(n.) Anything that is very puzzling or difficult to explain.
Example Sentences:
(1) Although the most common pattern is for the right coronary artery to bifurcate at the crux giving the posterior descending (posterior interventricular) artery, a branch may arise before the crux, either as an aberrant acute marginal artery or as an early posterior descending artery, crossing the diaphragmatic surface of the right ventricle.
(2) Kafala sponsorship system At the crux of the debate over how Qatar and its Gulf neighbours treat migrant workers, human rights groups have long called for the kafala system that ties workers to their employers to be abolished.
(3) The crux of the trisection strategy is to restrict attention to the smallest block of ordered loci among which the new locus can fall and to divide this block into thirds for the next comparison.
(4) Bidirectional continuous turbulent Doppler signals were detected in the proximal portions of the dilated right and left coronary arteries, in the distal portions of the fistulas around the crux and in the right atrium.
(5) The crux is that the culling proposed by the government is very different to that in the earlier £50m RBCT.
(6) But the crux of the rift among Republicans is what to do about the roughly 11 million undocumented immigrants living in the US.
(7) That said, yeah, I think both public and private perception that big powerful game consoles are still somehow the crux or core focus of videogames will go away over the next few years, but even with the Vita TV and iPad Whatever and Steamboxes, I don't see these cannibalising enough of the existing console audience to actually make these things go away.
(8) These views provide improved visualization of the proximal branches of the left coronary artery, the region of the crux of the right coronary artery, and the left ventricle in the left anterior oblique projection; structures which in the conventional projections are often superimposed on one another or are foreshortened.
(9) The Mistake Creek Massacre, an indigenous painting at the crux of Australia’s culture wars.
(10) The septum which separated it from the main chamber was directed to the crux of the heart.
(11) I would say take it out, but it forms the crux of the call and is VERY funny.
(12) "We've won it," came the crux of Tenenbaum's translation.
(13) The crux of Muñoz Marín’s ridiculously illogical argument – one cannot achieve “political freedom” and be “deadset against colonialism” when one is not “demanding independence” or “asking for statehood” – illustrates how the island’s mostly white, male and affluent political class never had a real vision for Puerto Ricans or Puerto Rico , even from the outset of Muñoz Marín’s failed “commonwealth” experiment that he sold his fellow boricuas .
(14) In other words, the crux of this tale isn't Toronto city council's softness, it's Toronto voters' wildcard craziness.
(15) Cynics may ask: “If it is that simple, why can it not happen all the time?” That for me is the crux of the matter.
(16) The mass media campaign was important, but the party says the crux of its strategy was face-to-face meetings, conversation-by-conversation.
(17) The crux of the matter is whether the virus recovered from or detected in the cornea is 1) truly latent in cell populations that are nonneuronal; 2) resident in the cornea, replicating at a slow rate; or 3) newly arrived in the cornea following ganglionic reactivation.
(18) ", the memo said: "In typical fashion, while the government of Libya's public criticism has comprised pseudo-populist rhetoric against "the forces of Zionism", the crux of the matter is in fact about personal relations and politics."
(19) Because estimates of recombination are different in each set of data, the crux of the problem is to present scores that provide a close approximation to the true likelihood away from maximum likelihood (ML).
(20) Finally, the distribution of blood vessels within the retina formed a watershed pattern with its crux centered on the ridge of this horizontally oriented high-density zone.
Difficulty
Definition:
(n.) The state of being difficult, or hard to do; hardness; arduousness; -- opposed to easiness or facility; as, the difficulty of a task or enterprise; a work of difficulty.
(n.) Something difficult; a thing hard to do or to understand; that which occasions labor or perplexity, and requires skill and perseverance to overcome, solve, or achieve; a hard enterprise; an obstacle; an impediment; as, the difficulties of a science; difficulties in theology.
(n.) A controversy; a falling out; a disagreement; an objection; a cavil.
(n.) Embarrassment of affairs, especially financial affairs; -- usually in the plural; as, to be in difficulties.
Example Sentences:
(1) Technical factors that account for increased difficulty in these patients include: problems with guide catheter impaction and ostial trauma; inability to inflate the balloon with adequate guide catheter support; and need for increased intracoronary manipulation.
(2) To overcome this difficulty, a "hetero-antibody" RIA was studied.
(3) Epidemiological studies on low risks involve a number of major methodological difficulties.
(4) Mild swallowing difficulties occurred in 18 patients (39%), moderate dysfunction in 23 (50%), and severe dysfunction in five (11%).
(5) Reasons for non-acceptance do not indicate any major difficulties in the employment of such staff in general practice, at least as far as the patients are concerned.
(6) Spontaneous reports of suspected adverse reactions may be the only way of revealing very rare events but they present great difficulties of rational interpretation.
(7) The indication of the DNA probe method would be considered in the four cases as follows, 1. necessity of the special equipment to isolate the pathogen, 2. necessity of the long period to isolate the pathogen, 3. existence of the cross reaction among the pathogen and relative organisms in the immunological procedure, 4. existence of the difficulty to identify the species of the pathogen by the ordinary procedure.
(8) The 1-0-methylalduronic-acidmethylesters, obtained by the methanolysis of the polysaccharides, are reduced with boronhydrid to the corresponding methyl glycosides; there are split with acid to the aldoses, which are converted in pyridine with hydroxylamine to the aldoximes and than with acetic anhydride to the aldonitrilacetates, which can be separated by gaschromatography without difficulty.
(9) A control experiment demonstrated that changes in general arousal could not account for the effects of task difficulty on neuronal responses.
(10) In the anatomy laboratory we looked for an alternative approach to the glenohumeral joint which would accommodate these difficulties.
(11) A 27-year-old lady presented with history of discomfort in the throat and difficulty in swallowing for two weeks.
(12) Especially in the old patients (over 70 years) the incisional hernias represents an invalidating pathology whose treatment, for the high incidence of associated diseases of respiratory and cardiocirculatory apparatus in the aged, offers difficulties connected both to surgical methods and to the perioperative evaluation and preparation of patients.
(13) Marked pain and great difficulty in introducing the apparatus made its use limited in respectively 15% and 14.5% of cases.
(14) The tasks which appeared to present the most difficulties for the patients were written spelling, pragmatic processing tasks like sentence disambiguation and proverb interpretation.
(15) In favorable cases, tRNA-DNA hybrids of length about 80 nucleotide pairs can be recognized (although with difficulty).
(16) The patient with the right posterior lesion could not recognize handwriting, was prosopagnosic and topographagnosic, but had no difficulty in reading, lipreading, or in recognizing stylized drawings.
(17) A review of the literature summarises the difficulties of diagnosis.
(18) The major difficulty encountered with the current technique is the danger of neurologic injury during the passage and handling of conventional wires, especially in extensive procedures.
(19) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(20) While mindful of the potential difficulties which attend its introduction into the treatment situation there is an attempt to balance this position through a consideration of the appropriate conditions and modes of operation under which a humor-enriched approach may be efficacious.