(v. i.) To bend, or lean downward; to take a downward direction; to bend over or hang down, as from weakness, weariness, despondency, etc.; to condescend.
(v. i.) To tend or draw towards a close, decay, or extinction; to tend to a less perfect state; to become diminished or impaired; to fail; to sink; to diminish; to lessen; as, the day declines; virtue declines; religion declines; business declines.
(v. i.) To turn or bend aside; to deviate; to stray; to withdraw; as, a line that declines from straightness; conduct that declines from sound morals.
(v. i.) To turn away; to shun; to refuse; -- the opposite of accept or consent; as, he declined, upon principle.
(v. t.) To bend downward; to bring down; to depress; to cause to bend, or fall.
(v. t.) To cause to decrease or diminish.
(v. t.) To put or turn aside; to turn off or away from; to refuse to undertake or comply with; reject; to shun; to avoid; as, to decline an offer; to decline a contest; he declined any participation with them.
(v. t.) To inflect, or rehearse in order the changes of grammatical form of; as, to decline a noun or an adjective.
(v. t.) To run through from first to last; to repeat like a schoolboy declining a noun.
(v. i.) A falling off; a tendency to a worse state; diminution or decay; deterioration; also, the period when a thing is tending toward extinction or a less perfect state; as, the decline of life; the decline of strength; the decline of virtue and religion.
(v. i.) That period of a disorder or paroxysm when the symptoms begin to abate in violence; as, the decline of a fever.
(v. i.) A gradual sinking and wasting away of the physical faculties; any wasting disease, esp. pulmonary consumption; as, to die of a decline.
Example Sentences:
(1) Direct fetal digitalization led to a reduction in umbilical artery resistance, a decline in the abdominal circumference from 20.3 to 17.8 cm, and resolution of the ascites within 72 h. Despite this dramatic response to therapy, fetal death occurred on day 5 of treatment.
(2) This trend appeared to reverse itself in the low dose animals after 3 hr, whereas in the high dose group, cardiac output continued to decline.
(3) Our results suggest that the peripheral sensitivity to hypoxia declined more than that to CO2, implying a peripheral chemoreceptor origin for hypoxic ventilatory decline.
(4) By 24 hr, rough endoplasmic reticulum in thecal cells increased from 4.2 to 7% of cell volume, while the amount in granulosa cells increased from less than 3.5% to more than 10%; the quantity remained relatively constant in the theca but declined to prestimulation values in the granulosa layer.
(5) Here we show that this induction of AP-2 mRNA is at the level of transcription and is transient, reaching a peak 48-72 hr after the addition of RA and declining thereafter, even in the continuous presence of RA.
(6) We studied the hemodynamic changes caused by bronchoscopy under LA in mechanically ventilated patients and the effect of LA on the endoscopic decline in arterial pO2.
(7) Comparison of developmental series of D. merriami and T. bottae revealed that the decline of the artery in the latter species is preceded by a greater degree of arterial coarctation, or narrowing, as it passes though the developing stapes.
(8) Foetal serum TSH concentration declined significantly between 20 and 21 days of gestation, reached a low level at delivery, and remained low for several days after birth.
(9) The decline in the frequency of serious complications was primarily due to a decrease in the proportion of patients with open fractures treated with plate osteosynthesis from nearly 50% to 19%.
(10) Both gp175 and gp250 showed the greatest increase in fucosylation at 10(-5) M, which was also the dose at which RA induced laminin maximally, while the fucosylation of gp400 was greatest at 10(-8) M RA and declined at higher concentrations.
(11) Lambing rates approach 1.5 lambs per ewe per year, but a death rate of 23 per cent and an offtake of 27 per cent, means that flock numbers are probably slightly declining.
(12) In the absence of haemodialysis, the decline in plasma concentrations of lisinopril and enalaprilat was extremely slow and plasma concentrations were generally high.
(13) Steroid-treated steers showed a slight decline in synthesis which was significant (P less than 0.05) at week +5 post-implant while amino acid oxidation was significantly lower at weeks +2 (P less than 0.01) and +5 (P less than 0.05) compared with control animals.
(14) Following thawing, the initial motility index (MI) scores of mf cryopreserved by either method were not significantly different from untreated controls; however, over a period of 15 days in culture the MI scores of both cryopreserved groups showed a small but significant overall decline, with the methanol technique producing the lowest scores.
(15) The last stems from trends such as declining birth rate, an increasingly mobile society, diminished importance of the nuclear family, and the diminishing attractiveness of professions involved with providing maintenance care.
(16) Both strong-stop DNAs are made early during in vitro reactions and decline in concentration later, consistent with postulated roles as initiators of long minus- and plus-strand DNA.
(17) Further, four of five patients long after PTRA remained normotensive, and in all patients plasma renin levels declined.
(18) Initial exposure of cells to low concentrations of either H2O2 or xanthine oxidase resulted in a transient increase in membrane potential relative to control cells (P less than 0.001), followed by an exponential decline in potential (P less than 0.001).
(19) How big tobacco lost its final fight for hearts, lungs and minds Read more Shares in Imperial closed down 1% and British American Tobacco lost 0.75%, both underperforming the FTSE100’s 0.3% decline.
(20) However, cAMP also has posttranscriptional effects on the enzyme's synthesis, as evidenced by the 4- to 5-fold enhanced decline seen when cultured hepatoma cells are exposed to cAMP and transcription is inhibited.
Heteroclite
Definition:
(a.) Deviating from ordinary forms or rules; irregular; anomalous; abnormal.
(n.) A word which is irregular or anomalous either in declension or conjugation, or which deviates from ordinary forms of inflection in words of a like kind; especially, a noun which is irregular in declension.
(n.) Any thing or person deviating from the common rule, or from common forms.
Example Sentences:
(1) The first concerns precursor cells that give rise to lambda-bearing NP-specific antibodies with heteroclitic fine specificity.
(2) The data suggest that the humoral response to different epitopes of a protein antigen during the maturation of the immune response is a stochastic process leading to transient humoral immunodominance, enhancing Ab populations and heterocliticity, depending upon individual characteristics, either in outbred or inbred populations.
(3) The goal of these experiments has been to capitalize on the functionally distinct responses of heteroclitic CTL to cross-reactive Ag to explore the role of Ag in regulating CTL proliferation and lytic function.
(4) It is predicted that a combination of solid-phase competition assay with high epitope density and direct binding assay with low epitope density would result in optimal detection of heteroclitic antibodies and small differences in antibody affinity for cross-reactive antigens.
(5) By contrast, the heteroclitic Abs to eGH developed by hypopituitary patients therapeutically injected with human growth hormone failed to react with any eGH-derived fragment.
(6) m ABs 8 to 14 and 16 to 20 demonstrated heteroclitic behavior, that is, they bound CTT IIIa better than the immunogen CTT III.
(7) One assay method failed to detect heteroclitic activity of 1 antibody which was clearly evident in the other 3 assays.
(8) Moreover, some anti-BP mAbs and anti-Cop 1 mAbs reacted in a heteroclitic manner and favored the cross-reactive antigen over the immunogen.
(9) However, immunization with the heterologous peptide resulted in a response strictly directed to rat CII and the immunogen while immunization with the autologous peptide elicited T cells which reacted in a heteroclitic fashion, with a stronger response to the heterologous peptide than to the autologous peptide, and did respond to rat CII but not to mouse CII.
(10) Polypeptides (Lys-Ser-Glu)n induced cross-reacting or heteroclitic antibodies.
(11) Monoclonal and anti-dinitrophenyl and anti-trinitrophenyl IgE antibodies were used to measure heterocliticity using competitive inhibition assays with homologous and heterologous haptens.
(12) To our knowledge, this is the first description of a T cell clone that is specific for a class I antigen and cross-reacts heteroclitically with a class II antigen.
(13) A number of antibodies showed heteroclitic binding to particular insulin variants.
(14) Med., 146 (1977) 1323-1331), by comparing the encephalitogenic guinea pig sequence to a less potent analog, had also previously observed what now would be termed a heteroclitic phenomenon at the T cell level in Lewis rats.
(15) In this report, we employ a competition assay to confirm that this alloresponse involves a groove-binding peptide, demonstrate that this peptide derives from or depends on fetal calf serum and exploit a panel of antigen-presenting cell lines--each displaying an Ak complex with a different position 69 substitution--to establish that the alloresponse is not just a heteroclitic response to ribonuclease, itself.
(16) The results indicated temporal and individual variations in the titers of each class of Ab as well as the existence of enhancer and heteroclitic Ab.
(17) Products of both genes had an exotic (heteroclitic) fine-specificity.
(18) Although most of the animals showed cross-reacting Ab, two out of 12 mice, chronically injected, developed heteroclitic Ab.
(19) Heterocliticity towards non-human GH was also detected.
(20) Some of the antibodies could be inhibited to a greater degree with the cross-reacting haptens than with the haptens homologous to the immunizing antigen, therefore these antibodies were heteroclitic.