(v. t.) To spoil the form of; to mar in form; to misshape; to disfigure.
(v. t.) To render displeasing; to deprive of comeliness, grace, or perfection; to dishonor.
(a.) Deformed; misshapen; shapeless; horrid.
Example Sentences:
(1) Gross deformity, point tenderness and decrease in supination and pronation movements of the forearm were the best predictors of bony injury.
(2) Rigidly fixing the pubic symphysis stiffened the model and resulted in principal stress patterns that did not reflect trabecular density or orientations as well as those of the deformable pubic symphysis model.
(3) Cloacal exstrophy, centered on the maldevelopment of the primitive streak mesoderm and cloacal membrane, results in bladder and intestinal exstrophy, omphalocele, gender confusion, and hindgut deformity.
(4) In a family with hereditary elliptocytosis and an abnormality in spectrin self-association, the membranes had decreased deformability and stability.
(5) The most important causal factor, well illustrated by pressure studies, was the presence of a dynamic or static deformity leading to local areas of peak pressure on insensitive skin.
(6) Predominantly observed defects included neural crest cells in ectopic locations, both within and external to the neural tube, and mildly deformed neural tubes containing some dissociating cells.
(7) Emergency CT showed evidence of pericardial effusion suggesting hemopericardium, enlargement of the ascending aorta and a peripheral semilunar filling defect which caused a slight deformation of the true channel.
(8) Changes in the determinants of blood viscosity (packed cell volume, plasma viscosity, red cell aggregation, and red cell deformability) were studied on day 1 and day 5.
(9) A model for left ventricular diastolic mechanics is formulated that takes into account noneligible wall thickness, incompressibility, finite deformation, nonlinear elastic effects, and the known fiber architecture of the ventricular wall.
(10) As a consequence of deformation from spherical-to-cylindrical shape in the microvasculature, demands for increased surface membrane area leads to increases in surface membrane tension above critical levels for rupture, and the cancer cells are rapidly and lethally damaged.
(11) Within the restriction provided by surface area and volume, the intrinsic properties of the membrane and cytoplasm determine the deformability characteristics of the red cell.
(12) In 12 patients with lower macrognathia we have applied a technique allowing to prevent the postsurgical recidives of the jaw deformation.
(13) Filtration of red blood cells through agarose gels (Sephadex, Sepharose, and Superose) was used to assess red cell deformability and simultaneously obtain fractions of red cells with different properties.
(14) Such deformities may be the only future indication for the use of this operation as these knees do not do well when treated by tibial osteotomy.
(15) Richard now is presented, albeit somewhat inconsistently, as evil in response to social ostracism because of his ugly deformities.
(16) Calcium-dependent ATPase, adenylate cyclase and phosphorylation of erythrocyte membrane proteins have been found abnormal in various conditions: hereditary spherocytosis, sickle-cell anemia, progressive muscular dystrophies, all of these disorders being associated with a decreased deformability of the erythrocyte.
(17) Thus many athletes sustain dental-related injuries resulting in deformity and discomfort which may persist throughout their lives.
(18) Type II had the anastomosis too high on the gastric pouch, type III was due to an obstructing marginal ulcer, and type IV had a pouchlike deformity develop in the upper jejunum at the anastomosis that gradually compressed the outflow tract.
(19) This procedure was done in 4 patients and corrected the deformity efficiently, allowing for satisfactory sexual function.
(20) Angiography was performed on 74 hands of 70 patients in this series, and attempts were made to correlate these with the types of the deformities.
Misshapen
Definition:
(a.) Having a bad or ugly form.
Example Sentences:
(1) Capote clearly identified with this "chunky, misshapen child-man".
(2) These cells included many abnormal forms such as giant cells and misshapen cells.
(3) A sixfold increase (P less than 0.0001) in hepatic iron and a fivefold increase in lysosomal iron (P less than 0.01) was observed after iron loading; as a result, hepatocyte lysosomes became enlarged and misshapen.
(4) Findings common to both and typical for this chromosome aberration include a narrow protruding forehead, hypertelorism, non-horizontal position of the eyes, ptosis, strabismus, broad root, and short upturned tip of thenose, carp mouth, receding chin, misshapen ears, simian creases, and severe mental retardation.
(5) Because major components of the craniofacial complex were generally present, although misshapen, changes in the atelencephalic skull seem to be deformations rather than malformations.
(6) Walking around Forgemasters it is impossible not to be stirred: great misshapen lumps of scrap steel, red heat shining through furnace doors, huge presses, and a machining hall where the black crust is cut from immense forgings to produce shiny precision-engineered parts.
(7) It was "misshapen" by torture, bore signs of beatings, and had a fractured skull, he told the committee.
(8) The overall histological picture consisted of a fairly repetitive pattern dominated by an exuberant and diffuse hyperplasia of frequently misshapen and poorly outlined follicles, associated with a striking proliferation of capillary vessels and a very consistent amount of plasma cells both extending in the follicular and interfollicular areas.
(9) The gross anomalies involved the smaller size of the club-foot talus and the increased medial deviation of a stunted, misshapen head and neck region.
(10) The first and second pairs of valvulae were often misshapen and reduced in sclerotization and length, or even fused with the third valvulae.
(11) A newborn female is described who exhibited a characteristic facial dysmorphology including deep-set eyes, broad nasal bridge, small mouth, high-arched and narrow palate, severly receding mandible and misshapen ears; constant flexion of the proximal interphalangeal joints, and short distal phalanges and nails of fingers; a congenital heart defect; marked muscular hypotonia, motor and growth retardation.
(12) Although differentiated, most tissues are morphologically misshapen.
(13) The abnormalities fell into two main classes: misshapen or bulging eggs and eggs coated with a superficial layer of amorphous calcium, variously termed dusted, white banded, chalky or pink eggs.
(14) Newly reverted cells were misshapen and osmotically sensitive.
(15) Their outer segments were at first short, wide, and misshapen; only as they grew longer and narrower did they become straight and properly aligned.
(16) Admittedly he does now resemble a boiled sweet that was lost down the back of the sofa only to be unearthed months later, fuzzy and misshapen.
(17) The increased GalTase activity on t-bearing spermatids is not due to decreased hydrolysis of the GalTase substrates, and is appropriately localized over the acrosomal region, even on misshapen sperm heads occasionally seen in t-sperm populations.
(18) Flickerman functions as the grotesque face of the elite, with bright blue hair and a face misshapen by frequent visits to the plastic surgeon.
(19) ); eye (lens misshapen or severely thinned, optic cup incompletely invaginated); diencephalon (epiphysis bifurcated or off-center, supernumerary outgrowths); cardiovascular structures (atrium and major blood vessels enlarged); and tailbud (curled into hindgut: ourentery).
(20) Significant dental findings were severe enamel hypoplasia, conical and misshapen teeth, hypodontia, and impactions.