What's the difference between defect and impurity?

Defect


Definition:

  • (n.) Want or absence of something necessary for completeness or perfection; deficiency; -- opposed to superfluity.
  • (n.) Failing; fault; imperfection, whether physical or moral; blemish; as, a defect in the ear or eye; a defect in timber or iron; a defect of memory or judgment.
  • (v. i.) To fail; to become deficient.
  • (v. t.) To injure; to damage.

Example Sentences:

  • (1) We have cloned the phr gene that encodes DNA photolyase from Salmonella typhimurium by in vivo complementation of Escherichia coli phr gene defect.
  • (2) Cor triatriatum (CT) is a rare congenital defect, surgically correctable, and sometimes difficult to diagnose by cardiac catheterization.
  • (3) Sixteen patients (27%) manifested anomalies of the urinary tract: 12 had markedly altered kidneys, 8 of which were unilateral and ipsilateral to the diaphragmatic defect.
  • (4) Furthermore echography revealed a collateral subperiosteal edema and a moderate thickening of extraocular muscles and bone periostitis, a massive swelling of muscles and bone defects in subperiosteal abscesses as well as encapsulated abscesses of the orbit and a concomitant retrobulbar neuritis in orbital cellulitis.
  • (5) Seven males have been observed carrying both inherited tritan and red-green defects.
  • (6) Mechanisms by which a defect in the synthesis of dolichol-oligosaccharides might alter the degree of beta-1,6 branching in N-linked carbohydrates are discussed.
  • (7) Both Types I and II collagen are important constituents of the affected tissues, and thus defective collagens are reasonable candidates for the primary abnormality in adolescent idiopathic scoliosis (AIS).
  • (8) Ventricular septal defect types were perimembranous (six), malalignment (seven), supracristal (three), midmuscular (one), and inlet (one).
  • (9) Defects of several membrane proteins were found with sodium dodecyl sulfate--polyacrylamide gel electrophoresis.
  • (10) After early repair of congenital cardiovascular defects, such as coarctation of the aorta, late stenosis may become a problem.
  • (11) The association of these defects of teeth and bone was found to be transmitted as an autosomal dominant trait over four generations.
  • (12) They presented their clinical observations on 4 brothers from the 'G Family' who shared a constellation of findings with a generalised tendency to midline defects.
  • (13) Distant ischemia was distinguished from peri-infarctional ischemia by the presence of transient thallium defects in, or slow thallium washout from myocardium not supplied by the infarct-related coronary artery.
  • (14) A distally based posterior tibial artery adipofascial flap with skin graft was used for the reconstruction of soft tissue defects over the Achilles tendon in three cases and over the heel in three cases.
  • (15) In the case with a more distally situated VSD, the bundle branches skirted the anterior and distal walls of the defect.
  • (16) Both models showed the expected wound-healing defects of the diabetic rats.
  • (17) Intercistronic complementation of these mutants with pm1493 and dl121, two SV40 mutants that are defective in agnoprotein but encode wild-type T antigen, results in an increased synthesis of agnoprotein in the infected cells.
  • (18) Cells defective in gpa2 fail to produce cAMP in response to glucose stimulation.
  • (19) Moloney murine sarcoma virus ts110 possesses a thermosensitive splicing defect.
  • (20) This paper reports on observations of five families suffering from distinct thrombophilia due to a protein C defect.

Impurity


Definition:

  • (n.) The condition or quality of being impure in any sense; defilement; foulness; adulteration.
  • (n.) That which is, or which renders anything, impure; foul matter, action, language, etc.; a foreign ingredient.
  • (n.) Want of ceremonial purity; defilement.

Example Sentences:

  • (1) Two other impurities are pyrene derivatives but their acyl chains probably are not decanoic acid.
  • (2) No impurities in the technical grade ether influenced the responses.
  • (3) The UV and IR absorption spectra of compounds present in the eluate were compared with those of model compounds that were assumed to exist in the gel as impurities after the polymerization (monomers and oligomers of hydroxyethyl methacrylate, decomposition products of initiators).
  • (4) Chloramphenicol, dinitrophenol, and impurities present in some brands of agar all appear to inhibit the growth-medium-dependent branch of excision-repair.
  • (5) The combined results describe the depth of segregation of DMS blocks in Avcothane, the presence of DMS within the topmost 20 A in Biomer, and similar impurities in the model polymers.
  • (6) An impure sample of PLC inhibited sperm penetration, while a more purified preparation did not.
  • (7) A liquid chromatographic (LC) method was adapted for the determination of epinephrine and related impurities in intravenous and cardiac injections; ultraviolet (UV) and electrochemical detectors (EC) were used in series.
  • (8) The determination of potency or shelf life, impurity limit testing, and study of reaction mechanisms are considered as different aspects of drug stability.
  • (9) Isolated cytochrome c oxidase was fractionated by native-gel electrophoresis in Triton X-100, and a preparation of enzyme almost completely free of the usual impurities was recovered.
  • (10) Although these are worst case calculations, a consistent approach should be reconsidered to limit the additional effective dose equivalent from impurities to e.g.
  • (11) As little as 50 nmol of a protein may be quantified and an impurity peak of molecular weight ca.
  • (12) Not all impurities were found in every lot of drug investigated, and none of the impurities exceeded a concentration of 1% of the meperidine present.
  • (13) Skin impurities and fatty hair associated with acne were side effects in 22.5% of 378 patients during the first evaluation and in 10.8% of 369 patients at the second evaluation.
  • (14) The organic solvent soluble impurities exhibited strong mutagenic activity for TA98 and slight activity for TA100.
  • (15) Following this order the absorbents can be used for purification of human albumin from non-specific impurities taking into account stronger adsorption of albumin or impurities.
  • (16) Trace amounts of an impurity commonly produced in the synthesis of 1,2-distearoyl-3-sn-phosphatidylcholine, 1,3-distearoyl-2-sn-phosphatidylcholine, are found to dramatically reduce the rate of loss of small vesicles at 21 degrees C.
  • (17) It is shown on the basis of calculations of energy sublevels of the hyperfine structure that the effect of the geomagnetic field upon the impurity atoms in the volume of living cells should be considered in relation to the value of geomagnetic field induction pulses delta B.
  • (18) Contamination of cells by impurity atoms that may leach from electrodes was measured by atomic-absorption spectrophotometry and found to be negligible.
  • (19) Results presented here indicate that N-nitroso compound impurities are absent from the majority of the products tested.
  • (20) Eight of the proteins (L9, L11, L13, L21, L22, L35', L37 and L39) had no detectable contamination; the impurities in the others were no greater than 9%.