(v. t.) To spoil the form of; to mar in form; to misshape; to disfigure.
(v. t.) To render displeasing; to deprive of comeliness, grace, or perfection; to dishonor.
(a.) Deformed; misshapen; shapeless; horrid.
Example Sentences:
(1) Gross deformity, point tenderness and decrease in supination and pronation movements of the forearm were the best predictors of bony injury.
(2) Rigidly fixing the pubic symphysis stiffened the model and resulted in principal stress patterns that did not reflect trabecular density or orientations as well as those of the deformable pubic symphysis model.
(3) Cloacal exstrophy, centered on the maldevelopment of the primitive streak mesoderm and cloacal membrane, results in bladder and intestinal exstrophy, omphalocele, gender confusion, and hindgut deformity.
(4) In a family with hereditary elliptocytosis and an abnormality in spectrin self-association, the membranes had decreased deformability and stability.
(5) The most important causal factor, well illustrated by pressure studies, was the presence of a dynamic or static deformity leading to local areas of peak pressure on insensitive skin.
(6) Predominantly observed defects included neural crest cells in ectopic locations, both within and external to the neural tube, and mildly deformed neural tubes containing some dissociating cells.
(7) Emergency CT showed evidence of pericardial effusion suggesting hemopericardium, enlargement of the ascending aorta and a peripheral semilunar filling defect which caused a slight deformation of the true channel.
(8) Changes in the determinants of blood viscosity (packed cell volume, plasma viscosity, red cell aggregation, and red cell deformability) were studied on day 1 and day 5.
(9) A model for left ventricular diastolic mechanics is formulated that takes into account noneligible wall thickness, incompressibility, finite deformation, nonlinear elastic effects, and the known fiber architecture of the ventricular wall.
(10) As a consequence of deformation from spherical-to-cylindrical shape in the microvasculature, demands for increased surface membrane area leads to increases in surface membrane tension above critical levels for rupture, and the cancer cells are rapidly and lethally damaged.
(11) Within the restriction provided by surface area and volume, the intrinsic properties of the membrane and cytoplasm determine the deformability characteristics of the red cell.
(12) In 12 patients with lower macrognathia we have applied a technique allowing to prevent the postsurgical recidives of the jaw deformation.
(13) Filtration of red blood cells through agarose gels (Sephadex, Sepharose, and Superose) was used to assess red cell deformability and simultaneously obtain fractions of red cells with different properties.
(14) Such deformities may be the only future indication for the use of this operation as these knees do not do well when treated by tibial osteotomy.
(15) Richard now is presented, albeit somewhat inconsistently, as evil in response to social ostracism because of his ugly deformities.
(16) Calcium-dependent ATPase, adenylate cyclase and phosphorylation of erythrocyte membrane proteins have been found abnormal in various conditions: hereditary spherocytosis, sickle-cell anemia, progressive muscular dystrophies, all of these disorders being associated with a decreased deformability of the erythrocyte.
(17) Thus many athletes sustain dental-related injuries resulting in deformity and discomfort which may persist throughout their lives.
(18) Type II had the anastomosis too high on the gastric pouch, type III was due to an obstructing marginal ulcer, and type IV had a pouchlike deformity develop in the upper jejunum at the anastomosis that gradually compressed the outflow tract.
(19) This procedure was done in 4 patients and corrected the deformity efficiently, allowing for satisfactory sexual function.
(20) Angiography was performed on 74 hands of 70 patients in this series, and attempts were made to correlate these with the types of the deformities.
Rugged
Definition:
(n.) Full of asperities on the surface; broken into sharp or irregular points, or otherwise uneven; not smooth; rough; as, a rugged mountain; a rugged road.
(n.) Not neat or regular; uneven.
(n.) Rough with bristles or hair; shaggy.
(n.) Harsh; hard; crabbed; austere; -- said of temper, character, and the like, or of persons.
(n.) Stormy; turbulent; tempestuous; rude.
(n.) Rough to the ear; harsh; grating; -- said of sound, style, and the like.
(n.) Sour; surly; frowning; wrinkled; -- said of looks, etc.
(n.) Violent; rude; boisterrous; -- said of conduct, manners, etc.
(n.) Vigorous; robust; hardy; -- said of health, physique, etc.
Example Sentences:
(1) The hosts had resisted through the early stages, emulating their rugged first-half displays against Manchester United and Arsenal here this season, and even mustered a flurry of half-chances just before the interval to offer a reminder they might glean greater reward thereafter.
(2) Steps wind down a rugged rock face to a bedroom, while light floods in from round skylights in the domed ceiling above.
(3) The Turner prize-winning artist has turned his sights on the survivalist and his exceptionally rugged version of masculinity, arguing that it isn’t fit for the 21st century.
(4) Many survivors use it to get the accommodations needed to stay in school, while others used it to hold their institutions accountable for sweeping sexual assault under the rug.” More than two dozen states are suing the Obama administration over its guidance on transgender students in an effort that is overwhelmingly led by Republican secretaries of state.
(5) As the president of Russia's Kalmykia republic from 1993 to 2010, Ilyumzhinov undoubtedly has close ties to the Kremlin, and a woven rug featuring Putin's face hangs in his office.
(6) Also, a wildfire in a rugged area near the Canadian border chased hundreds of people from their homes and burned 10 to 12 structures, and a blaze north-east of Colville scorched almost five square miles and forced evacuations at campgrounds in the area.
(7) Allergenic proteins were extracted from one silk batch that was imported to be used as filling material for bed mattresses and rugs.
(8) And reporting by the Observer reveals the extent to which al-Qaida has integrated itself with powerful tribes that control large swaths of Yemen's rugged east and parts of its south.
(9) FIVE MORE FRENCH COASTAL GEMS Marseille grotto Facebook Twitter Pinterest Photograph: Alamy A 40-minute walk from Marseille’s Luminy university campus, Calanque de Sugiton, the most picturesque of the city’s rugged, limestone coves has blue-green waters, twisted pine trees and a narrow island-rock to swim out to known as Le Torpilleur.
(10) Laminin and its E1-4 and E8 fragments are able to activate the ecto-5'-nucleotidase activity of both BCS-TC2 and Rugli cells.
(11) Pictures of the young Depardieu in a good light suggest a rugged, brooding, if not classically good-looking man with a squared chin and mop of blonde hair.
(12) In the presence of glucose oxidase and trien this polymer forms rugged, cross-linked, electroactive films on the surface of electrodes, thereby eliminating the requirement for a membrane for containing the enzyme and redox couple.
(13) The tone was set in the second minute when Ben Westwood, Warrington's notoriously rugged forward, left the Wigan stand-off Blake Green on the ground needing lengthy treatment.
(14) The simple design and rugged construction permit the incorporation of the apparatus into many manual or personal computer controlled oxygen consumption systems.
(15) Both offer lodges and campsites, but keep in mind that only a very small fraction of these remote and rugged parks are accessible by road.
(16) "When a similar report was released in 2009, the Administration largely swept it under the rug.
(17) La Posada has undergone a $12m renovation, transforming it into a magical place with handmade Mexican tin and tile mirrors, six-foot cast iron tubs, hand woven Zapotec rugs, and hand-painted furniture and tile murals.
(18) These assays have proven to be accurate, precise, reproducible, and rugged during clinical sample analyses.
(19) And cutting support now would take demand out of the economy, pull the rug from under the recovery, and delay our return to sustained growth.
(20) Chelsea had laboured at times without him in that first period, Begovic denying them reward from an urgent opening and Stoke rugged and organised until self-destructing with half-time in sight.