(v. t.) To make damp or moist; to make slightly wet.
(v. t.) To depress; to check; to make dull; to lessen.
(v. i.) To become damp; to deaden.
Example Sentences:
(1) Toxic effects of glucocorticoids on bone contribute to the pathogenesis of osteonecrosis, increase the risk for fractures by decreasing cancellous bone mass and synthesis of bone matrix, and dampen the linear growth response in pediatric recipients.
(2) These findings indicate that sympathetic-adrenal medullary responses are dampened considerably in animals exposed to a highly predictable regimen of chronic intermittent stress.
(3) 11.12am BST Here's my colleague Angela Monaghan 's news story on the manufacturing data: Heavy rainfall failed to dampen Britain's manufacturing sector in February with output growing much more strongly than expected, boosting the outlook for the wider economy.
(4) Since prosthetic meniscal replacement may be performed in the setting of normal articular cartilage, a prosthesis will be required to match the exact joint configuration, induce the same lubricity, produce the same coefficient of friction, and absorb and dampen the same joint forces (without incurring significant creep or abrasion) as does the normal meniscus.
(5) The subcupular meshwork may play an important role in transmitting the shear strain of the otolithic membrane to all the ciliary bundles and may also exert an additional dampening effect to prevent unwanted vibration.
(6) MPC member Andrew Sentance has argued the bank risks stoking inflationary pressures if it adopts a looser monetary policy and should increase interest rates to dampen demand.
(7) In addition, there is evidence that both receptor-operated Ca2+ and potential-operated Ca2+ channels may be impaired because the responses to norepinephrine and KCl are both dampened in diabetic aortae.
(8) The reduced phacoemulsification incision size in combination with a scleral pocket closed with a continuous single knotted 10-0 monofilament nylon suture under tonometric and keratometric control significantly dampens the changes in corneal astigmatism during the early and late postoperative periods.
(9) This dampened response to ethanol for men at high future risk for alcoholism was not observed after challenges with two different doses of diazepam.
(10) In the Purkinje cell bodies, however, the metabolic stress was dampened; glucose concentrations decreased, but the levels of ATP were maintained and, to a lesser extent, those of P-creatine.
(11) In this series, the association MCA curve dampened and PTI lower than 0.90 is the evidence of a more than 90% stenosis, except in 2 atheromatous and symptomatic occlusions.
(12) Although growth-retarding cell to cell interactions are also clearly operative in growing FRTL-5 cells, they are less effective than those dampening the replication rate of the thyrocytes within the monolayer hull of normal follicles.
(13) It said that a widening of interest rate spreads could add to the cost of new borrowing, acting to dampen demand.
(14) Prior exposure to PGE1 minimally inhibited airway responses but when given simultaneously with antigen, it either selectively inhibited some or dampened all pulmonary function abnormalities.
(15) There appeared to be a concerted attempt by both countries on Sunday to dampen down any controversy and return to business as usual.
(16) But she is nervous and what she is doing is dampening speculation to make the task less stressful.
(17) Phenobarbital by inhibiting PIP-kinase may reduce the membrane concentration of PIP2 and thus dampen the stimulus-response which leads to the hydrolysis of PIP2 and the formation of the second messenger, inositol-1,4,5-trisphosphate (IP3), involved in mobilization of intracellular Ca2+.
(18) Alcohol's Stress-Response-Dampening (SRD) effect has been the subject of much research, but little has been done to examine the effects of drinking alcohol after experiencing a stressor (Stress-Response-Recovery; SRR).
(19) Eosinophils have also been involved in the process of the replenishment of mediators by dampening the synthesis of mediators in mast cells.
(20) Failure to respond to influenza vaccination correlated with a decreased number and percentage of IgD-bearing PBL and a dampened lymphocyte response to PWM in a subset of healthy aged volunteers.
Kindle
Definition:
(v. t. & i.) To bring forth young.
(v. t.) To set on fire; to cause to burn with flame; to ignite; to cause to begin burning; to start; to light; as, to kindle a match, or shavings.
(v. t.) Fig.: To inflame, as the passions; to rouse; to provoke; to excite to action; to heat; to fire; to animate; to incite; as, to kindle anger or wrath; to kindle the flame of love, or love into a flame.
(v. i.) To take fire; to begin to burn with flame; to start as a flame.
(v. i.) Fig.: To begin to be excited; to grow warm or animated; to be roused or exasperated.
Example Sentences:
(1) The anticonvulsant properties of the endogenous excitatory amino acid antagonist, kynurenic acid (KYA), were studied in prepubescent and adult rats using the amygdaloid kindling model of epilepsy.
(2) For the purpose of contributing methodologically to experimental research on epilepsy, we investigated whether a difference exists in kindling development between acute and chronic preparations using identical species of animals, kindled brain tissues, stimulus intervals, and intensities.
(3) The kainate and quisqualate types of excitatory amino acid receptor were visualized autoradiographically in brain sections from rats kindled by stimulating the angular bundle.
(4) A corrective effect of Nicotinamide on oxidation processes in ganglion and neuroglial cells of cerebral cortex sensorimotor zone in "kindling" phenomenon was studied in the experiments on mice of C57BL line.
(5) PHT, CBZ, VPA, and CZP, SK&F 89976-A and SK&F 100330-A inhibited seizures in corneally kindled rats.
(6) The inhibitory effect of serotonin on the kindling model of epilepsy was investigated in the adult rat.
(7) In the second experiment, 15- and 30-day-old rats underwent unilateral carotid ligation followed by kindling in the ipsilateral amygdala.
(8) If Obama is your new iPad, Sarah Palin is your old Kindle.
(9) Electrical amygdaloid kindling was carried out with a 15 min inter-stimulus interval (ISI) in a control situation with intravenous (i.v.)
(10) We suggest that the NE-dependent mechanism responsible for the seizure suppression observed to follow concurrent, alternate stimulation and the suppression of seizure development using single-site kindling paradigms may be the same.
(11) GABAergic neurons and terminals are also increased in the hippocampus of seizure-sensitive gerbils, and kindling of the hippocampus and amygdala appears to enhance GABAergic inhibitory mechanisms.
(12) Based on an hypothesis that links electrical kindling in the limbic system (leading to seizures) to reverse tolerance or sensitivity to cocaine's effects, carbamazepine is being tested as a treatment for human cocaine users.
(13) reversed the increase in locomotion and elevation of multiple squeak thresholds in the bilaterally kindled rats.
(14) In fully kindled animals a stimulus-induced generalized seizure gave rise to a three-fold increase of noradrenaline levels in the stimulated hippocampus as compared to baseline levels (15-min samples).
(15) In the present work no significant differences were found between the behaviour of FG7142-kindled rats and vehicle-treated controls in social interaction test, elevated plus maze, or the Vogel conflict test of anxiety or in tests of home cage aggression or startle responses.
(16) Amygdaloid kindling of rats produced an increase in hippocampal Met5-enkephalin-Arg6-Gly7-Leu8 and cholecystokinin immunoreactivities and simultaneously a decrease in dynorphin A1-8 content.
(17) The data suggest that GABA-T inhibitors, such as vigabatrin, differ from most antiepileptic drugs previously tested in the kindling model in that they may produce both anticonvulsant and proconvulsant effects at the same dose in the same animal as a function of time after administration.
(18) However, the concentration of Asp decreased depending on the kindling stage, reaching the lowest value of 33% in comparison with the normal value.
(19) Thus, electrophysiological alterations within the first synaptic relay of the hippocampal trisynaptic circuit, the dentate gyrus, cannot explain the long duration of the kindling effect.
(20) In brightness discrimination reaction (BDR) the learning performance of PTZ-kindled animals was not influenced.