(a.) Burdensome or hindering, as a weight or drag; embarrassing; vexatious; cumbrous.
(a.) Not easily managed; as, a cumbersome contrivance or machine.
Example Sentences:
(1) Since this derived formula is very cumbersome to manipulate, tables have been prepared with computer assistance to read the estimated fetal weight directly.
(2) Determination of right ventricular ejection fraction and volumes from radionuclide studies is cumbersome and is subject to considerable methodologic error.
(3) Downing street – aware of the anguish of the families of these unconfirmed Britons – has privately expressed frustration at the cumbersome process of identification of the bodies following the killings last Friday.
(4) Methodological improvements of the stool smear assay may provide a substantially simplified method for the otherwise cumbersome identification of ETEC.
(5) The apparatus is drawn so that plastic sheets serve as substitutes for the elaborate, but cumbersome and unnecessary, locking systems mounted on all the commercial blotters.
(6) However, using standard methods, processing large numbers of samples for immunofluorescence is cumbersome and difficult.
(7) The conventional Marbrook culture system has several disadvantages; the preparation and assembly of the chambers is time consuming, the size of the culture vessels limits the number of replicates that may be set up, and placing the cells in the inner chamber is a cumbersome and slow process.
(8) However, advances in robotic sample preparation may allow the more cumbersome solid-phase isolation or extraction techniques to be used to improved sample throughput and specificity.
(9) The popular systems of classifying DRUJ disorders are based on etiology and treatment, but this approach has inspired schemes that are cumbersome, redundant, and incomplete.
(10) The EU must be able to act with the speed and flexibility of a network, not the cumbersome rigidity of a bloc.
(11) In the meantime, it is possible to evidence some features, sometimes shared with other species if taken separately, which in the whole characterize the epididymis in Equidae: the presence in principal cells of intranuclear inclusions and peculiar small granules in the basal cytoplasmic edge; the organization of groups of cells, likely to be principal ones, in such a way as to constitute intraepithelial crypts; a cumbersome presence of lipofuscinic matter all along the epithelium.
(12) HLA-DP typing using the Primed Lymphocyte Test (PLT) is a long and cumbersome technique requiring DP sensitized clones and bulk reagents.
(13) The main objections of seeking consent are as follows: it would be too cumbersome to obtain consent; if any patients witheld consent, prevalence studies would be less accurate; testing blood samples anonymously and without consent is an acceptable hospital practice; consent for such tests is not legally necessary; consent may be implied from the consent given to have blood taken; the consent requirement may be ignored in minor procedures; and there is no need for consent because testing could not harm anyone.
(14) A method is described in which a simple disposable plastic umbilical cord clamp replaces the traditional cumbersome instrument or expensive staples in the operation of end colostomy.
(15) Fenech said the multilayered, cumbersome intelligence apparatus was like an army of soldiers wearing lead boots.
(16) The usefulness of this parameter is reduced because of the cumbersome calculations required to determine the time within which an arterial pulse wave conducted via the arteriovenous anomaly reaches the jugular vein.
(17) Such systems are unable to reach a correct diagnosis quickly and often subject the user to a cumbersome dialogue.
(18) The overwhelming priority is to improve our financial and operating performance, improve our speed and response to events and improve internal controls.” East did not go into details about potential job cuts, business disposals, or exiting certain countries, but he said large layers of cumbersome bureaucracy needed to be stripped away so the company could function properly and respond to market changes.
(19) The patient is placed directly on this box, which makes the methods less cumbersome and more suitable for routine use.
(20) The 2-hr continuous measurement is, however, too long for a clinical examination and the 24-hr repeat measurement cumbersome.
Handle
Definition:
(v. t.) To touch; to feel with the hand; to use or hold with the hand.
(v. t.) To manage in using, as a spade or a musket; to wield; often, to manage skillfully.
(v. t.) To accustom to the hand; to work upon, or take care of, with the hands.
(v. t.) To receive and transfer; to have pass through one's hands; hence, to buy and sell; as, a merchant handles a variety of goods, or a large stock.
(v. t.) To deal with; to make a business of.
(v. t.) To treat; to use, well or ill.
(v. t.) To manage; to control; to practice skill upon.
(v. t.) To use or manage in writing or speaking; to treat, as a theme, an argument, or an objection.
(v. i.) To use the hands.
(n.) That part of vessels, instruments, etc., which is held in the hand when used or moved, as the haft of a sword, the knob of a door, the bail of a kettle, etc.
(n.) That of which use is made; the instrument for effecting a purpose; a tool.
Example Sentences:
(1) The high amino acid levels in the cells suggest that these cells act as inter-organ transporters and reservoirs of amino acids, they have a different role in their handling and metabolism from those of mammals.
(2) The most successful dyes were phenocyanin TC, gallein, fluorone black, alizarin cyanin BB and alizarin blue S. Celestin blue B with an iron mordant is quite successful if properly handled to prevent gelling of solutions.
(3) "The Samaras government has proved to be dangerous; it cannot continue handling the country's fate."
(4) Control of cell calcium handling and transport may be abnormal in hypertension.
(5) Equal numbers of handled and unhandled puparia were planted out at different densities (1, 2, 4 or 8 per linear metre) in fifty-one natural puparial sites in four major vegetation types.
(6) Arrogant, narcissistic, egotistical, brilliant – all of that I can handle in Paul,” Levinson writes.
(7) Isolated renal tubules and renal clearance techniques were used to characterize the renal handling of 2-deoxy-D-galactose (2-d-Gal) by the winter flounder (Pseudopleuronectes americanus).
(8) In this study, we examined renal tubular cell handling of digoxin and ouabain using LLC-PK1 cells, a model of proximal renal tubular cells.
(9) Just before Christmas the independent Kerslake report severely criticised Birmingham city council for its dysfunctional politics and, in particular, its handling of the so-called Trojan Horse affair, in which school governors were said to have set out to bring about an Islamic agenda into the curriculum contents and the day-to-day running of some schools.
(10) The effects of insulin on the renal handling of sodium, potassium, calcium, and phosphate were studied in man while maintaining the blood glucose concentration at the fasting level by negative feedback servocontrol of a variable glucose infusion.
(11) The Nd-Yag-Laser seems to be a useful device in transsphenoidal surgery due to its potent coagulation effect and comfortable handling.
(12) Techniques are described for the special handling of these cells as well as suitable assay procedures.
(13) The decision of the editors to solicit a review for the Medical Progress series of this journal devoted to current concepts of the renal handling of salt and water is sound in that this important topic in kidney physiology has recently been the object of a number of new, exciting and, in some instances, quite unexpected insights into the mechanisms governing sodium excretion.
(14) Possible reasons for the previous discrepancies between direct and isotopic methods are discussed, as are the effects of protein binding, sample handling, and storage conditions on oxalate values in plasma.
(15) In addition to working with hist colleagues on general review and health-policy matters, he also handled issues related to the special needs of children and helped to get third-party benefit packages altered to better suit the treatment needs of children.
(16) Furthermore, this system can be satisfactory handled by technical personnel after short periods of training.
(17) The major difficulty encountered with the current technique is the danger of neurologic injury during the passage and handling of conventional wires, especially in extensive procedures.
(18) Both techniques are used by industry and regulatory agencies to monitor levels of fungal contamination at various stages of food handling, storing, processing and marketing.
(19) The particular advantage of the method described here is the ease with which the supernatants can be collected and transferred to counting vials with minimal handling of radioactive samples.
(20) The greatest care should be exercised by industry in handling tremolite or materials contaminated with it.