(1) The ternary complex consisting of a 65-kDa peptide originating from the proteoglycan core protein and a 43-kDa link protein bound to hyaluronic acid was purified from a clostripain digest of the rat chondrosarcoma aggregating proteoglycan and 14C-carbamylated with potassium [14C]cyanate.
(2) Oxygen consumption in cyanate-treated mice was significantly lower than in controls in room air but not different in hypoxic environments.
(3) The action of melphalan and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) in prolonging the survival time of melanoma-bearing mice was not enhanced by combined treatment with sodium cyanate.
(4) The kinetic 13C isotope effect on the decomposition of carbamoyl phosphate to cyanate and phosphate is 1.058.
(5) The binding of cyanate, galactose and glucose 6-phosphate to lens proteins, and the effect of ibuprofen on this reaction was investigated, as was cyanate-induced opacification in whole rat lenses.
(6) Another interesting property of PtdIns-glycan-specific phospholipases is their inactivation by bicarbonate and cyanate.
(7) The ability to respond to oral cyanate therapy was correlated with the amount of stainable iron in the bone marrow aspirate.
(8) In previous studies, we have found that combined treatment with BCNU and sodium cyanate could have a greater effect on the survival of mice bearing B16 melanoma than treatment with either agent alone.
(9) The inhibition of the binding of [14C]-glucose and [14C]-cyanate to the aspirin pre-treated crystallins suggests that prior acetylation with aspirin prevents the occurrence of the nonenzymatic glycosylation and carbamylation of the lens crystallins in vitro.
(10) The competitive inhibitor boric acid protects mesentericopeptidase against inactivation with potassium cyanate.
(11) Cyanate, which is in equilibrium with urea, combines with the alpha-amino group of the aminoterminal valine of hemoglobin in an irreversible, specific carbamylation reaction.
(12) Chemical modification of 15% of the lysine residues of LDL by carbamylation with cyanate or 20% by acetoacetylation with diketene prevents the LDL from competitively displacing unmodified 125I-LDL from the high affinity receptor sites or from binding directly to the receptor.
(13) The effect of carbamyl phosphate on glutathione concentrations, however, was virtually identical to that of cyanate.
(14) Pretreatment of mice with potassium cyanate for 15 days resulted in a significant increase in hemoglobin-oxygen affinity (decrease in P 50) and a significant protection against hypoxic hypoxia-induced lethality.
(15) Cyanate administered to mice at a dose of 30 mg per kg per day did not delay allograft rejection.
(16) NH2-terminal analysis by both the dansylation and cyanate procedures failed to identify a free NH2 terminus.
(17) Preincubation of lysates with cyanate or fluoride markedly decreased acetaldehyde-mediated transaminase inhibition but not aldolase inhibition.
(18) In an attempt to understand the variability of the hematologic response to oral sodium cyanate, iron metabolism was studied in a group of 39 patients with sickel cell disease.
(19) Two carbamylating agents, carbamyl phosphate and sodium cyanate, are currently being evaluated as therapeutic drugs for the treatment of sickle cell anemia.
(20) Hemoglobin carbamylation with sodium cyanate was used to study myocardial O2 delivery during increased oxyhemoglobin affinity.
Thiocyanate
Definition:
(n.) Same as Sulphocyanate.
Example Sentences:
(1) Neither were any significant differences found in blood carboxyhemoglobin nor serum thiocyanate.
(2) Conversion of the active-site thiol to thiocyanate makes it more difficult to inactivate the enzyme by treatment with Cd2+.
(3) Addition of potassium thiocyanate increased the number of high affinity [3H]AMPA binding sites without a change in affinity.
(4) Dogs fed on both gari diet and the rice + cyanide diet generated significant amounts of thiocyanate when compared with the controls, with the rice + cyanide group having higher plasma thiocyanate than the gari group (P less than 0.01).
(5) Pancreatic RNAs were isolated by the guanidinium thiocyanate method and layered onto CsCl cushion.
(6) The ability to generate the mononuclear cell chemotactic factor in serum that has been treated with potassium thiocyanate suggests that complement is not required.
(7) Thiocyanate and triazinyl chloride derivatives of fluorescent dyes have been employed for the covalent labeling of components of the connective tissue of the rabbit cornea.
(8) The toxic metabolizing degree was investigated by measuring plasma and urine thiocyanate levels.
(9) The availability of recombinant dihydrolipoamide transacetylase and the development of a rapid and reproducible enzyme-linked immunosorbent assay for autoantibodies has allowed us to address the affinity of autoantibodies using thiocyanate inhibition.
(10) The urinary elimination of thiocyanate was investigated in male and female rats following the chronic administration of potassium cyanide.
(11) Laboratory investigation on a sample of this population demonstrated very high levels of serum and urinary thiocyanate, indicating a heavy exposure to cyanide.
(12) Granulocyte motility is, however, stimulated by ascorbic acid, potassium thiocyanate, levamisole, lithium, and metofenazate.
(13) After 16 weeks small amounts of peroxides were present in adipose tissue as determined by the thiocyanate method.
(14) Cation transport acceleration induced by the monovalent anions salicylate, benzoate, thiocyanate and 2,4-dinitrophenol were inhibited by dipyridamole, but not affected by SITS.
(15) The inhibitor decomposed by a mechanism involving H(+) ions and thiocyanate, the kinetics varying according to whether the inhibitor was in its acidic or basic form.
(16) Serum thiocyanate concentrations were measured by the ferric nitrate method.
(17) In a study on lung adenomas induced by the administration of a single intragastric dose of sodium thiocyanate, diethylnitrosamine, or its precursors to 15-day-old C57BLxC3H F1 mice the occurrence of crystalline inclusions in pulmonary parenchyma was noted.
(18) Human milk and saliva from newborn infants were analyzed for their content of lactoperoxidase and thiocyanate.
(19) At the translocation step the inhibition function was the same for the two inhibitors, and though similar at the formation step, they differ in that a Hill coefficient larger than unity is necessary in the thiocyanate inhibition function of the acid formation.
(20) Addition of the thiocyanate to the food may be beneficial through a nutritive effect.