(a.) Burdensome or hindering, as a weight or drag; embarrassing; vexatious; cumbrous.
(a.) Not easily managed; as, a cumbersome contrivance or machine.
Example Sentences:
(1) Since this derived formula is very cumbersome to manipulate, tables have been prepared with computer assistance to read the estimated fetal weight directly.
(2) Determination of right ventricular ejection fraction and volumes from radionuclide studies is cumbersome and is subject to considerable methodologic error.
(3) Downing street – aware of the anguish of the families of these unconfirmed Britons – has privately expressed frustration at the cumbersome process of identification of the bodies following the killings last Friday.
(4) Methodological improvements of the stool smear assay may provide a substantially simplified method for the otherwise cumbersome identification of ETEC.
(5) The apparatus is drawn so that plastic sheets serve as substitutes for the elaborate, but cumbersome and unnecessary, locking systems mounted on all the commercial blotters.
(6) However, using standard methods, processing large numbers of samples for immunofluorescence is cumbersome and difficult.
(7) The conventional Marbrook culture system has several disadvantages; the preparation and assembly of the chambers is time consuming, the size of the culture vessels limits the number of replicates that may be set up, and placing the cells in the inner chamber is a cumbersome and slow process.
(8) However, advances in robotic sample preparation may allow the more cumbersome solid-phase isolation or extraction techniques to be used to improved sample throughput and specificity.
(9) The popular systems of classifying DRUJ disorders are based on etiology and treatment, but this approach has inspired schemes that are cumbersome, redundant, and incomplete.
(10) The EU must be able to act with the speed and flexibility of a network, not the cumbersome rigidity of a bloc.
(11) In the meantime, it is possible to evidence some features, sometimes shared with other species if taken separately, which in the whole characterize the epididymis in Equidae: the presence in principal cells of intranuclear inclusions and peculiar small granules in the basal cytoplasmic edge; the organization of groups of cells, likely to be principal ones, in such a way as to constitute intraepithelial crypts; a cumbersome presence of lipofuscinic matter all along the epithelium.
(12) HLA-DP typing using the Primed Lymphocyte Test (PLT) is a long and cumbersome technique requiring DP sensitized clones and bulk reagents.
(13) The main objections of seeking consent are as follows: it would be too cumbersome to obtain consent; if any patients witheld consent, prevalence studies would be less accurate; testing blood samples anonymously and without consent is an acceptable hospital practice; consent for such tests is not legally necessary; consent may be implied from the consent given to have blood taken; the consent requirement may be ignored in minor procedures; and there is no need for consent because testing could not harm anyone.
(14) A method is described in which a simple disposable plastic umbilical cord clamp replaces the traditional cumbersome instrument or expensive staples in the operation of end colostomy.
(15) Fenech said the multilayered, cumbersome intelligence apparatus was like an army of soldiers wearing lead boots.
(16) The usefulness of this parameter is reduced because of the cumbersome calculations required to determine the time within which an arterial pulse wave conducted via the arteriovenous anomaly reaches the jugular vein.
(17) Such systems are unable to reach a correct diagnosis quickly and often subject the user to a cumbersome dialogue.
(18) The overwhelming priority is to improve our financial and operating performance, improve our speed and response to events and improve internal controls.” East did not go into details about potential job cuts, business disposals, or exiting certain countries, but he said large layers of cumbersome bureaucracy needed to be stripped away so the company could function properly and respond to market changes.
(19) The patient is placed directly on this box, which makes the methods less cumbersome and more suitable for routine use.
(20) The 2-hr continuous measurement is, however, too long for a clinical examination and the 24-hr repeat measurement cumbersome.
Weighty
Definition:
(superl.) Having weight; heavy; ponderous; as, a weighty body.
(superl.) Adapted to turn the balance in the mind, or to convince; important; forcible; serious; momentous.
(superl.) Rigorous; severe; afflictive.
Example Sentences:
(1) It is appropriate that AIDS be responded to as a crisis, but we also have a weighty, preexisting set of long-standing and equally lethal health and social ills.
(2) Weighty stuff, but critics hailed the show as the neurotic standup’s best in years.
(3) They imply that it is a matter of weighty regret that things have now reached a pass where their only conscionable option is to declare "thus far and no further".
(4) 4S, 5S, AND 18S + 28S RNA from the newt Taricha granulosa granulosa were iodinated in vitro with carrier-free 125I and hybridized to the denatured chromosomes of Taricha granulosa and Batrachoseps weighti.
(5) We'll be here until then and beyond, sharing every rumour nugget, insightful news line and weighty analysis we can muster.
(6) Little ones might freak out a bit at the wax characters and the gloomy dark but this is a fun way to bring a fairly weighty school text to life.
(7) In contrast, D changed from left weightiness to symmetry, coinciding with improvement but not with deterioration, With reference to the latter findings we discuss the possibility of a particular mode of cerebral lateralization predisposing to endogenous depression.
(8) The DPA is a weighty US drug policy reform NGO that can boast tycoons such as George Soros and Richard Branson and celebrities including Sting on its board of directors.
(9) Then there were the imported dramas broadcast because they were weighty, such as 1984's Heimat , an enthralling dramatisation of ordinary lives in 20th-century Germany.
(10) At the time of his resignation he had far more weighty matters filling his in-tray than the NRB case, not least a probe into alleged corruption among some of Boris Yeltsin's close relatives.
(11) Brennan bridles at that, saying it would be "a very weighty decision in terms of declassifying that report."
(12) In the Nederlandsch Tijdschrift voor Geneeskunde the last-mentioned aspect appears to have been very weighty, especially in the beginning.
(13) Weighty, expensive impact reports sit hidden deep within websites (or worse, annual reports), while the public remains oblivious to what happens to donations.
(14) They're running almost entirely on biscuits and cans of Red Bull, kept awake by a mix of jokes, weighty debate, and general good humour.
(15) It's an extra nerdy and intelligent version too, with tactical jedi Jonathan Wilson and his young apprentic Zonal Marking's Michael Cox there to provide the yuks and giggles as myself and James Richardson analyse the weighty football issues of the day to within an inch of their lives.
(16) The world will long remember their son Edward as the heir to a weighty legacy; a champion for those who had none; the soul of the Democratic party; and the lion of the US Senate – a man whose name graces nearly one thousand laws, and who penned more than 300 himself.
(17) It was the world of John Smith, razor-sharp debating, forensic examination of weighty issues and Gaitskellite intrigues.
(18) A comparison between the activity of the two hands yielded a pronounced left-weightiness of object-focused, continuous body-focused and discrete body-focused movements in contrast to findings on normal persons.
(19) The chancellor demanded that officials develop weighty evidence about whether or not the new 50p rate was working.
(20) The science report is the first of three major IPCC reports this year; similarly weighty analysis of the impact and possible solutions will follow in April and May respectively.