(a.) Unnatural or distorted in form; having a deformity; misshapen; disfigured; as, a deformed person; a deformed head.
Example Sentences:
(1) Gross deformity, point tenderness and decrease in supination and pronation movements of the forearm were the best predictors of bony injury.
(2) Rigidly fixing the pubic symphysis stiffened the model and resulted in principal stress patterns that did not reflect trabecular density or orientations as well as those of the deformable pubic symphysis model.
(3) Cloacal exstrophy, centered on the maldevelopment of the primitive streak mesoderm and cloacal membrane, results in bladder and intestinal exstrophy, omphalocele, gender confusion, and hindgut deformity.
(4) In a family with hereditary elliptocytosis and an abnormality in spectrin self-association, the membranes had decreased deformability and stability.
(5) The most important causal factor, well illustrated by pressure studies, was the presence of a dynamic or static deformity leading to local areas of peak pressure on insensitive skin.
(6) Predominantly observed defects included neural crest cells in ectopic locations, both within and external to the neural tube, and mildly deformed neural tubes containing some dissociating cells.
(7) Emergency CT showed evidence of pericardial effusion suggesting hemopericardium, enlargement of the ascending aorta and a peripheral semilunar filling defect which caused a slight deformation of the true channel.
(8) Changes in the determinants of blood viscosity (packed cell volume, plasma viscosity, red cell aggregation, and red cell deformability) were studied on day 1 and day 5.
(9) A model for left ventricular diastolic mechanics is formulated that takes into account noneligible wall thickness, incompressibility, finite deformation, nonlinear elastic effects, and the known fiber architecture of the ventricular wall.
(10) As a consequence of deformation from spherical-to-cylindrical shape in the microvasculature, demands for increased surface membrane area leads to increases in surface membrane tension above critical levels for rupture, and the cancer cells are rapidly and lethally damaged.
(11) Within the restriction provided by surface area and volume, the intrinsic properties of the membrane and cytoplasm determine the deformability characteristics of the red cell.
(12) In 12 patients with lower macrognathia we have applied a technique allowing to prevent the postsurgical recidives of the jaw deformation.
(13) Filtration of red blood cells through agarose gels (Sephadex, Sepharose, and Superose) was used to assess red cell deformability and simultaneously obtain fractions of red cells with different properties.
(14) Such deformities may be the only future indication for the use of this operation as these knees do not do well when treated by tibial osteotomy.
(15) Richard now is presented, albeit somewhat inconsistently, as evil in response to social ostracism because of his ugly deformities.
(16) Calcium-dependent ATPase, adenylate cyclase and phosphorylation of erythrocyte membrane proteins have been found abnormal in various conditions: hereditary spherocytosis, sickle-cell anemia, progressive muscular dystrophies, all of these disorders being associated with a decreased deformability of the erythrocyte.
(17) Thus many athletes sustain dental-related injuries resulting in deformity and discomfort which may persist throughout their lives.
(18) Type II had the anastomosis too high on the gastric pouch, type III was due to an obstructing marginal ulcer, and type IV had a pouchlike deformity develop in the upper jejunum at the anastomosis that gradually compressed the outflow tract.
(19) This procedure was done in 4 patients and corrected the deformity efficiently, allowing for satisfactory sexual function.
(20) Angiography was performed on 74 hands of 70 patients in this series, and attempts were made to correlate these with the types of the deformities.
Teratology
Definition:
(n.) That branch of biological science which treats of monstrosities, malformations, or deviations from the normal type of structure, either in plants or animals.
(n.) Affectation of sublimity; bombast.
Example Sentences:
(1) The importance of precocious development for planning teratological studies is emphasized.
(2) Unlike previous studies with 13-cis-retinoic acid during the pre- and early organogenic stages of development (Hummler et al., Teratology 42:263-272, 1990), no thymic hypo- or aplasia or heart anomalies were observed, which may be attributable to the slightly longer 13-cis retinoic acid treatment period, i.e., GD 10-27.
(3) It seems likely that diaphragmatic hernia is a non-specific consequence of several teratological processes.
(4) The principles of teratology are described, and animal models for research in abnormal ocular development and clinical studies of human teratogens are surveyed.
(5) Functional teratology is quite a new concept in neuroscience.
(6) Dams were killed on Day 19 and the fetuses were assessed for teratologic anomalies.
(7) On the basis of findings published in the literature, morphologic changes seen among the author's patients were classified as anthropologic and teratologic dislocations.
(8) The synthesis of these sciences into the relatively nascent science of reproductive toxicology includes teratology, pharmacology, epidemiology, and occupational and environmental health.
(9) In 1652, a chair of anatomy was created; embryology and teratology, at that time solely morphological sciences, depended on anatomy.
(10) No teratological or abortifacient effects were noted.
(11) The elaboration of the effect of retinoic acid on limb morphogenesis has prompted renewed investigation into the teratology of retinoic acid treatment, with the hope that such analysis might give insight into mechanisms of vertebrate patterning.
(12) The first generation (F0) gilts were bred after 4 months of study; some were killed for teratologic assays at 100 days of gestation (dg), and the others produced an F1 generation of offspring.
(13) The results are discussed with particular reference to the evaluation of teratologic studies on food colouring in general and the various regulation proposals from the National Food Administration.
(14) It also illustrates that selected histochemical studies may be helpful in a teratologic investigation.
(15) Subtle functional disturbances in organisms exposed while immature (behavioral teratology) may be one of the most sensitive indicators of chemical toxicity.
(16) N-Ethyl-N-nitrosourea (ENU) was administered intravenously to pregnant Wistar-albino rats on days 14--21 of gestation in order to study the teratological effects of the carcinogen on the developing brain.
(17) Concerning the applied doses no teratological effect was observed.
(18) The developmental toxicity of acetonitrile and 5 halogenated derivatives was examined with an in vivo teratology screen adapted for use in the Long-Evans rat.
(19) A wealth of literature has become available about lasting functional consequences of perinatal psychotropic drug exposure, having affected brain development in a subtle rather than gross structural way (behavioral teratology or functional neuroteratology).
(20) It is suggested that teratological investigations be carried out on the basis of a clearly formulated problem using experimental procedures suited to the biological characteristics of the test substances and of the animals.