(n.) That which is due from one person to another, whether money, goods, or services; that which one person is bound to pay to another, or to perform for his benefit; thing owed; obligation; liability.
(n.) A duty neglected or violated; a fault; a sin; a trespass.
(n.) An action at law to recover a certain specified sum of money alleged to be due.
Example Sentences:
(1) In the bars of Antwerp and the cafes of Bruges, the talk is less of Christmas markets and hot chocolate than of the rising cost of financing a national debt which stands at 100% of annual national income.
(2) Madrid now hopes that a growing clamour for future rescues of Europe's banks to be done directly, without money going via governments, may still allow it to avoid accepting loans that would add to an already fast-growing national debt.
(3) Profit for the second quarter was £27.8m before tax but the club’s astronomical debt under the Glazers’ ownership stands at £322.1m, a 6.2% decrease on the 2014 level of £343.4m.
(4) The government did not spell out the need for private holders of bank debt to take any losses – known as haircuts – under its plans but many analysts believe that this position is untenable.
(5) However, civil society groups have raised concerns about the ethics of providing ‘climate loans’ which increase the country’s debt burden.
(6) The pump function of the heart (oxygen debt dynamics), the anaerobic threshold (complex of gas analytical indices), and the efficacy of blood flow in lesser circulation (O2 consumption plateau) were appraised.
(7) In the UK, George Osborne used this to his advantage, claiming "Britain faces the disaster of having its international credit rating downgraded" even after Moody's ranked UK debt as "resilient".
(8) Thus, the decreased hyperemic response after arrest suggests a reduced energetic debt with CSC compared with ARC and may indicate superior myocardial protection with CSC.
(9) It was the ease with which minor debt could slide into a tangle of hunger and despair.
(10) Most (86 percent) had educational debt (mean = $20,500), and more than half of those with debt were making loan payments.
(11) Silvio Berlusconi's government is battling to stay in the eurozone against mounting odds – not least the country's mountain of state debt, which is the largest in the single currency area.
(12) However in a repeat of the current standoff over the federal budget, the conservative wing of the Republican party is threatening to exploit its leverage over raising the debt ceiling to unpick Obama's healthcare reforms.
(13) It would cost their own businesses hundreds of millions of pounds in transaction costs, it would blow a massive hole in their balance of payments, it would leave them having to pick up the entirety of UK debt.
(14) Nevertheless we know that there will remain a large number of borrowers with payday loans who are struggling to cope with their debts, and it is essential that these customers are signposted to free debt advice.
(15) Finally, there is that pesky matter of public debt, which is still 90% of eurozone GDP.
(16) The ONS said it was possible that these one-off items and a rise in tax receipts in January could bring the overall debt figure within the OBR's £80.5bn forecast.
(17) This causes a time lag, with money continuing to be taken until the SLC is made aware that the debt has been settled.
(18) Unsecured lending rose slightly during the month, with outstanding debt increasing by £331m, after contracting by £114m in April.
(19) He said: "Advanced economies are still confronted with high levels of public and private debt, which act as brakes on the recovery.
(20) Portugal's slide towards a Greek-style second bailout accelerated after its principal private lenders indicated that they were growing weary of assurances from Lisbon that it could get on top of the country's debts.
Unbind
Definition:
(v. t.) To remove a band from; to set free from shackles or fastenings; to unite; to unfasten; to loose; as, unbind your fillets; to unbind a prisoner's arms; to unbind a load.
Example Sentences:
(1) Thus, although the fast sodium inactivation process is not required for tonic and use-dependent block of INa by disopyramide, it contributes to the fast phase of block development and unbinding from use-dependent block.
(2) Two calcium antagonistic drugs, nifedipine and mesudipine, were investigated and as a result averaged rate constants of binding and unbinding were evaluated.
(3) Physical theories have been developed to describe many aspects of their conformational behaviour, such as the preferred shapes and shape transformations of closed vesicles, and the shape fluctuations, random-surface configurations, and adhesion and unbinding of interacting membranes.
(4) Assuming a reversible one-to-one binding reaction, the time course of DHO binding and unbinding was analysed under a variety of conditions.
(5) Sanguinarine may produce a K+-like effect upon the Na pump with consequent unbinding of ouabain.
(6) The rate constants for binding and unbinding of ATP were estimated from the dependence of the mean open time on [ATP] and from the Ki.
(7) The rate for unbinding during depolarization was independent of pHo.
(8) We suggest that these conformational changes arise from the unbinding to DNA of certain basic tails of histone(s), and that a competition for DNA binding locations exists upon the reassociation.
(9) These findings suggest than AN-132 has use dependent inhibitory action on the fast sodium channel by binding to the channel mainly during its activated state and that the unbinding rate of the drug during diastole is very slow.
(10) Because in most cases these fit a single exponential with a mean open duration like that of modified channels, we conclude that voltage-dependent toxin unbinding produced a mixed population of unmodified and modified openings.
(11) The extent of the contribution of the process of agonist binding and unbinding to adenylate cyclase activation has not been demonstrated or quantified.
(12) It is interesting that encainide and flecainide unbind slowly (15-20 seconds), whereas lidocaine and moricizine unbind rapidly (0.2-1.3 seconds).
(13) Therefore, sodium channel states regulate the binding and unbinding behaviour of antiarrhythmic drugs.
(14) Such [Ca2+]i-transients in muscle are actually subcellular spatio-temporal events that are determined dynamically by i) diffusional fluxes of Ca2+, ii) by the binding or unbinding of Ca2+ to ligands such as troponin c and calmodulin, and iii) by the various cellular processes, such as release of Ca2+ from sarcoplasmic reticulum, that produce fluxes of Ca2+ across the membranes bounding organelles or the cell.
(15) According to the model, RAC109-I and RAC109-II have significantly different unbinding rate constants for channels when they exist predominantly in rested, activated, or inactivated states, as well as significantly different binding rate constants when channels are activated.
(16) We conclude that binding and unbinding of one molecule of ATP determine the gating of ATP-sensitive K+ channel.
(17) The dissociation rate constant of DHO unbinding remained unchanged (approximately 0.06 s-1).
(18) Estimates of binding and unbinding rate constants for the sodium channel during the action potential plateau and after repolarization were of the same order as previous results obtained using microelectrode methods in vitro.
(19) Increasing the concentration of drug increased the rate of binding but had little or no effect on unbinding, as expected for a simple bimolecular reaction.
(20) Binding and unbinding of MK-801 seems to be possible only if the N-Me-D-Asp-operated channel is in the transmitter-activated state: MK-801 was effective only when applied simultaneously with N-Me-D-Asp, and recovery from MK-801 blockade was speeded by continuous exposure to N-Me-D-Asp [time constant (tau) approximately equal to 90 min at -70 to -80 mV].