(1) In addition to the phase diagrams reported here for these two binary mixtures, a brief theoretical discussion is given of other possible phase diagrams that may be appropriate to other lipid mixtures with particular consideration given to the problem of crystalline phases of different structures and the possible occurrence of second-order phase transitions in these mixtures.
(2) In 0.17 M Na+(aq), tRNA(Phe) exists in its native conformation and the number of strong binding sites (Ka greater than or equal to 10(4)) was estimated to be 3-4 by titration experiments, in agreement with X-ray structural data for crystalline tRNA(Phe) (Jack et al., 1977).
(3) Electron microscopy revealed the presence of a hitherto unreported peculiar "pilovacuolar" inclusion in numerous mitochondria, composed of an electron dense pile or rod within a vacuole, while globular or crystalline inclusions were absent.
(4) The advantages of the incision through the pars plana ciliaris are (1) easier approach to the vitreous cavity, (2) preservation of the crystalline lens and an intact iris, and (3) circumvention of the corneal and chamber angle complications sometimes associated with the transcorneal approach.
(5) These two crystallins were compared with respect to their native molecular masses, subunit structures, peptide mapping and amino acid compositions in order to establish the identity of each crystallin.
(6) Freeze-dried mannitol preparations were shown to be of a crystalline nature.
(7) Antigenic properties of crystalline pepsin, trypsin and chymotrypsin were studied in 9 rabbits immunised with these enzymes.
(8) X-ray diffraction spectrum of 1:8 coprecipitate (COPPT) showed no crystalline structure of AD.
(9) However, significant differences in the formation and melting of the highly crystalline phase were evident between the two polar headgroup stereoisomers.
(10) Degradation studies of the crystalline antibiotic, m.p.
(11) Crystalline derivatives of the amino sugar i. e. methyleremosaminide and methyl-N,O-acetyleremosaminide (alpha- and beta-anomers) were prepared.
(12) A systematic structural comparison of several carp gamma-crystallins with high methionine contents was made by the secondary-structure prediction together with computer model-building based on the established X-ray structure of calf gamma-II crystallin.
(13) The lens cell-free system synthesizes in addition to the crystallins, polypeptides which co-electrophorese with lens plasma membrane protein components.
(14) Arrhenius plots of the leakage rates showed breaks in the 20-25 degrees C temperature range, which correspond to the gel-liquid crystalline phase transition of the target liposomes.
(15) These results suggest that ATP modulates the functional behavior of alpha-crystallin.
(16) Because anesthetics transform the solid-gel membrane into a liquid-crystalline state, and because phospholipid membranes display an anomaly in permeability at the phase transition, dimyristoylphosphatidylcholine vesicles were studied at temperatures above the main phase transition to avoid this anomaly.
(17) By monitoring the synthesis of specific lens crystallin proteins, and the morphological and cellular changes associated with this differentiated system, we have demonstrated a close correlation between statin expression and cell commitment to the G0 nonreplicative cell cycle state.
(18) Developmental regulation of crystallin protein synthesis was observed in rat lenses between embryonic day 19 and postnatal day 21.
(19) Bovine lens calf gamma-II crystallin contains five histidine residues at sequence positions 14, 53, 84, 117, and 122.
(20) A second crystalline material was observed within cells in the 15,000 X g pellet from spinal fluid.
Hypoxanthin
Definition:
(n.) A crystalline, nitrogenous substance, closely related to xanthin and uric acid, widely distributed through the animal body, but especially in muscle tissue; -- called also sarcin, sarkin.
Example Sentences:
(1) The hprt T-cell cloning assay allows the detection of mutations occurring in vivo in the hypoxanthine-guanine phosphoribosyltransferase (hprt) gene of T-lymphocytes.
(2) The incorporation of inosine or hypoxanthine into the IMP and ITP has been proved.
(3) This method has been used to identify cells with biochemical lesions in the oxidation of propionate, galactose, hypoxanthine and pyruvate; it has allowed us to identify a new variant of methylmalonicaciduria; we believe it can be extended to include other metabolites and pathways.
(4) Here we report that phenol hydroxylation to hydroquinone is also catalyzed by human myeloperoxidase in the presence of a superoxide anion radical generating system, hypoxanthine and xanthine oxidase.
(5) Regulation of the uric acid-xanthine transport system and the hypoxanthine-adenine-guanine transport system was studied.
(6) The oxidation of vitamin E-deficient rat red blood cells (RBCs) induced by the hypoxanthine-xanthine oxidase (HX-XOD) system has been performed in an aqueous suspension.
(7) Only the content of uricogenic bases (adenine and hypoxanthine) varied among the test meals.
(8) We applied a sensitive, precise liquid-chromatographic method of analysis for inosine, hypoxanthine, and xanthine to the study of fructose metabolism in humans and in rats.
(9) The paired cervical and rectal isolates from one patient with uncomplicated gonorrhea differed only with respect to a requirement for hypoxanthine.
(10) Two apparent types of alterations of this enzyme were distinguished: (1) increased specific activity with a normal half life as in megaloblastic anemia, and (2) a prolonged half life with or without an elevation of specific activity as in the deficiency of hypoxanthine-guanine phosphoribosyltransferase.
(11) Inosine and hypoxanthine release were attenuated at the higher dose of deoxycoformycin.
(12) Recovered hybrid cells produced the chick hypoxanthine phosphoribosyltransferase exclusively, as demonstrated by electrophoretic mobility and immunoprecipitation tests, even though no chick chromosomes or chick cell-surface antigens could be identified in the hybrids.
(13) In synchronous cells, uracil DNA glycosylase and hypoxanthine DNA glycosylase were induced with an extent of induction (5-6-fold) comparable to that observed for normal human cells.
(14) Our aim was to evaluate the sensitivity of human fibroblasts, in comparison with umbilical vein endothelial cells, to two common reactive oxygen metabolites, to superoxide produced by hypoxanthine and xanthine oxidase, and to reagent hydrogen peroxide.
(15) Guanosine greater than inosine = hypoxanthine greater than adenosine were taken up with decreasing initial velocities, respectively; adenine was not transported.
(16) Etheno-NADP+, 3-acetylpyridine-adenine dinucleotide phosphate, and nicotinamide-hypoxanthine dinucleotide phosphate act as alternative coenzymes for the enzyme.
(17) A dramatic increase in the concentrations of adenosine, inosine and hypoxanthine was detected by microdialysis in the dorsal part of hippocampus and in the striatum immediately after 5 min bilateral occlusion of the carotid arteries.
(18) If guanine were to be substituted for hypoxanthine in an isogeometrical molecular structure, additional hydrogen bonds could be made between every N-2 and N-7.
(19) HPLC tracing of radiolabelled purines or purine nucleosides revealed that adenine, adenosine and hypoxanthine are incorporated into adenine nucleotides and IMP through a similar channel while guanine and guanosine are salvaged into guanine nucleotides via another route.
(20) Among the four purine bases, adenine and hypoxanthine have been reported to be more uricogenic than guanine and xanthine.