(n.) Want or absence of something necessary for completeness or perfection; deficiency; -- opposed to superfluity.
(n.) Failing; fault; imperfection, whether physical or moral; blemish; as, a defect in the ear or eye; a defect in timber or iron; a defect of memory or judgment.
(v. i.) To fail; to become deficient.
(v. t.) To injure; to damage.
Example Sentences:
(1) We have cloned the phr gene that encodes DNA photolyase from Salmonella typhimurium by in vivo complementation of Escherichia coli phr gene defect.
(2) Cor triatriatum (CT) is a rare congenital defect, surgically correctable, and sometimes difficult to diagnose by cardiac catheterization.
(3) Sixteen patients (27%) manifested anomalies of the urinary tract: 12 had markedly altered kidneys, 8 of which were unilateral and ipsilateral to the diaphragmatic defect.
(4) Furthermore echography revealed a collateral subperiosteal edema and a moderate thickening of extraocular muscles and bone periostitis, a massive swelling of muscles and bone defects in subperiosteal abscesses as well as encapsulated abscesses of the orbit and a concomitant retrobulbar neuritis in orbital cellulitis.
(5) Seven males have been observed carrying both inherited tritan and red-green defects.
(6) Mechanisms by which a defect in the synthesis of dolichol-oligosaccharides might alter the degree of beta-1,6 branching in N-linked carbohydrates are discussed.
(7) Both Types I and II collagen are important constituents of the affected tissues, and thus defective collagens are reasonable candidates for the primary abnormality in adolescent idiopathic scoliosis (AIS).
(8) Ventricular septal defect types were perimembranous (six), malalignment (seven), supracristal (three), midmuscular (one), and inlet (one).
(9) Defects of several membrane proteins were found with sodium dodecyl sulfate--polyacrylamide gel electrophoresis.
(10) After early repair of congenital cardiovascular defects, such as coarctation of the aorta, late stenosis may become a problem.
(11) The association of these defects of teeth and bone was found to be transmitted as an autosomal dominant trait over four generations.
(12) They presented their clinical observations on 4 brothers from the 'G Family' who shared a constellation of findings with a generalised tendency to midline defects.
(13) Distant ischemia was distinguished from peri-infarctional ischemia by the presence of transient thallium defects in, or slow thallium washout from myocardium not supplied by the infarct-related coronary artery.
(14) A distally based posterior tibial artery adipofascial flap with skin graft was used for the reconstruction of soft tissue defects over the Achilles tendon in three cases and over the heel in three cases.
(15) In the case with a more distally situated VSD, the bundle branches skirted the anterior and distal walls of the defect.
(16) Both models showed the expected wound-healing defects of the diabetic rats.
(17) Intercistronic complementation of these mutants with pm1493 and dl121, two SV40 mutants that are defective in agnoprotein but encode wild-type T antigen, results in an increased synthesis of agnoprotein in the infected cells.
(18) Cells defective in gpa2 fail to produce cAMP in response to glucose stimulation.
(20) This paper reports on observations of five families suffering from distinct thrombophilia due to a protein C defect.
Idiosyncrasy
Definition:
(n.) A peculiarity of physical or mental constitution or temperament; a characteristic belonging to, and distinguishing, an individual; characteristic susceptibility; idiocrasy; eccentricity.
Example Sentences:
(1) Since 1887, winter green is claimed to have caused dermatitis and to have been responsible for "idiosyncrasy".
(2) Until now it has not been possible to define the enzymatic abnormality which could explain this metabolic type of idiosyncrasy.
(3) Factors limiting the interpretability and generalizability of these findings are discussed with particular reference to sample size and idiosyncrasies.
(4) The mechanisms involve toxicity, idiosyncrasy, allergy, or a combination.
(5) Cincophen induces hepatic necrosis through a hypersensitivity or metabolic idiosyncrasy mechanism with histologic abnormalities similar to those due to isoniazid, anticonvulsants, halothane and methyldopa.
(6) There was distinct host idiosyncrasy in the pattern of estimated counts of these five types.
(7) This method involves building a face with clay or other suitable material on to a skull or its cast, taking into account appropriate facial thickness measurements together with information provided by anthropologists such as approximate age, sex, race and other individual idiosyncrasies.
(8) To test whether this diversity was a geographic idiosyncrasy, we analyzed 25 cervical biopsy specimens from Brazil.
(9) This is further complicated by the added impact of pharmacokinetic idiosyncrasies displayed by children, coupled with the routine pitfalls of therapeutic drug monitoring seen in any patient population.
(10) In particular, caries diagnosis and restorative treatment planning are subject to considerable idiosyncrasies.
(11) In order to identify generalities and detect idiosyncrasies, analyses were carried out using RNase P RNAs from three phylogenetically diverse organisms: Bacillus subtilis, Chromatium vinosum and Escherichia coli.
(12) Review: Amazon’s Fire Phone offers new gimmicks, old platform growing pains - Ars Technica Past tablet success isn't enough to guarantee a win for Amazon in the high-end smartphone game for Andrew Cunningham for Ars Technica: The problem is that even if all of your media lives in Amazon's cloud, phones running iOS or Google-approved Android can access all of it without the third-party app gap or FireOS' idiosyncrasies (the exception is Instant Video on Android, though rumour has it that Amazon will be releasing that app soon).
(13) It is curious that no antiarrhythmic drug seems to be statistically less exposed to this type of complication which may result from phenomena of toxicity or idiosyncrasy.
(14) I write a personal blog and it often features my sons: their weird enthusiasms, their idiosyncrasies, their repeated requests that I look at a picture of a man selling advertising space on his neck goitre in the Ripley's Believe it or Not!
(15) South Africa’s idiosyncrasies, from party politics to the high crime rate, provided regular material.
(16) His descriptions – of battlefields or mushroom-picking or meals – are full of exactly the right amount of idiosyncrasy and detail.
(17) However, since the hepatotoxicity appears to involve an element of idiosyncrasy, the primary defect in some cases may be an inherited or acquired deficiency in the drug's beta-oxidation.
(18) Since inhibition of cyclo-oxygenase precipitates asthmatic attacks in patients with aspirin idiosyncrasy, we have evaluated the effects of pharmacological inhibition of the next enzyme in arachidonic acid cascade, i.e., thromboxane synthetase.
(19) Lithium discontinuation produced a significant increase in associational productivity and a demonstrable increase in associative idiosyncrasy, and restoration of lithium dose significantly reversed both effects.
(20) The variability among qualitative judgments of odors which makes it difficult to construct reliable classifications may depend on cultural or personal idiosyncrasies.