(v. t.) To separate the parts of with, or as with, a sharp instrument; to make an incision in; to gash; to sever; to divide.
(v. t.) To sever and cause to fall for the purpose of gathering; to hew; to mow or reap.
(v. t.) To sever and remove by cutting; to cut off; to dock; as, to cut the hair; to cut the nails.
(v. t.) To castrate or geld; as, to cut a horse.
(v. t.) To form or shape by cutting; to make by incision, hewing, etc.; to carve; to hew out.
(v. t.) To wound or hurt deeply the sensibilities of; to pierce; to lacerate; as, sarcasm cuts to the quick.
(v. t.) To intersect; to cross; as, one line cuts another at right angles.
(v. t.) To refuse to recognize; to ignore; as, to cut a person in the street; to cut one's acquaintance.
(v. t.) To absent one's self from; as, to cut an appointment, a recitation. etc.
(v. i.) To do the work of an edged tool; to serve in dividing or gashing; as, a knife cuts well.
(v. i.) To admit of incision or severance; to yield to a cutting instrument.
(v. i.) To perform the operation of dividing, severing, incising, intersecting, etc.; to use a cutting instrument.
(v. i.) To make a stroke with a whip.
(v. i.) To interfere, as a horse.
(v. i.) To move or make off quickly.
(v. i.) To divide a pack of cards into two portion to decide the deal or trump, or to change the order of the cards to be dealt.
(n.) An opening made with an edged instrument; a cleft; a gash; a slash; a wound made by cutting; as, a sword cut.
(n.) A stroke or blow or cutting motion with an edged instrument; a stroke or blow with a whip.
(n.) That which wounds the feelings, as a harsh remark or criticism, or a sarcasm; personal discourtesy, as neglecting to recognize an acquaintance when meeting him; a slight.
(n.) A notch, passage, or channel made by cutting or digging; a furrow; a groove; as, a cut for a railroad.
(n.) The surface left by a cut; as, a smooth or clear cut.
(n.) A portion severed or cut off; a division; as, a cut of beef; a cut of timber.
(n.) An engraved block or plate; the impression from such an engraving; as, a book illustrated with fine cuts.
(n.) The act of dividing a pack cards.
(n.) The right to divide; as, whose cut is it?
(n.) Manner in which a thing is cut or formed; shape; style; fashion; as, the cut of a garment.
(n.) A common work horse; a gelding.
(n.) The failure of a college officer or student to be present at any appointed exercise.
(n.) A skein of yarn.
(a.) Gashed or divided, as by a cutting instrument.
(a.) Formed or shaped as by cutting; carved.
(a.) Overcome by liquor; tipsy.
Example Sentences:
(1) A subsample of patients scoring over the recommended threshold (five or above) on the general health questionnaire were interviewed by the psychiatrist to compare the case detection of the general practitioner, an independent psychiatric assessment and the 28-item general health questionnaire at two different cut-off scores.
(2) McDonald said cutting better deals with suppliers and improving efficiency as well as raising some prices had only partly offset the impact of sterling’s fall against the dollar.
(3) The playing fields on which all those players began their journeys have been underfunded for years and are now facing a renewed crisis because of cuts to local authority budgets.
(4) Finally, the automatized measurement system cuts the time spent by a factor of more than five.
(5) We could do with similar action to cut out botnets and spam, but there aren't any big-money lobbyists coming to Mandelson pleading loss of business through those.
(6) It comes as the museum is transforming itself in the wake of major cuts in its government funding and looking more towards private-sector funding, a move that has caused some unease about its future direction.
(7) Chromatolysis and swelling of the cell bodies of cut axons are more prolonged than after optic nerve section and resolve in more central regions of retina first.
(8) Guardian Australia reported last week that morale at the national laboratory had fallen dramatically, with one in three staff “seriously considering” leaving their jobs in the wake of the cuts.
(9) It is proposed that this "zipper-like" mechanism represents the normal cutting process of the septum during cell separation.
(10) Limitations include the facts that the tracer inventory requires a minimal survival period, can only be done postmortem, and has low resolution for cuts of the vagal hepatic branch.
(11) White lesions (NRL) against a gray background on cut section of brain increase in size with increasing time of arrest.
(12) She was clearly elected on a pledge not to cut school funding and that’s exactly what is happening,” Corbyn said.
(13) We are in the middle of the third year of huge cuts in acute hospitals' budgets," said Porter.
(14) This includes cutting corporation tax to 20%, the lowest in the G20, and improving our visa arrangements with a new mobile visa service up and running in Beijing and Shanghai and a new 24-hour visa service on offer from next summer.
(15) Leaders of Tory local government are preparing radical proposals for minimum 10% cuts in public spending in the search for savings.
(16) Size comparison of the newly discovered Msp I fragment with a restriction map of the apolipoprotein A-I gene revealed that most likely the cutting site at the 5'-end of the normally seen 673 bp fragment is lost giving rise to the observed 719 bp Msp I fragment.
(17) The drugs were moderately potent inhibitors of both E. electricus and C. elegans acetylcholinesterase but at concentrations too high to account for their abilities to contract cut worms.
(18) Although various micronutrients (vitamins and trace elements) have also been found to have either a positive or negative association, findings were more clear-cut for the different food items contributing the micronutrients than for the specific micronutrients themselves.
(19) On taking office Lansley admitted this was not a deep enough cut.
(20) "If you are not prepared to learn English, your benefits will be cut," he said.
Scissile
Definition:
(a.) Capable of being cut smoothly; scissible.
Example Sentences:
(1) The minimal length for an effective substrate has been characterised as an octapeptide sequence derived from the amino terminal portion of angiotensinogen (residues 6----13): His-Pro-Phe-His-Leu-Val-Ile-His (Leu-Val is the scissile bond).
(2) For the native zymogen the rate of this conversion had been shown to be identical to the rate of cleavage of the scissile bond of pepsinogen.
(3) Mutations were introduced at amino acids downstream of the F-P scissile bond, at positions P4' and P5' in the C-terminal site (TLNF*PISP), and at position P3' in a consensus N-terminal site (TLNF*PQITL) placed at the protease-beta-gal junction.
(4) In the acid proteases the electrophilic component is the proton shared by Asp-32 and Asp-215; Tyr-75 donates its proton to the amide nitrogen of the scissile bond and an OH- ion from a water molecule bound between the carboxyl group of Asp-32 and the substrate attacks the carbonyl carbon atom.
(5) Replacement of the scissile bond with the phosphinic analogue of Leu10-Val11 (1b) gave the most potent inhibitors, having IC50 = 7.5 x 10(-8) M for H-Pro-His-Pro-Phe-His-(1b)-Ile-His-Lys-OH and IC50 = 1.0 x 10(-7) M for Z-Arg-Arg-Pro-Phe-His-(1b)-Ile-His-NH2.
(6) We show that a DNA fragment containing phosphorothioate linkages at the NaeI scissile bonds (S-activator) is not cleaved by NaeI, even though this S-activator binds to the substrate site.
(7) A set of DNA duplexes with repeated EcoRII, EcoRI and AluI restriction endonuclease recognition sites in which EcoRII scissile phosphodiester bonds were replaced by phosphoramide or uncleavable pyrophosphate bonds have been synthesized.
(8) By contrast, placement of a beta-branched (Val) residue in the P2 position flanking such -Hydrophobic*Hydrophobic- junctions resulted in effective cleavage of the scissile peptide bond.
(9) These diamines were incorporated into renin inhibitors (IC50 = 4-1500 nM) replacing the Leu-Val scissile bond in small peptide analogues of angiotensinogen.
(10) Secondary enzyme-substrate interactions at sites removed from the scissile bond are indicated by the finding that a hydrophobic or bulky residue in the P3' position greatly contributes to substrate binding and catalytic efficiency.
(11) Looking at the amino acid residues on the amino side of the scissile bond we found three times the Tyr-Pro pair at P'1-P'2 positions and that the S'1 subsite can interact with modified amino acids such as phosphoserine.
(12) In an attempt to convert the p17-p24 domain into a p24-p15 domain, residues flanking the scissile bond were exchanged in an expanding iterative fashion.
(13) Its spatial structure and the conformation of its primary binding segment from Cys-3I (P3) to Glu-7I (P3') which contains the reactive scissile bond Arg-5I C-Ile-6I N were also very similar with other squash family proteinase inhibitors.
(14) This interdomain region contains the sequence ...Asn-Tyr-Pro-Thr... which is similar to that surrounding the scissile Tyr-Pro bond in the gag precursor polyprotein, a natural substrate of the HIV-1 protease.
(15) Analogues of the renin octapeptide substrate were synthesized in which replacement of the scissile dipeptide with (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid (statine, Sta) transformed the substrate sequence into potent, transition-state analogue, competitive inhibitors of renin.
(16) Three cyclic compounds were synthesized with ring sizes 10, 12, and 14, based upon a linear hexapeptide inhibitor with a reduced amide replacing the scissile bond at the active site.
(17) Subsites accommodating residues COOH-terminal to the scissile bond were also important in determining the overall substrate specificity of these proteinases.
(18) In contrast with the corresponding lactosides and 1-thiocellobiosides, and in conflict with the expected specificity, aromatic 1-O-beta-cellobiosides are apparently hydrolysed at both scissile bonds, yielding the glucoside as one of the main reaction products.
(19) Important binding interactions are contributed by VIP(22-28), a sequence four residues distant from the scissile bond.
(20) Substitution of the amino acids flanking the scissile bond at three of the processing sites encoded by pol demonstrates distinct sequence requirements for cleavage at these different sites.