binding with bovine serum albumin, their influence on the protein assay directly in crude homogenates was extremely diverse.
(3) Slight cross-reactivity was apparent when crude preparations of cellular or culture filtrate antigens, used in this laboratory to detect antibodies to Candida albicans, Coccidioides immitis and Cryptococcus neoformans, were probed with hyperimmune rabbit antisera to A. fumigatus.
(4) The crude survival rate at 5 years was 83.3% (age-adjusted 96%), and at 10 years 53.8%).
(5) VS had a crude topography, and receptive fields of neurons in VS were relatively large.
(6) With [125I-Tyr11]SRIF as a radiolabeled ligand, the specific ligand binding to crude membrane increased transiently in the early phase of postnatal development and then decreased.
(7) Dialyzed crude enzyme extracts from yeast cells were found to destroy diacetyl in a manner quite similar to that of diacetyl reductase from Aerobacter aerogenes, and both the bacterial and the yeast extracts were stimulated significantly by the addition of reduced nicotinamide adenine dinucleotide (NADH).
(8) A crude extract of Brucella melitensis was obtained by sonication, centrifugation and dialysis, and analyzed by quantitative immunoelectrophoresis.
(9) These results indicate that countercurrent distribution of crude extracts in aqueous two-phase systems is a useful method to study protein-protein interaction.
(10) Optimal myocyte cultures were obtained using serial 0.2% crude trypsin digestions of hearts from 1-2-day-old rats.
(11) Their defect in DNA degradation was shown not only after treatment by toluene but also in crude extracts after cell disintegration by ultrasonic and in untreated starved cultures.
(12) On subfractionation of this crude mitochondrial fraction with continuous sucrose density gradients, most of the activity of the three enzymes was found at a higher density than NAD+-isocitrate dehydrogenase and at about the same density as glutamate dehydrogenase, confirming earlier reported data for acetyl-CoA synthase.
(13) A crude membrane fraction derived from the mutant is unable to synthesize cardiolipin from phosphatidylglycerol in vitro.
(14) DNA membrane complexes from sucrose gradients, as well as the crude M-band preparation and a non-membrane-associated DNA fraction from nuclei can synthesize DNA in vitro without the addition of an external DNA template or DNA polymerase.
(15) Specificity of [125I]hCG binding to other tissues was determined by incubating crude membrane preparations of heart, skeletal muscle, liver, and kidney.
(16) Binding experiments of cyclic AMP on crude extract of dog thyroid lead to the conclusion that the maximal capacity of the specific binding site is close to the cyclic AMP content in resting thyroid cells.
(17) Interaction between these acceptor sites and crude or partially purified estradiol receptor shows a high association constant (over 10(9) M).
(18) The extent of sialomucin adjacent to a primary colorectal cancer does provide a crude assessment of tumour invasiveness and risk of local recurrence.
(19) Effects of 4-aminomethyl-1-benzylpyrrolidin-2-one-hemifumarate (WEB 1881 FU), a novel pyrrolidinone nootropic, on acetylcholine (ACh) receptors and adrenoceptors were investigated using crude membranes of the rat brain.
(20) By immunoaffinity chromatography using the immunoadsorbent, approximately 25% of crude enterotoxin applied was recovered in the eluate.
Rudeness
Definition:
Example Sentences:
(1) You need a little moleskine, to write rude ideas... Mel No, I’ve just started recycling them.
(2) I categorically never said that ‘Britain has so many paedophiles because it has so many Asian men’.” She added that it was “totally untrue” that she had threatened to “take this inquiry down with me”, and absolutely rejected being rude and abusive to junior staff.
(3) For a while yesterday, Hazel Blears's selfishly-timed resignation with her rude "rock the boat" brooch send shudders of revulsion through some in the party.
(4) Like low blood pressure after a heart attack, then, cheap oil should arguably be regarded not as a sign of rude health, but rather as a consequence of malaise.
(5) This country has had a free press for the last 300 years, that has been irreverent and rude as my website is and holding public officials to account.
(6) We had some memorable encounters and he was very rude to me.
(7) He privately told the privy counsellors' committee of inquiry set up to review the events leading up to the invasion: "If I may be very frank and rather rude, you had to keep the ball in the air with the Argentines.
(8) There will be dialogue and discussions about what works, rather than rude surprises that backfire.
(9) As Google states, it is definitely in the company’s best interest to get its first smartglass customers to behave, as “breaking the rules or being rude will not get businesses excited about Glass and will ruin it for other Explorers”.
(10) I think, in all honestly, if I could be Bradley Whitford I would be very, very happy.” He becomes almost drawlingly dreamy, rolling his “r”s as he leans against the warm oolite cliffs of this Jurassic Coast, until rudely interrupted by me, asking whether there’s talk of a Broadchurch 3 .
(11) If someone was rude to you, you were rude back to them.
(12) Brexiters face rude awakening on immigration, says ex-minister Read more The problem is, there is nothing on the horizon to suggest that achieving any significant reduction in immigration is achievable or even desirable.
(13) He repeatedly argued that his south London upbringing meant he was rude to people who were rude to him and said Jones needed to “get over it”, although he said that he was unaware of his colleague’s history of illness.
(14) When he sees what he's inherited, he may get a rude awakening.
(15) Having reassured ourselves that we’re justified in “holding them to account” and “having robust debates” and “speaking truth to power”, we’re now just flat-out rude to their faces?
(16) But the fact that there is a serious disagreement between Zimbabwe and the United Kingdom does not mean that you should then be discourteous or rude."
(17) I said to them afterwards: ‘If you’re not on it 100% in this league, you’ll get a rude awakening.’’” Albion must be sick of the sight of QPR and Charlie Austin in particular.
(18) I can think of hordes of politicians who look worse and "weirder", with wet little pouty-mouths, strange shiny skin, mad glaring eyes, deathly pale demeanour, blank gaze and an unhealthy quantity of fat (I can't name them, because it's rude to make personal remarks), and I don't hear anyone calling them "weird", or mocking their looks, except for the odd bold cartoonist, but when it comes to Miliband , it's be-as-rude-as-you-like time.
(19) She said something rude, and I picked up her arm and I bit it!
(20) So instead of asking for anything on her birthday, she gives her friends presents, and she regularly sticks bullies and rude policemen in trees.