(n.) Want or absence of something necessary for completeness or perfection; deficiency; -- opposed to superfluity.
(n.) Failing; fault; imperfection, whether physical or moral; blemish; as, a defect in the ear or eye; a defect in timber or iron; a defect of memory or judgment.
(v. i.) To fail; to become deficient.
(v. t.) To injure; to damage.
Example Sentences:
(1) We have cloned the phr gene that encodes DNA photolyase from Salmonella typhimurium by in vivo complementation of Escherichia coli phr gene defect.
(2) Cor triatriatum (CT) is a rare congenital defect, surgically correctable, and sometimes difficult to diagnose by cardiac catheterization.
(3) Sixteen patients (27%) manifested anomalies of the urinary tract: 12 had markedly altered kidneys, 8 of which were unilateral and ipsilateral to the diaphragmatic defect.
(4) Furthermore echography revealed a collateral subperiosteal edema and a moderate thickening of extraocular muscles and bone periostitis, a massive swelling of muscles and bone defects in subperiosteal abscesses as well as encapsulated abscesses of the orbit and a concomitant retrobulbar neuritis in orbital cellulitis.
(5) Seven males have been observed carrying both inherited tritan and red-green defects.
(6) Mechanisms by which a defect in the synthesis of dolichol-oligosaccharides might alter the degree of beta-1,6 branching in N-linked carbohydrates are discussed.
(7) Both Types I and II collagen are important constituents of the affected tissues, and thus defective collagens are reasonable candidates for the primary abnormality in adolescent idiopathic scoliosis (AIS).
(8) Ventricular septal defect types were perimembranous (six), malalignment (seven), supracristal (three), midmuscular (one), and inlet (one).
(9) Defects of several membrane proteins were found with sodium dodecyl sulfate--polyacrylamide gel electrophoresis.
(10) After early repair of congenital cardiovascular defects, such as coarctation of the aorta, late stenosis may become a problem.
(11) The association of these defects of teeth and bone was found to be transmitted as an autosomal dominant trait over four generations.
(12) They presented their clinical observations on 4 brothers from the 'G Family' who shared a constellation of findings with a generalised tendency to midline defects.
(13) Distant ischemia was distinguished from peri-infarctional ischemia by the presence of transient thallium defects in, or slow thallium washout from myocardium not supplied by the infarct-related coronary artery.
(14) A distally based posterior tibial artery adipofascial flap with skin graft was used for the reconstruction of soft tissue defects over the Achilles tendon in three cases and over the heel in three cases.
(15) In the case with a more distally situated VSD, the bundle branches skirted the anterior and distal walls of the defect.
(16) Both models showed the expected wound-healing defects of the diabetic rats.
(17) Intercistronic complementation of these mutants with pm1493 and dl121, two SV40 mutants that are defective in agnoprotein but encode wild-type T antigen, results in an increased synthesis of agnoprotein in the infected cells.
(18) Cells defective in gpa2 fail to produce cAMP in response to glucose stimulation.
(20) This paper reports on observations of five families suffering from distinct thrombophilia due to a protein C defect.
Flawed
Definition:
(imp. & p. p.) of Flaw
Example Sentences:
(1) However, each of the studies had numerous methodological flaws which biased their results against finding a relationship: either their outcome measures had questionable validity, their research designs were inappropriate, or the statistical analyses were poorly conceived.
(2) Its experiments are so hopelessly flawed that the results are meaningless."
(3) Clute and Harrison took a scalpel to the flaws of the science fiction we loved, and we loved them for it.
(4) I can still see flaws in what I'm doing, but I think I delivered.
(5) In an interview with the Guardian, James Hansen, the world's pre-eminent climate scientist, said any agreement likely to emerge from the negotiations would be so deeply flawed that it would be better to start again from scratch.
(6) We conclude that individual case review can be severely flawed and therefore should not be used to measure institutional quality of patient care.
(7) The power of the landed elite is often cited as a major structural flaw in Pakistani politics – an imbalance that hinders education, social equality and good governance (there is no agricultural tax in Pakistan).
(8) The council offered him a tea urn | Frances Ryan Read more Government attempts to decrease the disproportionately high levels of unemployment among disabled people have had little impact, the report notes, while notorious “fit-for-work” tests were riven with flaws.
(9) Michael Brune, executive director of the Sierra Club, said he was "outraged" by what he described as the administration's "deeply flawed analysis and what can only be interpreted as lip service to one of the greatest threats to our children's future: climate disruption".
(10) What the film does, though, is use these incidents to build an idiosyncratic but insightful picture of Lawrence, played indelibly by Peter O'Toole in his debut role: a complicated, egomaniacal and physically masochistic man, at once god-like and all too flawed, with a tenuous grip both on reality and on sanity.
(11) fbi justified homicide chart Academics and specialists have long been aware of flaws in the FBI numbers, which are based on voluntary submissions by local law enforcement agencies of paperwork known as supplementary homicide reports.
(12) The system was "flawed" and the rules were "vague".
(13) Most of the 138 studies contained serious flaws in research design, such as lack of control subjects, unspecified manner of data collection, and absence of diagnostic criteria.
(14) Poor crossing undermined Liverpool in the first leg, Klopp had claimed, but the flaw was remedied quickly in the return.
(15) A variety of quality tests, of biomechanical screws, are used, before performing the operations, that flaws may be detected.
(16) The sugar tax was greeted with hostility by the industry and Wright argues that the levy, introduced by the chancellor in the budget , will be undermined by flawed analysis of its impact.
(17) Flaws in the design, execution and analysis of randomized clinical trials have been eliminated gradually over the past 35 years.
(18) A report released on Wednesday said Prevent was badly flawed , potentially counterproductive and risked trampling on the basic rights of young Muslims.
(19) A flawed heroine of the anti-apartheid struggle, she is unlikely to keep a low profile in the coming days or to bite her lip if she believes Mandela's memory is being betrayed.
(20) Considerable scholarly exertion has gone into describing the flaws in each count.