(n.) A nickname given to a person of Spanish (or, by extension, Portuguese or Italian) descent.
Example Sentences:
(1) Unlike thiorphan, 5 nmol RB38A alone was able to inhibit [3H]DAGO binding by 60%.
(2) SKF 38393 (1 microM)-stimulated adenylate cyclase activity was strongly reduced (by almost 60%) by the highly selective mu-agonist [D-Ala2, MePhe4, Gly-ol5]-enkephalin (DAGO; EC50 = 0.006 microM) and high concentrations of the selective delta-agonist [D-Ser2(O-tert-butyl), Leu5]-enkephalyl-Thr6 (DSTBU-LET; EC50 = 0.13 microM) but not by the selective delta-agonist [D-penicillamine2, D-penicillamine5]enkephalin (DPDPE).
(3) Centrally administered DADLE also attenuated baroreceptor reflexes, but was approximately 10- to 100-fold less potent than an equimolar amount of DAGO.
(4) 1, male Long-Evans rats were treated with unilateral microinjections of the mu agonist [D-Ala2-MePhe4, Gly-ol5]-enkephalin (DAGO), the delta agonist [D-Pen2, D-Pen5]-enkephalin (DPDPE) or the kappa agonist U50,488H, and the rate and duration of circling behaviour were measured.
(5) Heart rate, but not mean arterial blood pressure, increased in response to DAGO administration into the NTS while no significant cardiovascular changes were noted among the experimental groups in response to DAGO administered into the PVN.
(6) MOR, DAGO and NALO produced mixed effects (i.e., excitation or inhibition) on unit activity; however, the majority of cells examined (67%) were inhibited.
(7) This effect of DAGO was not due to spread to the third ventricle and subsequent diffusion via the CSF to another CNS site, since push-pull perfusion with this dose of DAGO in the region just dorsal to or in the posterior hypothalamus was ineffective in altering LH pulse amplitude.
(8) The mu-agonist DAGO ([D-Ala2,N-MePhe4,Gly-ol5]enkephalin; 0.75 nmol i.c.v.)
(9) Mu and delta receptors were labeled with the selective ligands 3H-DAGO (Tyr- D-Ala-Gly-MePhe-Gly-ol), and 3H-DPDPE (D-Pen2, D-Pen5-enkephalin), respectively, while the kappa receptors were labeled with 3H-(-)bremazocine in the presence of unlabeled DAGO and DPDPE.
(10) Morphine, Leu-enkephalin, D-Ala2, N-methyl-Phe4, Gly-ol5-enkephalin (DAGO) and D-Ser2-Leu-enkephalin-Thr (DSLET) each inhibited the synthesis of cyclic AMP.
(11) The purpose of the present study was firstly to determine whether morphine and (D-Ala2, NMe-Phe4, Gly-ol)-enkephalin (DAGO), a highly selective mu-agonist, increased intracellular free calcium of rat myocytes and secondly to determine whether opioid receptors were involved.
(12) We examined the interactions between glutamate and a selective mu opioid receptor agonist, D-Ala2-MePhe4-Gly-ol5-enkephalin (DAGO), in spinal trigeminal neurons in thin medullary slices of rats.
(13) mu-Receptors' agonist DAGO injection significantly decreased rat mortality in a posthemorrhagic period.
(14) In addition, naloxone antagonized the effect of DAGO.
(15) In non-deprived rats given a choice of water and 0.6% saline, ICV injections of DAGO (1 and 3 nmol) significantly increased the intake of 0.6% saline; baseline water intake was minimal and was unaffected by DAGO.
(16) Receptor autoradiographic studies with 3H-DAGO were carried out in the central gray to find receptor populations differing greatly in density between HAR and LAR mice to parallel their in vivo sensitivity differences: such receptors would then be implicated in mediating in vivo analgesia.
(17) Eighty percent of [3H]-[D-Ala2,D-Leu5] enkephalin (DADLE) binding was displaced by DAGO with high affinity, indicating that a high percentage of [3H]-DADLE binding was at mu-sites.
(18) In untreated animals, morphine and the mu-selective peptide, DAGO, induced relatively long-lasting dose-related decreases in responding, whereas the non-mu agonists, DPDPE and dynorphin, induced only transient effects: response rates increased at low doses and decreased at high doses.
(20) To examine the relative roles of mu 1- and mu 2-receptors in spinal and supraspinal analgesia, we assessed the effects of naloxonazine, naloxone, beta-funaltrexamine (beta-FNA), and ICI-154,129 on tail-flick analgesia produced by intrathecal or intracerebroventricular injections of the highly mu-selective agonist, [D-Ala2,Me-Phe4,Gly(ol)5]enkephalin (DAGO; mu 1 and mu 2), [D-Ser2,Leu5]enkephalin-Thr6 (DSLET; mu 1 and delta), and the selective delta-receptor agonist [D-Pen2,D-Pen5]enkephalin (DPDPE) in mice.
Guido
Definition:
Example Sentences:
(1) But Detre declined to comment on a report on the Guido Fawkes website that Westminster Advisers, run by the Labour supporter and former councillor Dominic Church, organised a cross-party meeting at the end of 2010 which was shown the Crosby Textor research .
(2) So it will have been a wrench for Jez, and his embattled entourage, to have to “cave in”, as the Guardian’s report put it, and suspend the MP from the party after David Cameron (who really should leave the rough stuff to the rough end of the trade) had taunted him at PMQs for not acting sooner when the Guido Fawkes blog republished her ugly comments and the Mail on Sunday got out its trumpet.
(3) "As soon as we have digested the full 2011 statistics, the combination can be redone," said Guido Tonelli , spokesman for the CMS collaboration.
(4) Brazilian finance minister Guido Mantega made his comments in a speech in Sao Paulo last night to Brazilian industrial leaders ahead of presidential elections on Sunday.
(5) Moses admitted that the story, which prompted Newmark’s resignation as a minister, was so serious that Ipso would have investigated it even without the complaint made by Mark Pritchard, one of several Tory MPs contacted by Alex Wickham, a freelance reporter who works for the Guido Fawkes blog .
(6) Photograph: James Drew Turner Guido Schmidt-Traub and Jeffrey Sachs, who head up the UN sustainable development solutions network, say in a working paper for the finance ministers’ conference that it, together with the UN general assembly in September and the UN climate conference in Paris in December, will “forge the sustainable development future of the planet, successful or not”.
(7) After the posting was highlighted by the Guido Fawkes website, Shah released a statement in which she said: “This post from two years ago was made before I was an MP, does not reflect my views and I apologise for any offence it has caused.” Shah is a member of the House of Commons home affairs select committee, which is conducting an inquiry into the rise of antisemitism.
(8) West Germany (3-5-2): Bodo Illgner; Guido Buchwald, Klaus Augenthaler, Jürgen Kohler; Thomas Berthold, Thomas Hässler, Lothar Matthäus, Olaf Thon, Andreas Brehme; Jürgen Klinsmann, Rudi Völler.
(9) Biggest shock of reshuffle so far #reshuffle October 7, 2013 Updated at 2.02pm BST 1.37pm BST Mark Prisk has been sacked as housing minister, Guido Fawkes claims.
(10) She shows her long-time creative collaborator, Guido Costa, with his pregnant wife, Caterina, and later with their daughter, Isabella, and the experimental film-maker Vivienne Dick with her son, Jesse, as well as children she has photographed for Kidswear magazine, with which she has a contract that allows her to choose her own subjects.
(11) In the future search for coalition partners, Merkel will be heavily reliant on the hapless foreign minister and Liberal Democrat leader Guido Westerwelle, while the revitalised Social Democrats and the ever-rising Greens can start dreaming again of the halcyon days under Gerhard Schröder and Joschka Fischer.
(12) But Professor Massimo Egidi, an economist and rector of LUISS Guido Carli, a private university in Rome, dismissed a link between the results and Italy's 43% youth unemployment rate for under 24-year-olds.
(13) Koeman’s agent is Guido Albers who, intriguingly, touted another of his clients – Frank de Boer – for the Everton job last weekend.
(14) October 7, 2013 Guido Fawkes says this runs counter to the supposed theme of the reshuffle.
(15) "The government has not yet decided," said Guido Westerwelle, the German foreign minister and leader of Merkel's junior FDP coalition partner which is against the rescue package.
(16) According to the Guido Fawkes website, the warning said: "There have been a number of articles recently in connection with some of the ways in which the UK intelligence services obtain information from foreign sources.
(17) Germany's foreign minister, Guido Westerwelle, has called the US ambassador to a personal meeting to discuss allegations that US secret services bugged Angela Merkel's mobile phone.
(18) In a statement last night, McBride said he was "shocked and appalled" that Staines had obtained the emails and handed them to newspapers, insisting that he and Draper had already decided "Derek should not take his online efforts down to the level of Guido Fawkes" and that their ideas would not be used.
(19) I am honoured by the opportunity to contribute to this collection of papers dedicated to Professor Guido Pontecorvo on the occasion of his eightieth birthday.
(20) Britain understands that Guido Westerwelle, the German foreign minister, and Radek Sikorski, the Polish foreign minister, are particularly angry with the president, Alexander Lukashenko .