(n.) The substance of the body of a cell, as distinguished from the karyoplasma, or substance of the nucleus.
Example Sentences:
(1) 5-HT thus appears to be the preferred substrate for uptake into platelets and for movement from cytoplasm to vesicles.
(2) The monoclonal antibody (mAb), SY38, binds to a cytoplasmic domain of synaptophysin.
(3) Immunofluorescence analysis of Pr-28 antigen showed that the antigen was localized mainly in perinuclear cytoplasm.
(4) Their contour lengths varied from 0.28 to 51 micron, but unlike in the case of maize, a large difference was not observed in the distribution of molecular classes greater than 1.0 micron between N and S cytoplasms of sugar beet.
(5) Chloroquine induced large cytoplasmic vacuoles, whereas the other drugs (quinacrine, 4,4'-diethylaminoethoxyhexestrol, chlorphentermine, iprindole, 1-chloro-amitriptyline, clomipramine) caused formation of lamellated or crystalloid inclusions as usually seen in drug-induced lipidosis.
(6) Aside from these characteristic findings of HCC, it was important to reveal the following features for the diagnosis of well differentiated type of small HCC: variable thickening or distortion of trabecular structure in association with nuclear crowding, acinar formation, selective cytoplasmic accumulation of Mallory bodies, nuclear abnormalities consisting of thickening of nucleolus, hepatic cords in close contact with bile ducts or blood vessels, and hepatocytes growing in a fibrous environment.
(7) RNA transcribed in vitro from the early region of bacteriophage T3 or T7 was translated by cytoplasmic ribosomes which synthesized protein in cell-free systems prepared from mammalian cells and wheat germ.
(8) The ability of cytoplasmic extracts to induce DNA synthesis in isolated, quiescent nuclei.
(9) P2 is a cytoplasmic protein, while P1 largely fractionates with the membrane.
(10) In contrast, in primordial follicles, FSH was restricted to the germ cell but was present in both the oocyte cytoplasm and germinal vesicle.
(11) Digestion of cytoplasmic components of horny cells was observed by electron microscopy, but both cell membranes and desmosomes remained intact.
(12) The lymphocyte-specific phosphoprotein LSP1 associates with the cytoplasmic face of the plasma membrane and with the cytoskeleton.
(13) We have previously shown that about 90% of total Escherichia coli lac repressor synthesized in mammalian cells is located in the cytoplasm [Hu and Davidson, Cell 48 (1987) 555-566].
(14) Cytoplasmic organelles were displaced and rearranged in the presence of somal neurofibrillary changes.
(15) After Listeria, a bacterium, is phagocytosed by a macrophage, it dissolves the phagosomal membrane and enters the cytoplasm.
(16) Immunocytochemical analysis also suggested that bFGF immunoreactivity was present in the nucleus as well as the cytoplasm of astrocytes and CA2 neurons.
(17) Losses of RNase activities in preneoplastic tissues are followed by changes in the properties of cytoplasmic RNA probably due to alterations in ribosomes in areas of neoplastic transformation.
(18) The role of cytoplasmic microtubules (MTs) in the structural organization of the Golgi complex and the lysosomal system was studied in L929 mouse fibroblasts using a combination of cytochemical and electron microscopic methods.
(19) Increases were found in both nuclei and cytoplasm of trophoblast cells in the labyrinth region.
(20) After 10-20 hr of culture, both membrane and cytoplasmic PKC activity had declined to background levels.
Protoplasm
Definition:
(n.) The viscid and more or less granular material of vegetable and animal cells, possessed of vital properties by which the processes of nutrition, secretion, and growth go forward; the so-called " physical basis of life;" the original cell substance, cytoplasm, cytoblastema, bioplasm sarcode, etc.
Example Sentences:
(1) Fixation with buffered glutaraldehyde resulted in higher counts (P less than 0.01) of proximal protoplasmic droplets (2.47, 1.03, 0.67, and 1.43%, respectively, for glutaraldehyde, Hancock's, Blom's, and formol saline procedures).
(2) Small, diffusely GJP-IR cells were identified ultrastructurally as protoplasmic and fibrous astrocytes.
(3) Protoplasmic cylinders contained within such granules frequently were devoid of cell envelopes.
(4) The infected cells treated by this method showed light green fluorescence of the protoplasm, with a dark nucleus, while the intact cells had tile-red cytoplasm.
(5) That T-tubules isolated by disruption of triad junctions are constrained to have the protoplasmic (P) face uniformly exposed was experimentally confirmed.
(6) The morphological change of cerebral cortex astrocytes from protoplasmic to glial fibrillary acidic protein (GFAP)-containing cells is induced by injury.
(7) Pretreatment of mice by intravenous injection with killed Listeria provided neither delayed-type hypersensitivity to Listeria protoplasm nor protection against Listeria infection.
(8) The greatest motion of protoplasmic droplets was recorded in the caput epididymidis, although the migration of droplets from the proximal section of the connective part of the flagellum towards the distal parts could also be observed as far as in the cauda epididymidis in both animals.
(9) Thus staining techniques that have a propensity for the glial filaments such as antisera to glial fibrillary acidic protein and the gold-chloride method provide only a skeletal outline of the major processes of the protoplasmic astrocyte.
(10) Within this context, we would like to present a case discussion regarding a 27-month-old boy with a hypothalamic-midbrain protoplasmic glioma treated with primary chemotherapy after surgical biopsy and pathologic documentation.
(11) The toxin appears to be protoplasmic and is released into the surrounding environment upon autolysis of the cells.
(12) To improve the definitions, eliminate overlapping diagnostic categories, and sharpen the fuzzy boundaries that contribute substantially to limited reproducibility, we suggest: (1) the categories of astrocytoma nos, fibrillary astrocytoma, and protoplasmic astrocytoma be collapsed into a single category of astrocytoma; (2) the diagnostic category of desmoplastic medulloblastoma be combined with medulloblastoma; and (3) the criteria for anaplasia should be further refined to include quantification of critical histologic features, e.g., agreed upon operational definitions for amount of cell density, number of mitoses and pleomorphism for anaplastic astrocytoma and anaplastic ependymoma.
(13) They mainly concentrate on the membrane protoplasmic surface.
(14) The incompatibility reaction when vegetative or sexual R and V cells fuse is asymmetric: it is induced only in the R protoplasm.
(15) The intramembranous particles in the protoplasmic face of fractured membranes obtained from fresh cells incubated with 1 mM of Ca2+ were more scattered and their density was lower than in control cells.
(16) Morphometric analysis of the outgrowth zone revealed a statistically significant decrease in the incidence of fibroblastic-reactive microglial cells (from 12 to 0%), and a significant increase in the incidence of protoplasmic astrocytic-epithelial cells (from 82 to 96%), for AraC-treated explants compared to controls.
(17) Periplasmic bodies were most prevalent in the regions of the bud scars and were often accommodated within large invaginations in the protoplasmic membrane.
(18) However, electron microscopic immunocytochemical analysis of NG2 immunoreactive cells revealed a cell morphology consistent with that of protoplasmic astrocytes.
(19) (2) It has been shown that in protoplasmic drops the endoplasm-ectoplasm transformation is accompanied by an actin polymerization from the non-filamentous state to F-actin.
(20) These studies are based upon the observation that a number of experimental maneuvers can alter tissue permeability to water, but do not change the number of particle aggregates observed on the protoplasmic face of the granular cell's luminal membrane with freeze-fracture electron microscopy.