(n.) Father; -- a word sometimes used by children.
Example Sentences:
(1) To many he was a rockstar, to me he was simply 'Dad', and I loved him hugely.
(2) The reason I liked them was because they were a band, and my dad had a band.
(3) My dad had just died, and he was born on the very same day, in the very same year.
(4) Prince was named after his father's own stage persona, and when his parents split up he became determined to better his dad on piano.
(5) If he was a cartoon character, he’d be … On looks alone, American Dad’s Stan Smith .
(6) It will make entering the market more difficult still for new buyers, further highlighting the importance of the right timing, advice, support and financial planning; and not just having a mum and dad who bought a house, but a grandparent, too.” Average UK house price reaches £288,000 Read more The average property price in the UK, currently £283,565, is expected to double by 2030, breaking through the £500,000 mark to £557,444.
(7) I saw my dad sitting in the audience, looking at me like, “Yes, he really is crazy.” Having listened to thousands of people, I realised we had a narrow view of what the environment is.
(8) He is Taurus and I'm Pisces; my dad was Pisces and my mum was Taurus.
(9) DADs may reach a magnitude in which extrinsic interventions may not adequately terminate sustained triggered activity.
(10) Flaviu, a two-year-old male about the size of a cocker spaniel, arrived at the zoo from a park in Kent after being separated from his mum and dad for the first time.
(11) Multivariate techniques for LC-DAD data are shown to suffer from inherent limitations of sensitivity for the minor components.
(12) When we reached our summit, or whatever spot was deemed by my father to be of adequately punishing distance from the car to deserve lunch, Dad would invariably find he had forgotten his Swiss army knife (looking back, I begin to doubt he ever had one) and instead would cut cheese into slices with the edge of his credit card.
(13) Not just going to a live show, but that kind of live show, with that kind of audience, the kind where mums and dads either have to tag along or turn up at the end to pick their children up.
(14) "It's made him more real, more of a person for me, whereas when I was a little girl I would say to my friends 'My dad died in the war' but it didn't mean anything to me because I never knew him.
(15) I cook, I save money, I do my own thing.’ Photograph: Antonio Olmos Laura: 'I couldn't live at home with my dad any longer.
(16) There they are, drinking again.’” Harper is a loner – a suburban boy who went trainspotting with his dad; whose asthma stopped him playing ice hockey That scorn appears to have interrupted the clever student’s journey to the top of the class.
(17) "But my dad ran a furniture business, which he lost at the time of the Great Recession before dying of a brain haemorrhage," he says.
(18) The road to gaining nearly 1.2 billion monthly active users has seen the mums, dads, aunts and uncles of the generation who pioneered Facebook join it too, spamming their walls with inspirational quotes and images of cute animals, and (shock, horror) commenting on their kids' photos.
(19) Throughout his life, Dad observed the rule that profanity – effing and blinding as he called it – should be confined to workplaces and other all-male venues where men gathered outside the earshot of women and children.
(20) In his V-neck sweater, dad jeans and white New Balance sneakers, Michael Lewis doesn’t look like a troublemaker.
Nad
Definition:
() Alt. of Nadde
Example Sentences:
(1) One hour after direct mechanical cardiomassage (DMCM) a moderately pronounced edema of the intercellular spaces in the basal compartment of the seminiferous epithelium, normal content of lactate and succinate dehydrogenases, and a certain decrease in the activity of glucose-6-phosphate dehydrogenases and NAD- and NADP-diaphorases were noted.
(2) Transformed mammalian cells express both the usual NADP-dependent trifunctional methylenetetrahydrofolate dehydrogenase-cyclohydrolase-synthetase as well as the bifunctional NAD-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase.
(3) The results are discussed in terms of a two-site model in which separate, but interacting, regions exist on the enzyme to accommodate the adenosine and nicotinamide moieties of NAD, and a single-site model in which the adenosine part of the molecule is bound preferentially and this interacts with the nicotinamide fraction.
(4) The NAD-dependent enzymes (except alpha-GPDH) showed a stronger reactivity in the proximal tubules, while the NADP-dependent ones were more reactive in the thick limb of Henle's loop and distal convoluted tubules.
(5) In contrast, AMP and adenosine did not alter NAD glycohydrolase activity or affect subunit structure.
(6) With cortisol and cortisol-21-aldehyde, product inhibition patterns showed only slope effects with steroid product and NAD+, suggesting a "random" mechanism.
(7) Kinetic studies of glutamate dehydrogenase were made with wide concentration ranges of the coenzymes NAD(+) and NADP(+) and the substrates glutamate and norvaline.
(8) Both substances decreased the concentrations of NAD(+) in the islet cells to about 10% of the control values within 2h after injection.
(9) We investigated the denaturation of tetrameric 20 beta-hydroxysteroid dehydrogenase (20R)-17 beta,20 beta,21-trihydroxysteroid:NAD+ oxidoreductase, EC 1.1.1.53) to find out whether intermediate states are formed during the process.
(10) On subfractionation of this crude mitochondrial fraction with continuous sucrose density gradients, most of the activity of the three enzymes was found at a higher density than NAD+-isocitrate dehydrogenase and at about the same density as glutamate dehydrogenase, confirming earlier reported data for acetyl-CoA synthase.
(11) The effect of dicoumarol on glucuronidation of 3-OH-benzo(a)pyrene (BP) appears to be due to inhibition of UDPglucuronosyltransferase (UDPGT) and not to an inhibited DT-diaphorase (NAD(P)H:quinone oxidoreductase); to date the only enzyme known to be inhibited by dicoumarol.
(12) The increase in concentration of organic cosolvents results in a 2-2.5-fold increase of the maximal reaction rate and a decrease of Michaelis constant for formate of NAD(+)-dependent formate dehydrogenase from methylotrophic bacteria Pseudomonas sp.
(13) Furthermore, NADP was over 1000-fold more potent than NAD in inhibiting the enzyme competitively with respect to NADH.
(14) The possible participation of a Ca(2+)-induced activation of NAD-isocitrate dehydrogenase in this process was investigated.
(15) A 4.1-kb EcoRI fragment which includes the gene (gldA) encoding a glycerol dehydrogenase (G1DH; EC 1.1.1.6; glycerol:NAD oxidoreductase) from Bacillus stearothermophilus var.
(16) It is supposed that the stimulating effect of lactate with NAD+ on the mitochondria respiration is not so much a result of the membrane-damaged action as a result of oxidation of lactate dehydrogenase reaction products: phosphorylative oxidation of pyruvate and nonconjugated oxidation of NADH.
(17) In the presence of glycolate (glyoxylate), and NADH and NAD alone or together in physiological proportions, the rate of serine-to-glycerate conversion was enhanced and sustained by the addition of malate.
(18) Virazole 5'-phosphate was subsequently found to be a potent competitive inhibitor of inosine 5'-phosphate dehydrogenase (IMP:NAD(+) oxidoreductase, EC 1.2.1.14) isolated from Escherichia coli (K(m) = 1.8 x 10(-5) M) with a K(i) of 2.7 x 10(-7) M. Guanosine 5'-phosphate (GMP) was a competitive inhibitor of this enzyme with a K(i) of 7.7 x 10(-5) M. Virazole 5'-phosphate was similarly active against IMP dehydrogenase isolated from Ehrlich ascites tumor cells, with a K(i) of 2.5 x 10(-7) M. The K(m) for this enzyme was 1.8 x 10(-5) M, and the K(i) for GMP was 2.2 x 10(-4) M. These results suggest that the antiviral activity of Virazole might be due to the inhibition of GMP biosynthesis in the infected cell at the step involving the conversion of IMP to xanthosine 5'-phosphate.
(19) The methods described make possible the preparation of fossil samples for light nad transmission electron microscopy.
(20) The activity of soluble NAD-specific hydrogenase was not detected.