(n.) A nickname given to a person of Spanish (or, by extension, Portuguese or Italian) descent.
Example Sentences:
(1) Unlike thiorphan, 5 nmol RB38A alone was able to inhibit [3H]DAGO binding by 60%.
(2) SKF 38393 (1 microM)-stimulated adenylate cyclase activity was strongly reduced (by almost 60%) by the highly selective mu-agonist [D-Ala2, MePhe4, Gly-ol5]-enkephalin (DAGO; EC50 = 0.006 microM) and high concentrations of the selective delta-agonist [D-Ser2(O-tert-butyl), Leu5]-enkephalyl-Thr6 (DSTBU-LET; EC50 = 0.13 microM) but not by the selective delta-agonist [D-penicillamine2, D-penicillamine5]enkephalin (DPDPE).
(3) Centrally administered DADLE also attenuated baroreceptor reflexes, but was approximately 10- to 100-fold less potent than an equimolar amount of DAGO.
(4) 1, male Long-Evans rats were treated with unilateral microinjections of the mu agonist [D-Ala2-MePhe4, Gly-ol5]-enkephalin (DAGO), the delta agonist [D-Pen2, D-Pen5]-enkephalin (DPDPE) or the kappa agonist U50,488H, and the rate and duration of circling behaviour were measured.
(5) Heart rate, but not mean arterial blood pressure, increased in response to DAGO administration into the NTS while no significant cardiovascular changes were noted among the experimental groups in response to DAGO administered into the PVN.
(6) MOR, DAGO and NALO produced mixed effects (i.e., excitation or inhibition) on unit activity; however, the majority of cells examined (67%) were inhibited.
(7) This effect of DAGO was not due to spread to the third ventricle and subsequent diffusion via the CSF to another CNS site, since push-pull perfusion with this dose of DAGO in the region just dorsal to or in the posterior hypothalamus was ineffective in altering LH pulse amplitude.
(8) The mu-agonist DAGO ([D-Ala2,N-MePhe4,Gly-ol5]enkephalin; 0.75 nmol i.c.v.)
(9) Mu and delta receptors were labeled with the selective ligands 3H-DAGO (Tyr- D-Ala-Gly-MePhe-Gly-ol), and 3H-DPDPE (D-Pen2, D-Pen5-enkephalin), respectively, while the kappa receptors were labeled with 3H-(-)bremazocine in the presence of unlabeled DAGO and DPDPE.
(10) Morphine, Leu-enkephalin, D-Ala2, N-methyl-Phe4, Gly-ol5-enkephalin (DAGO) and D-Ser2-Leu-enkephalin-Thr (DSLET) each inhibited the synthesis of cyclic AMP.
(11) The purpose of the present study was firstly to determine whether morphine and (D-Ala2, NMe-Phe4, Gly-ol)-enkephalin (DAGO), a highly selective mu-agonist, increased intracellular free calcium of rat myocytes and secondly to determine whether opioid receptors were involved.
(12) We examined the interactions between glutamate and a selective mu opioid receptor agonist, D-Ala2-MePhe4-Gly-ol5-enkephalin (DAGO), in spinal trigeminal neurons in thin medullary slices of rats.
(13) mu-Receptors' agonist DAGO injection significantly decreased rat mortality in a posthemorrhagic period.
(14) In addition, naloxone antagonized the effect of DAGO.
(15) In non-deprived rats given a choice of water and 0.6% saline, ICV injections of DAGO (1 and 3 nmol) significantly increased the intake of 0.6% saline; baseline water intake was minimal and was unaffected by DAGO.
(16) Receptor autoradiographic studies with 3H-DAGO were carried out in the central gray to find receptor populations differing greatly in density between HAR and LAR mice to parallel their in vivo sensitivity differences: such receptors would then be implicated in mediating in vivo analgesia.
(17) Eighty percent of [3H]-[D-Ala2,D-Leu5] enkephalin (DADLE) binding was displaced by DAGO with high affinity, indicating that a high percentage of [3H]-DADLE binding was at mu-sites.
(18) In untreated animals, morphine and the mu-selective peptide, DAGO, induced relatively long-lasting dose-related decreases in responding, whereas the non-mu agonists, DPDPE and dynorphin, induced only transient effects: response rates increased at low doses and decreased at high doses.
(20) To examine the relative roles of mu 1- and mu 2-receptors in spinal and supraspinal analgesia, we assessed the effects of naloxonazine, naloxone, beta-funaltrexamine (beta-FNA), and ICI-154,129 on tail-flick analgesia produced by intrathecal or intracerebroventricular injections of the highly mu-selective agonist, [D-Ala2,Me-Phe4,Gly(ol)5]enkephalin (DAGO; mu 1 and mu 2), [D-Ser2,Leu5]enkephalin-Thr6 (DSLET; mu 1 and delta), and the selective delta-receptor agonist [D-Pen2,D-Pen5]enkephalin (DPDPE) in mice.
Spanish
Definition:
(a.) Of or pertaining to Spain or the Spaniards.
(n.) The language of Spain.
Example Sentences:
(1) It is the oldest medical journal in South America and the second in antiquity published in Spanish, after the Gaceta de México.
(2) MI6 introduced him to the Spanish intelligence service and in 2006 he travelled to Madrid.
(3) Total costs of building the three missile destroyers in Australia will amount to more than $9bn, approximately three times the cost of buying the ships ready made from Spanish company Navantia, The Australian reported on Friday .
(4) The young European idealist who helped Leon Brittan, the British EU commissioner, to negotiate Chinese entry to the World Trade Organisation, also found his Spanish lawyer wife in Brussels.
(5) The Mexican-Americans of Starr County, Texas, classified by sex and birthplace, were studied to determine the extent of genetic variation and contributions from ancestral populations such as Spanish, Amerindian and West African.
(6) Head chef Christopher Gould (a UK Masterchef quarter-finalist) puts his own stamp on traditional Spanish fare with the likes of mushroom-and-truffle croquettes and suckling Málaga goat with couscous.
(7) Corruption scandals have left few among the Spanish ruling class untainted, engulfing politicians on the left and right of the spectrum, as well as businesses, unions, football clubs and even the king’s sister .
(8) Sometimes it can seem as if the history of the City is the history of its crises and disasters, from the banking crisis of 1825 (which saw undercapitalised banks collapse – perhaps the closest historic parallel to the contemporary credit crunch), through the Spanish panic of 1835, the railway bust of 1837, the crash of Overend Gurney, the Kaffir boom, the Westralian boom, the Marconi scandal, and so on and on – a theme with endless variations.
(9) On 26 April 1937 this market town was obliterated in three hours of bombing by Nazi planes, allies of Generalísimo Francisco Franco’s fascists in the Spanish civil war.
(10) The competition comes a month after the Spanish government put forward legislation that aims to sharply limit women's access to abortion across the country.
(11) The only Spanish voice heard in Catalonia is that of the Madrid government, which seems oblivious to the implications of the groundswell of pro-independence sentiment, much as at Westminster politicians missed the shift in Scottish opinion until just before the referendum.
(12) The State-Trait Anxiety Inventory questionnaire, recently validated in Spanish, was used to measure the students' anxiety associated with the examinations.
(13) Zidane’s first game proper will be on Saturday at home against Deportivo La Coruna in the Spanish league.
(14) Picardo said that he was in frequent "fluid" contact with local politicians in the Spanish border town of La Linea and other areas where the more than 4,000 Spaniards who work in the peninsula live.
(15) The genetic distances separating 14 Spanish goat breeds are calculated from gene frequency data of 14 genetic blood markers (GSH, Ke, Hb, Dia, Ct, MDH, CA, X, NP, Alp, Am, Cp, Tf and Al).
(16) The Cape Ray, a 648ft converted car ferry, has been waiting at the Spanish port of Rota for four months for the extraction of chemical weapons from Syria to be completed.
(17) Parents appear at provincial court in Málaga, part of the process to transfer them to the Spanish capital, Madrid, for extradition hearing on Monday.
(18) Spanish renaissance In contrast, Spanish has held up remarkably well, due to its resilience at GCSE and growing awareness of the number of people around the world who speak it.
(19) • The Spanish government has warned the US that revelations of widespread spying by the National Security Agency could, if confirmed, “ lead to a breakdown in the traditional trust ” between the two countries.
(20) Miklos Haraszti, whom I encountered in Budapest, had the looks of a small Spanish grandee in some Velázquez painting; dark, unnervingly handsome, serene.