(v. i.) To bend, or lean downward; to take a downward direction; to bend over or hang down, as from weakness, weariness, despondency, etc.; to condescend.
(v. i.) To tend or draw towards a close, decay, or extinction; to tend to a less perfect state; to become diminished or impaired; to fail; to sink; to diminish; to lessen; as, the day declines; virtue declines; religion declines; business declines.
(v. i.) To turn or bend aside; to deviate; to stray; to withdraw; as, a line that declines from straightness; conduct that declines from sound morals.
(v. i.) To turn away; to shun; to refuse; -- the opposite of accept or consent; as, he declined, upon principle.
(v. t.) To bend downward; to bring down; to depress; to cause to bend, or fall.
(v. t.) To cause to decrease or diminish.
(v. t.) To put or turn aside; to turn off or away from; to refuse to undertake or comply with; reject; to shun; to avoid; as, to decline an offer; to decline a contest; he declined any participation with them.
(v. t.) To inflect, or rehearse in order the changes of grammatical form of; as, to decline a noun or an adjective.
(v. t.) To run through from first to last; to repeat like a schoolboy declining a noun.
(v. i.) A falling off; a tendency to a worse state; diminution or decay; deterioration; also, the period when a thing is tending toward extinction or a less perfect state; as, the decline of life; the decline of strength; the decline of virtue and religion.
(v. i.) That period of a disorder or paroxysm when the symptoms begin to abate in violence; as, the decline of a fever.
(v. i.) A gradual sinking and wasting away of the physical faculties; any wasting disease, esp. pulmonary consumption; as, to die of a decline.
Example Sentences:
(1) Direct fetal digitalization led to a reduction in umbilical artery resistance, a decline in the abdominal circumference from 20.3 to 17.8 cm, and resolution of the ascites within 72 h. Despite this dramatic response to therapy, fetal death occurred on day 5 of treatment.
(2) This trend appeared to reverse itself in the low dose animals after 3 hr, whereas in the high dose group, cardiac output continued to decline.
(3) Our results suggest that the peripheral sensitivity to hypoxia declined more than that to CO2, implying a peripheral chemoreceptor origin for hypoxic ventilatory decline.
(4) By 24 hr, rough endoplasmic reticulum in thecal cells increased from 4.2 to 7% of cell volume, while the amount in granulosa cells increased from less than 3.5% to more than 10%; the quantity remained relatively constant in the theca but declined to prestimulation values in the granulosa layer.
(5) Here we show that this induction of AP-2 mRNA is at the level of transcription and is transient, reaching a peak 48-72 hr after the addition of RA and declining thereafter, even in the continuous presence of RA.
(6) We studied the hemodynamic changes caused by bronchoscopy under LA in mechanically ventilated patients and the effect of LA on the endoscopic decline in arterial pO2.
(7) Comparison of developmental series of D. merriami and T. bottae revealed that the decline of the artery in the latter species is preceded by a greater degree of arterial coarctation, or narrowing, as it passes though the developing stapes.
(8) Foetal serum TSH concentration declined significantly between 20 and 21 days of gestation, reached a low level at delivery, and remained low for several days after birth.
(9) The decline in the frequency of serious complications was primarily due to a decrease in the proportion of patients with open fractures treated with plate osteosynthesis from nearly 50% to 19%.
(10) Both gp175 and gp250 showed the greatest increase in fucosylation at 10(-5) M, which was also the dose at which RA induced laminin maximally, while the fucosylation of gp400 was greatest at 10(-8) M RA and declined at higher concentrations.
(11) Lambing rates approach 1.5 lambs per ewe per year, but a death rate of 23 per cent and an offtake of 27 per cent, means that flock numbers are probably slightly declining.
(12) In the absence of haemodialysis, the decline in plasma concentrations of lisinopril and enalaprilat was extremely slow and plasma concentrations were generally high.
(13) Steroid-treated steers showed a slight decline in synthesis which was significant (P less than 0.05) at week +5 post-implant while amino acid oxidation was significantly lower at weeks +2 (P less than 0.01) and +5 (P less than 0.05) compared with control animals.
(14) Following thawing, the initial motility index (MI) scores of mf cryopreserved by either method were not significantly different from untreated controls; however, over a period of 15 days in culture the MI scores of both cryopreserved groups showed a small but significant overall decline, with the methanol technique producing the lowest scores.
(15) The last stems from trends such as declining birth rate, an increasingly mobile society, diminished importance of the nuclear family, and the diminishing attractiveness of professions involved with providing maintenance care.
(16) Both strong-stop DNAs are made early during in vitro reactions and decline in concentration later, consistent with postulated roles as initiators of long minus- and plus-strand DNA.
(17) Further, four of five patients long after PTRA remained normotensive, and in all patients plasma renin levels declined.
(18) Initial exposure of cells to low concentrations of either H2O2 or xanthine oxidase resulted in a transient increase in membrane potential relative to control cells (P less than 0.001), followed by an exponential decline in potential (P less than 0.001).
(19) How big tobacco lost its final fight for hearts, lungs and minds Read more Shares in Imperial closed down 1% and British American Tobacco lost 0.75%, both underperforming the FTSE100’s 0.3% decline.
(20) However, cAMP also has posttranscriptional effects on the enzyme's synthesis, as evidenced by the 4- to 5-fold enhanced decline seen when cultured hepatoma cells are exposed to cAMP and transcription is inhibited.
Downward
Definition:
(adv.) Alt. of Downwards
(a.) Moving or extending from a higher to a lower place; tending toward the earth or its center, or toward a lower level; declivous.
(a.) Descending from a head, origin, or source; as, a downward line of descent.
(a.) Tending to a lower condition or state; depressed; dejected; as, downward thoughts.
Example Sentences:
(1) Over a period of 9 months a 12-year-old girl spontaneously developed a palpable cystic tumor in the upper eye lid which led to an indentation and downward displacement of the globe.
(2) Cerebral angiogram displayed a contralateral shift and an unrolling of the anterior cerebral artery, a lateral stretch of middle cerebral artery, a downward stretch of anterior choroidal artery and a tumor stain fed by the Heubner artery.
(3) In this study downward gaze was more severely disturbed than upward gaze.
(4) Business rates: pressure grows for total rethink on controversial tax Read more Meanwhile the downwards press on aggregate council funding is unremitting.
(5) downward occupational and downward social drift, premature retirement and achievement of the expected social development.
(6) In all the RIAs, the dose-response curves obtained on delayed addition by 24 to 48 h of labeled antigens (curves B), were shifted downwards and to the left of those obtained on simultaneous addition of the reagents (curves A), resulting in improved sensitivity of the assay.
(7) A downward protraction force produced relatively uniform stress distributions, indicating the importance of the force direction in determining the stress distributions from various orthopedic forces.
(8) Pregnant women showed an overall downward trend in susceptibility to rubella (from 4.2% at the beginning of 1984 to 3.0% at the end of 1986), and a similar decline was seen in the two other categories.
(9) Put simply, there would have to be evidence that ultra-low oil prices are having only a temporary downward impact on inflation and have helped disguise upward pressure on wages caused by falling unemployment.
(10) With systole there is downward (caudal) flow of CSF in the aqueduct of Sylvius, the foramen of Magendie, the basal cisterns and the dorsal and ventral subarachnoid spaces while during diastole, upward (cranial) flow of CSF in these same structures is seen.
(11) The company's value lies in its FM licence for London, with the audience for its national AM licence spiralling downwards in recent years.
(12) Although the muscles of untreated children also showed shifts of mean frequency to lower frequency values as a function of time, there was a greater downward shift of mean frequency in those treated with functional appliances.
(13) Assuming no future environmental or lifestyle changes, the upward trend in age-adjusted mortality rates, which averaged 2 to 3% per annum since 1950, is projected to discontinue and bend downward by the second decade of the 21st century.
(14) That does not mean that natural ice variability cannot bring it back again, but the trend, we think, will be downward."
(15) These findings suggest that the response to a downward shift of frequency with an amplitude increase results from new activation due to an apical extension of the envelope of the traveling wave and thus represents the activity in a restricted area of the basilar membrane.
(16) The technique consists of wide undermining of supranasal and paranasal skin, use of composite auricular grafts from the ear to lengthen the upper lateral cartilages, use of a chondromucosal septal flap for lengthening the septum, and postoperative downward taping to assure adequate stretching of dorsal skin for the first-stage procedure.
(17) The virus initially appeared within certain keratinocytes, sometimes surrounded by keratinocytes whose surfaces were also positive for the antigens, in the lower epidermal layers including the hair follicles, and then extended upward to the entire epidermis and downward to the sebaceous glands 1-2 days later, when no macroscopic skin lesion was seen.
(18) Erythrocyte sedimentation highly increased leucocyte retention in vertical columns with a downward flow, whereas in slightly tilted columns with an upward flow, the retention was reduced.
(19) Chorismate mutase was also inhibited by prephenate, which caused downward double-reciprocal plots and a Hill coefficient of n = 0.7, evidence for negative cooperativity.
(20) The Saudis and other Gulf states still support rebel fighting formations – as much because of inertia and hostility to Iran as anything else – but western backing is on a downward trajectory as concerns mount about the risks of blowback from al-Qaida-linked groups.