What's the difference between curarize and poison?
Curarize
Definition:
(v. t.) To poison with curare.
Example Sentences:
(1) As an inspiratory monitor in the curarized patient, the sensor responds quantitatively to persisting spontaneous tidal volumes of 1 ml.
(2) Protamine sulphate in vitro antagonized anticoagulant properties but did not protect mice from toxic envenomation; because venom was also neurotoxic and showed a curare like effect at the neuromuscular junction.
(3) Specificity of the assay for nicotinic receptors was confirmed by the relative abilities of the following compounds to prevent 125I-BGT binding: curare greater than or equal to nicotine greater than hexamethonium greater than atropine.
(4) Ca2+-ATPase of rats and rabbits skeletal muscle sarcolemma was studied as affected by relaxants: tubocurarine, myorelaxin and dioxonium, and by anesthetic fluothane in experiments in vitro and in vivo with lung artificial ventilation during curarization.
(5) In decorticate and in spinal curarized rabbit preparations, respiratory and locomotor rhythms can be closely related (1:1 coupling between successive periods), demonstrating central relationships between the two types of pattern generators.
(6) When the interaction of these two agents is being evaluated it is important to consider the doses of the agents, the stage of curarization where the interaction took place and the method of assessing the neuromuscular blockade.
(7) The effect of curare on the amount of transmitter released by a nerve stimulus was studied in frog and rat nerve-muscle preparations using electrophysiological techniques.2.
(8) The root bark of S. paludosum which showed curare like activity yielded tomatidenol and another yet unidentified alkaloid responsible for the biological activity.
(9) The relationship between the therapeutic doses and the curarizing doses had a greater margin of security with the three antibiotics than with streptomycin.
(10) The agents could be divided into 4 classes: (1) agents having no effect upon transmission at this cholinergic junction; (2) agents of a class typified by curare, which depressed all EPSPs of a train to the same extent, and which are believed to be acting in this system solely as competitive postsynaptic blockers; (3) agents typified by acetylcholine and carbachol (ACh class), which selectively depressed earlier EPSPs of a train more than later EPSPs and which appear to act by reducing the fractional release of transmitter; (4) agents typified by trimethidinium (trimethidinium class), which selectively depress later EPSPs of a train more than earlier EPSPs and which appear to act by reducing the rate of transmitter supply into the readily releasable pool.
(11) Denervation produced by mechanically removing the neurite from the muscle cell also produced similar hyperpolarization, and curarization after denervation was without significant hyperpolarizing effect.
(12) The discovery of the safety margin of neuromuscular transmission has brought forth the requirement for an improvement in the clinical examination of curarization, since the safety margin, i.e.
(13) This non-quantal ACh release is revealed by the hyperpolarization of the muscle membrane following extracellular application of curare or alpha-bungarotoxin, as well as by denervation of the muscle cell.
(14) The 125I-alpha-Bgtx binding is inhibited by curare, decamethonium, hexamethonium but not by carbamylcholine and Naja naja siamensis alpha-toxin and P15 toxin.
(15) Furthermore, because the doses of curare used inhibit motor activity by more than 80%, the fetal transition can occur in the absence of normal levels of motor activity.
(16) The binding was prevented by pretreatment of sperms and activated eggs with 10 nM native alpha-BuTx and 10 microM curare.
(17) According to our experience, the response to carotid body stimulation with cyanide, in normal breathing dogs, consists in hyperpnoea, bradycardia with arterial blood pressure fall (by means of longer diastolic periods), followed by a marked rise in arterial blood pressure and heart rate, after curarization.
(18) The influence of stimulation of stria terminalis and midbrain central gray substance on the neuronal activity of the lateral hypothalamus was studied in acute experiments on curarized rats.
(19) Motor axons can form sprouts from their terminal arborizations in response to partial denervation, and when exposed to pharmacological blocking agents like TTX, botulinum toxins alpha-bungarotoxin, or curare.
(20) Magnetically carried microspheres were used to investigate whether the curare-like drugs can be selectively transported to the muscles of one of the limbs of the cat.
Poison
Definition:
(n.) Any agent which, when introduced into the animal organism, is capable of producing a morbid, noxious, or deadly effect upon it; as, morphine is a deadly poison; the poison of pestilential diseases.
(n.) That which taints or destroys moral purity or health; as, the poison of evil example; the poison of sin.
(n.) To put poison upon or into; to infect with poison; as, to poison an arrow; to poison food or drink.
(n.) To injure or kill by poison; to administer poison to.
(n.) To taint; to corrupt; to vitiate; as, vice poisons happiness; slander poisoned his mind.
(v. i.) To act as, or convey, a poison.
Example Sentences:
(1) Resistance to antibiotics have been detected in food poisoning bacteria, namely Salmonella typhimurium, Staphylococcus aureus and Clostridium perfringens.
(2) It can induce acute cholinesterase poisoning, which is rapidly reversible on discontinuation of exposure.
(3) There is a disparity between the number of reported cases of poisoning and the number of chemical analyses performed for the identification and quantitative determination of a particular poison.
(4) A case is presented of deliberate chewing of the flowers of henbane (Hyoscyamus niger) in the hope of producing euphoria, and an account is given of the poisoning so produced.
(5) "Our black, Muslim and Jewish citizens will sleep much less easily now the BBC has legitimised the BNP by treating its racist poison as the views of just another mainstream political party when it is so uniquely evil and dangerous."
(6) Extrapyramidal syndromes after ischemic anoxia are rare, when compared to their relative frequency after carbon monoxide poisoning.
(7) Concern about the safety of the patient and dental personnel does exist, however, due to the possibilities of mercury poisoning.
(8) Excess levels of selenium (2.5 and 5 ppm) in the vitamin E-deficient diet had little or no effect on spleen size or hematocrit of rats not receiving lead, but partially prevented the splenomegaly and anemia of red cells from either non-poisoned or lead-oisoned vitamin E-deficient rats, but not as effectively as vitamin E. These results show that vitamin E status of rats is more important that selenium status in determining response to toxic levels of lead.
(9) Toxicity has been reported in the fetus of a woman ingesting a huge overdose of digitoxin; the same result would be anticipated with digoxin poisoning.
(10) Three esterase inhibitors, phenylmethylsulfonyl fluoride, bis-(p-nitrophenyl)-phosphate, and diisopropylfluorophosphate, had no effect on the antidote effectiveness of N-acetylcysteine, although each provided partial protection against acetaminophen poisoning.
(11) The deaths were due to: hanging (41 cases), poisoning (17 cases), leaping from a height (7 cases), and others (11 cases including one case of self shooting).
(12) In vivo the administration of captopril prevented the toxic effects of mercury poisoning on membrane permeability, oxidative phosphorylation and Ca++ homeostasis.
(13) Large doses of dsFab are efficacious in the treatment of dysrhythmias in this canine model of N oleander cardiac glycoside poisoning.
(14) A recent report indicated that an arrow poison used by the native Indians of Rondonia, Brazil, to kill small animals was associated with profuse bleeding.
(15) When Hayley Cropper swallows poison on Coronation Street on Monday night, taking her own life to escape inoperable pancreatic cancer, with her beloved husband, Roy, in pieces at her bedside, it will be the end of a character who, thanks to Hesmondhalgh's performance, has captivated and challenged British TV viewers for 16 years.
(16) Zelaya's food comes separately and is prepared by his daughter because he fears being poisoned.
(17) Characteristics of the poisoning include a delay between exposure and onset of symptoms; early systemic toxicity with congestive changes in the lungs and oliguric renal failure; prominent cerebellar and Parkinsonian neurologic symptoms as well as seizures and coma in severe cases; and psychiatric disturbances that can last from months to years.
(18) A method of poisoning cats with thallium is described.
(19) They were given individually to guinea pigs prior to poisoning with 2 x LD50 soman to test their efficacy against organophosphorus-induced convulsions, brain damage, and lethality.
(20) This incident prompted the poison center to evaluate our emergency response capabilities.