(n.) A vault wholly or partly under ground; especially, a vault under a church, whether used for burial purposes or for a subterranean chapel or oratory.
(n.) A simple gland, glandular cavity, or tube; a follicle; as, the crypts of Lieberk/hn, the simple tubular glands of the small intestines.
Example Sentences:
(1) The subcellular distribution of sialyltransferase and its product of action, sialic acid, was investigated in the undifferentiated cells of the rat intestinal crypts and compared with the pattern observed in the differentiated cells present in the surface epithelium.
(2) A comparative evaluation of these data suggest that hormone independent cells are present in the cervical crypts of late menopause women and that a cyclic change of hormone dependent cells may occur in fertile women, analogous to the cyclic changes of endometrial mucosa.
(3) The proliferating cells showing increased hybridization include normal mitotically active crypt epithelium, regenerating epithelium in ulcerative colitis, adenomatous epithelium, and adenocarcinomatous epithelium.
(4) There was also a reduced crypt cell proliferation, a reduced villus height and a decreased ALP activity in the ileal mucosa.
(5) Explants maintained villus-to-crypt ratio between 1:1 and 1.5:1 for 48 hours.
(6) The diameters of regenerating crypts were measured at various times after X-rays and cis-platinum given either alone or in combination.
(7) In both of these groups, the inoculated bacteria were recovered from the colon, and T hyodysenteriae was demonstrated in the colonic crypts, epithelium, and lamina propria.
(8) Succinylated wheat germ agglutinin bound more to crypt than to villus enterocytes.
(9) The crypts were studied at 1, 5, 7, 15 and 30 days after the initiation of treatment.
(10) Newborn animals already exhibited clearly recognizable crypts of Lieberkühn.
(11) In addition, we found that carbamoylphosphate synthetase mRNA is present mainly in the epithelium of the crypts of the proximal part of the small intestine, whereas carbamoylphosphate synthetase protein is present in the epithelium of both crypts and villi.
(12) The peptide toxin apamin inhibits Ca2(+)-activated K+ channels exclusively in surface cell vesicles, while charybdotoxin inhibits predominantly in the crypt cell membrane fraction.
(13) Intrinsic factor-mediated uptake of cobalamin could not be demonstrated using ileal crypt or jejunal villous or crypt cells.
(14) A method has been developed for the simultaneous isolation of basolateral plasma membrane vesicles from surface and crypt cells of rabbit distal colon epithelium by sequential use of differential sedimentation, isopycnic centrifugation and Ficoll 400 barrier centrifugation.
(15) In contrast, foci formed by 3-4 dysplastic crypts were decreased by the starch diet (P less than 0.05).
(16) In the former group the changes observed were mucosal oedema with acute inflammation of varying severity but with preservation of the crypt architecture.
(17) (ii) In young sucklings (10 days old), SC was virtually absent in both villus and crypt cells, but its concentration progressively increased in weanling rats and reached adult levels by day 40 postpartum.
(18) Sub-groups of 5-7 rats were sequentially killed at 4, 8 and 12 months for evaluation of the length, cell numbers and 5-bromo-2'-deoxyuridine (BrDU) labeling indices of large bowel crypts together with ODC activity.
(19) One of the conventional approaches used in the past provided estimates of about 70-80 clonogenic cells per crypt (i.e.
(20) Immunofluorescence studies employing monoclonal antibodies specific for villus and crypt cells in vivo, and various enzyme assays, have demonstrated a level of differentiation and maturation of the cultured epithelial cells similar but not identical to that of suckling intestinal mucosa in vivo.
Grave
Definition:
(v. t.) To clean, as a vessel's bottom, of barnacles, grass, etc., and pay it over with pitch; -- so called because graves or greaves was formerly used for this purpose.
(superl.) Of great weight; heavy; ponderous.
(superl.) Of importance; momentous; weighty; influential; sedate; serious; -- said of character, relations, etc.; as, grave deportment, character, influence, etc.
(superl.) Not light or gay; solemn; sober; plain; as, a grave color; a grave face.
(superl.) Not acute or sharp; low; deep; -- said of sound; as, a grave note or key.
(superl.) Slow and solemn in movement.
(n.) To dig. [Obs.] Chaucer.
(n.) To carve or cut, as letters or figures, on some hard substance; to engrave.
(n.) To carve out or give shape to, by cutting with a chisel; to sculpture; as, to grave an image.
(n.) To impress deeply (on the mind); to fix indelibly.
(n.) To entomb; to bury.
(v. i.) To write or delineate on hard substances, by means of incised lines; to practice engraving.
(n.) An excavation in the earth as a place of burial; also, any place of interment; a tomb; a sepulcher. Hence: Death; destruction.
Example Sentences:
(1) A reduction in neonatal deaths from this cause might be expected if facilities for antenatal diagnosis and termination of pregnancy were made available, although this raises grave ethical problems.
(2) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
(3) A patient with previously treated follicular carcinoma of the thyroid developed Graves' disease with a high titre of thyroid-stimulating antibodies (TSAb).
(4) Gwendolen Morgan, the lawyer at Bindmans dealing with the case, said: "We have grave concerns about the decision to use this draconian power to detain our client for nine hours on Sunday – for what appear to be highly questionable motives, which we will be asking the high court to consider.
(5) Superoxide dismutase (SOD) activity and its concentration were measured in thyroid tissues obtained from patients with Graves' disease, Hashimoto's thyroiditis, differentiated thyroid cancer, and endemic goiter (before and after iodine supplementation) as well as in normal thyroid tissue (paranodular tissue) from patients with follicular adenomas.
(6) Many reports of thyroid stimulating immunoglobulins (TSI) in relation to treatment of Graves' disease have been published and with variable results concerning prediction of permanent remission or relapse after therapy.
(7) The Duke and Duchess of Cambridge stood among the graves on 4 August last year in a moving ceremony to mark the 100th anniversary of the outbreak of war.
(8) After violence had run its bloody course, the country’s rulers conceded it had been a catastrophe that had brought nothing but “grave disorder, damage and retrogression”.
(9) On the other hand, immunofluorescence in anterior pituitary cells was faint and detected in only 2 of 28 patients with Graves' disease (7.1%) after absorption of their sera with rat liver aceton powder.
(10) In conclusion, not only TBII but also T3 release-stimulating antibodies may occur in a minority of patients with long-term remission of Graves' hyperthyroidism.
(11) It is deeply moving hearing him talk now – as if from the grave – about a Christmas Day when he felt so frustrated and cut-off from his family that he had to go into the office to escape.
(12) His verdict of her that "she danced on the graves of her husband's victims.
(13) Thirty-eight bodies have been removed from the mass graves, but DNA tests have shown that none is that of a missing student.
(14) Posterior synechiae, pupil deformations, grave uveitis with hypotonia of 4-10 mm Hg are rapidly developing.
(15) Displacement of [125I]TSH bound to fat cell membranes by both Graves' Ig and unlabeled TSH were time and temperature dependent, with similar dissociation curves, suggesting a specific binding of Graves' Ig to the membrane sites related to the TSH receptor in the fat cells.
(16) We have obtained sera from 42 patients with active Graves' disease and no known connective tissue disorders.
(17) A total of 5.8% abnormalities were found including nodular disease, thyroiditis, Graves' disease, hypothyroidism, simple goiter, and iatrogenic hyperthyroidism.
(18) LATS was measured with the double isotope technique in IgG serum concentrates of 23 patients with Graves' disease before treatment and of 18 patients during treatment with carbimazole and triiodothyronine.
(19) To elucidate whether insulin-induced hypoglycemia enhances the release of beta-endorphin in man, plasma extracts obtained from healthy subjects and patients with Graves' disease before and 45 min after insulin injection were subjected to gel chromatography, and the fractions obtained were measured by RIA for beta-endorphin.
(20) From the findings of abnormalities in intrathyroidal T cell subsets, we suggest that the decrease in the function of suppressor T cells within the thyroids of Graves' disease patients may be due to a decrease in CD4+2H4+ cells within thyroid tissue.