(n.) A colorless oily hydrocarbon, C6H5.C3H7, obtained by the distillation of cuminic acid; -- called also cumol.
Example Sentences:
(1) Depending on the ligand, the inhibition profiles of these two iso-enzymes when measured with either the peroxidase substrate, cumene hydroperoxide or the standard GSH S-transferase substrate 1-chloro-2,4-dinitrobenzene were found to be either very similar (sulphobromophthalein) or markedly different (rose Bengal and acrolein).
(2) After exposure to cumene hydroperoxide, formation of high molecular weight protein, presumably through cross-linking of lower molecular weight protein, was stimulated in splenocytes as well as in erythrocyte ghosts.
(3) Mercaptosuccinate (10 microM) inhibits the enzyme competitively (Ki = 7 microM) when cumene hydroperoxide is substrate, and uncompetitively (Ki = 10 microM) when H2O2 is substrate.
(4) Hydrogen peroxide, cumene hydroperoxide, and linoleic acid hydroperoxide were effective as substrates.
(5) We have demonstrated that the nitroxyl free radical form of the carcinogen N-hydroxy-2-acetylaminofluorene (OH-AAF) is an obligatory intermediate in the cumene hydroperoxide-hematin-induced oxidative activation of this carcinogen into 2-nitrosofluorene and N-acetoxy-2-acetylaminofluorene.
(6) Cumene hydroperoxide (230 microM)-induced fall of the membrane potential takes place only in Ca2(+)-loaded mitochondria.
(7) The chemicals studied were: bleomycin, t-butyl hydroperoxide, chromium trioxide, cumene hydroperoxide, formaldehyde, glyoxal, glutaraldehyde, hydrogen peroxide, paraquat, and phenylhydrazine.
(8) In contrast, the liver microsomes from corn oil- or phenobarbital-pretreated rats catalyzed the NADPH- or cumene hydroperoxide-sustained 4-hydroxylation of biphenyl, but the rates of 2-hydroxylation or ethoxyresorufin deethylation were negligible.
(9) The parent compound, alpha-(phenylselenenyl)acetophenone (PSAP), increased the rate of reaction of glutathione with H2O2, tert-butylhydroperoxide, cumene hydroperoxide, linoleic acid hydroperoxide and dilinoleyl lecithin hydroperoxide by 7.0, 25.1, 34.1, 19.1 and 8.4-fold, respectively, as assessed by the oxidized glutathione (GSSG) reductase enzyme assay.
(10) NaIO4 was by far the most effective hydroxylating agent followed by cumene hydroperoxide, NADPH, NaClO2, pregnenolone 17alpha-hydroperoxide, tert-butyl hydroperoxide, and linoleic acid hydroperoxide.
(11) Trolox C and chlorpromazine almost completely prevented the cumene hydroperoxide induced alpha-HBDH release.
(12) Liver showed higher GSH-peroxidase activity with cumene-OOH than with H2O2 as substrate, whereas lung, skeletal muscle and skin presented similar GSH-peroxidase activities with both substrates.
(13) Its activity was tested with the following potential substrates in addition to CDNB: 1,2-dichloro-4-nitrobenzene, p-nitrobenzyl chloride, trans-4-phenylbut-3-en-2-one, 1,2-epoxy-3-(p-nitrophenoxy)propane, ethacrynic acid, menaphthyl sulphate, cumene hydroperoxide, linoleic acid hydroperoxide and 4-hydroxynon-2-enal.
(14) To this end, lung membranes (containing both beta 1- and beta 2-adrenoceptors) and intact erythrocytes (containing a homogeneous beta 2-adrenoceptor population) were pretreated with cumene hydroperoxide (lung membranes with 0.1 mM and erythrocytes with 1 mM) and Fe2+ (1 X 10(-5) M) for 60 min which resulted in extensive lipid peroxidation measured as malondialdehyde formation.
(15) In the presence of glycylglycylhistidine (GlyGlyHis), however, Ni2+ generated cumene peroxyl (ROO.)
(16) Reaction of DNA with OPP or a hydroxylated metabolite of OPP, phenylhydroquinone, in the presence of microsomes and NADPH or cumene hydroperoxide showed four major adducts.
(17) This phenomenon was also observed when the cumene hydroperoxide sensitivity of P-450 IIB1 and IA1 was studied in an isosafrole pretreated rat liver microsomal system.
(18) The effect of cumene hydroperoxide (CHP) in microsomal metabolism of benzo [a]pyrene (BP) was studied using liver microsomes from mature male Wistar rats induced with phenobarbital (PB), 3-methylcholanthrene (MC), Aroclor 1254 or olive oil (uninduced).
(19) Cumene hydroperoxide (40 microM) induced a three-fold increase in HMS in both HUVEC and HUAEC, while fibroblasts exhibited an increase of 83%.
(20) Addition of 1 microM alpha-tocopherol also increased the amount of cumene hydroperoxide tolerated to 50 microM.
Iupac
Definition:
Example Sentences:
(1) The concentrations of the isomers 2,4,4'5-tetraCB (IUPAC 74), 2,2',4,4',5,5'-hexaCB (IUPAC 153), 2,2',3,4,4'5'-hexaCB (IUPAC 138), 2,3,3',4,4',5-hexaCB (IUPAC 156), 2,2',3,4,4',5',6-heptaCB (IUPAC 183), and 2,2',3,3',4,4',5-heptaCB (IUPAC 171) showed close correlation, the coefficients varied from 0.42 to 0.98.
(2) Consequently, IUPAC suggests this procedure as a recommended method.
(3) In Pseudomonas aeruginosa c-551 the 13-propionate (IUB-IUPAC porphyrin nomenclature) has been assigned a pKa of 3.1, and the 17-propionate a pKa of 7.2.
(4) Formaldehyde (IUPAC name, methanal) is one of the simplest, most ubiquitous molecules in our environment and troposphere.
(5) One pathway permits a fast descent to the atomic structure in terms of correct IUPAC carbon atom occurrence numbers.
(6) The congeners were 28, 52, 101, 118, 153, 138, 180, 170, and 209 (IUPAC numbering system, Ballschmiter and Zell 1980).
(7) About 70% of the PCB residues in the sample analysed consisted of only three congeners: 2,2',4,4',5,5' (IUPAC No.
(8) Concentrations of ten toxic coplanar PCBs (IUPAC Nos.
(9) A chemical substance database, containing chemical structures generated automatically from their IUPAC systematic names, is described.
(10) In the present study, a definition of the reference values of blood cadmium (Cd-B) and urinary cadmium (Cd-U) was attempted, adopting the same methodology as that used for Hg-B by ICOH and IUPAC.
(11) the tautomer having a proton bound to the nitrogen atom at position 1 of the ring, where the ring is numbered according to IUPAC-IUB convention) can be calculated from the following equation: XII congruent to 1.705--0.164 3J(C5,H2)obs.
(12) The IUPAC torsional parameters for 100 conformations are illustrated using a wheal and a dial systems.
(13) The investigated yeasts grown on carbohydrates keep the limit of 5 ppb benzo(a)-pyrene recommended by the IUPAC.
(14) One duplicated hexokinase (4a and 4b according to the IUPAC-nomenclature) was detected in rabbit erythrocytes as also described for human erythrocytes.
(15) The IUPAC name is: N-[-1'-(2''-amino-4''-hydroxy-7''-proton-6''-pteridinyl)ethyl]-4- [2',3',4',5'-tetrahydroxypent-1'-yl(5'----1'')O-alpha- ribofuranosyl-5''-phosphoric acid]aniline, in which the phosphate group is esterified with alpha-hydroxyglutarylglutamylaspartic acid.
(16) An international collaborative study of IUPAC methods II.D.19 and II.D.25 for preparation and GLC analysis of fatty acid methyl esters was begun in 1976.
(17) The use of a biodegradable polymer for antigen delivery based on poly(CTTH-iminocarbonate) (IUPAC nomenclature: poly[oxyimidocarbonyloxy-p-phenylene [2-(hexyloxycarbonyl)ethylene]imino[2-[1-(benzyloxy)formamido]- 1-oxotrimethylene]-p-phenylene]) was investigated.
(18) Group 1A contains the three most potent (pure 3-MC-type inducer) congeners, IUPAC numbers 77, 126, and 169.
(19) The results of a collaborative study, stimulated by IUPAC, are reported: Coefficients of variation for the various azaarenes were 4.0-13.6% for the check analysis and 10.4-25.4% for a spiked ham sample.
(20) The conformational parameters are in accordance with the IUPAC-IUB Joint Commission on Biochemical Nomenclature [Pure Appl.