What's the difference between crystal and phencyclidine?

Crystal


Definition:

  • (n.) The regular form which a substance tends to assume in solidifying, through the inherent power of cohesive attraction. It is bounded by plane surfaces, symmetrically arranged, and each species of crystal has fixed axial ratios. See Crystallization.
  • (n.) The material of quartz, in crystallization transparent or nearly so, and either colorless or slightly tinged with gray, or the like; -- called also rock crystal. Ornamental vessels are made of it. Cf. Smoky quartz, Pebble; also Brazilian pebble, under Brazilian.
  • (n.) A species of glass, more perfect in its composition and manufacture than common glass, and often cut into ornamental forms. See Flint glass.
  • (n.) The glass over the dial of a watch case.
  • (n.) Anything resembling crystal, as clear water, etc.
  • (a.) Consisting of, or like, crystal; clear; transparent; lucid; pellucid; crystalline.

Example Sentences:

  • (1) Such a signal must be due to a small ferromagnetic crystal formed when the nerve is subjected to pressure, such as that due to mechanical injury.
  • (2) A comprehensive review of the roentgenographic features of calcium pyrophosphate crystal deposition disease (pseudogout) is presented.
  • (3) CW Nd:YAG light transmitted by fiber optic cable and sapphire crystal was applied transsclerally to the ciliary body of pigmented and albino rabbits.
  • (4) The crystal structure of the biological stain, "acridine orange," has been determined.
  • (5) Urinalysis revealed a low pH, increased ketones and bilirubin excretion, dark yellowish change in color, the appearance of "leaflet-shaped" crystals and increased red blood cells and epithelial cells in the urinary sediment, increased water intake, decreased specific gravity and decreased sodium, potassium and chloride in the urine.
  • (6) Early in the regression process, cholesterol esters are reduced at least partly by hydrolysis to yield cholesterol, some of which may crystallize and inhibit rapid regression.
  • (7) Here we determine the position of bound ADP diffused into the recA crystal.
  • (8) The virus material in these crystals had been subjected to treatment with EDTA at pH 8.0 before crystallization at pH 6.5.
  • (9) Results obtained show that chlorophyll is more active than other inhibitors studied and suggest a higher surface adsorption intensity on the primary sources of the crystal surface.
  • (10) The "Mg(2+)-Sarkosyl crystals" (M band) technique distinguishes between membrane-bound and free intracellular DNA.
  • (11) The molecular structure of the hexagonal crystal form of porcine pepsin (EC 3.4.23.1), an aspartic proteinase from the gastric mucosa, has been determined by molecular replacement using the fungal enzyme, penicillopepsin (EC 3.4.23.6), as the search model.
  • (12) In vitro experiments show that these macromolecules are able to interact with specific faces of different crystals, influencing both nucleation and crystal growth.
  • (13) 2 Each of the drugs significantly increased leucocyte cyclic AMP content within 3 h of the injection of crystals.
  • (14) For Kevin Phillips, just like Wilfried Zaha, this might have been his final act as a Crystal Palace player.
  • (15) In ancillary studies, multiple cycles of direct dissolution of UCB crystals revealed a progressive decrease in aqueous solubility of UCB as fine crystals were removed; this effect was minimal in CHCl3.
  • (16) Six dogs were instrumented with electromagnetic flow probes and subendocardial ultrasonic crystals.
  • (17) The crystallization of the lipase was successfully carried out.
  • (18) The values of the energy level distributions in crystals obtained from the measurements and analysis reported here are compared with those obtained by a different method for the same protein complex in frozen solution.
  • (19) The crystal structure of proteolytically modified human ACT has been solved at 2.7-A resolution (Baumann et al., 1991).
  • (20) These observations support our hypothesis that calcium pyrophosphate dihydrate crystal deposition in joints is regulated by the physical chemical gel state of the connective tissue matrix.

Phencyclidine


Definition:

Example Sentences:

  • (1) To test the hypothesis that EAA agonists are involved in transmission of nociceptive information in the spinal cord, we tested the effect of various opioid, sigma and phencyclidine compounds on the action of NMDA in the tail-flick, hot-plate and biting and scratching nociceptive tests.
  • (2) The increase probably reflects an inhibition of the re-uptake of released 3H-noradrenaline; in addition, phencyclidine appears to enhance the release of noradrenaline per pulse.--The actions of phencyclidine and ketamine on central noradrenergic neurones may contribute to the characteristic psychotropic side-effects of these general anaesthetics.
  • (3) The present experiments compared the noncompetitive N-methyl-D-aspartate antagonists phencyclidine and MK-801 with the anticonvulsant phenytoin in a model of focal brain ischemia.
  • (4) The neuronal localization of glutamate and phencyclidine (PCP) receptors was evaluated in the cerebral cortex and hippocampal formation of rat CNS using quantitative autoradiography.
  • (5) Emergency Room patients at Riverside General Hospital who are found by the attending physician to have depressed sensorium and altered personality are routinely subjected to urine tests for various drugs of abuse including phencyclidine (PCP).
  • (6) Phencyclidine (PCP) is a dissociative anesthetic agent which blocks the excitatory effect of N-methyl-D-aspartate (NMDA) in the central nervous system.
  • (7) Only the sigma agonist, phencyclidine, showed any capacity for blocking the PTZ stimulus.
  • (8) Drugs of the fentanyl series (4-anilino-piperidines) were potent displacers whereas agonists of the delta- (enkephalin derivatives), sigma- (phencyclidine, haloperidol, 3-hydroxyphenyl-propylpiperidine) or K- (U 50488) opiate sites had a low affinity (Ki greater than 0.5 microM) for 3H-lofentanil specific binding sites.
  • (9) Related compounds including [D-Ala2, D-Leu5]enkephalin (DADLE), n-allylnormetazocine and phencyclidine were also examined.
  • (10) Phencyclidine residues were found in the brains of rat pups of mothers dosed with this drug during pregnancy.
  • (11) For 15 unselected urines the concentrations of phencyclidine showed no significant correlation with urinary pH.
  • (12) However, at high doses, DTG selectively suppressed the potentiation induced by a low dose of DTG and reduced the NMDA response below base line, presumably due to its low affinity for phencyclidine sites.
  • (13) Phencyclidine, which is an indirect dopaminergic agonist in the caudate, caused inhibition of the discharges of caudate neurons resembling that induced by dopamine itself.
  • (14) Significantly more blunting of the response of TSH to TRH was shown in cocaine and phencyclidine abusers compared with that seen in controls.
  • (15) Recently, we reported the characterization of a selective sigma receptor ligand, 1,3-di-o-tolyl-guanidine (DTG), that shows negligible crossreactivity with phencyclidine receptors.
  • (16) Phencyclidine had a biphasic effect on overall response rates in both components: response rates increased and then decreased as the dose was increased.
  • (17) The effects of phencyclidine infusions on fixed-ratio responding were variable.
  • (18) One of the analogs, cis-2-hydroxymethyl-r-1-(N-piperidyl)-1-(2-thienyl) cyclohexane (5) was found to show a high affinity (IC50 = 16 nM) for the phencyclidine (PCP) binding sites, very close to that of TCP, and to be 38-fold more potent in binding than its trans isomer.
  • (19) In animals sedated with phencyclidine or ketamine the only significant difference detected was in the mean cell volume.
  • (20) [3H]N-1-(2-Thienyl)cyclohexyl-3,4-piperidine binding to the phencyclidine site associated with the N-methyl-D-aspartate receptor was reduced by 60-80% in all brain regions examined (P less than 0.001).