(a.) The state of being deformed; want of proper form or symmetry; any unnatural form or shape; distortion; irregularity of shape or features; ugliness.
(a.) Anything that destroys beauty, grace, or propriety; irregularity; absurdity; gross deviation from order or the established laws of propriety; as, deformity in an edifice; deformity of character.
Example Sentences:
(1) Gross deformity, point tenderness and decrease in supination and pronation movements of the forearm were the best predictors of bony injury.
(2) Rigidly fixing the pubic symphysis stiffened the model and resulted in principal stress patterns that did not reflect trabecular density or orientations as well as those of the deformable pubic symphysis model.
(3) Cloacal exstrophy, centered on the maldevelopment of the primitive streak mesoderm and cloacal membrane, results in bladder and intestinal exstrophy, omphalocele, gender confusion, and hindgut deformity.
(4) In a family with hereditary elliptocytosis and an abnormality in spectrin self-association, the membranes had decreased deformability and stability.
(5) The most important causal factor, well illustrated by pressure studies, was the presence of a dynamic or static deformity leading to local areas of peak pressure on insensitive skin.
(6) Predominantly observed defects included neural crest cells in ectopic locations, both within and external to the neural tube, and mildly deformed neural tubes containing some dissociating cells.
(7) Emergency CT showed evidence of pericardial effusion suggesting hemopericardium, enlargement of the ascending aorta and a peripheral semilunar filling defect which caused a slight deformation of the true channel.
(8) Changes in the determinants of blood viscosity (packed cell volume, plasma viscosity, red cell aggregation, and red cell deformability) were studied on day 1 and day 5.
(9) A model for left ventricular diastolic mechanics is formulated that takes into account noneligible wall thickness, incompressibility, finite deformation, nonlinear elastic effects, and the known fiber architecture of the ventricular wall.
(10) As a consequence of deformation from spherical-to-cylindrical shape in the microvasculature, demands for increased surface membrane area leads to increases in surface membrane tension above critical levels for rupture, and the cancer cells are rapidly and lethally damaged.
(11) Within the restriction provided by surface area and volume, the intrinsic properties of the membrane and cytoplasm determine the deformability characteristics of the red cell.
(12) In 12 patients with lower macrognathia we have applied a technique allowing to prevent the postsurgical recidives of the jaw deformation.
(13) Filtration of red blood cells through agarose gels (Sephadex, Sepharose, and Superose) was used to assess red cell deformability and simultaneously obtain fractions of red cells with different properties.
(14) Such deformities may be the only future indication for the use of this operation as these knees do not do well when treated by tibial osteotomy.
(15) Richard now is presented, albeit somewhat inconsistently, as evil in response to social ostracism because of his ugly deformities.
(16) Calcium-dependent ATPase, adenylate cyclase and phosphorylation of erythrocyte membrane proteins have been found abnormal in various conditions: hereditary spherocytosis, sickle-cell anemia, progressive muscular dystrophies, all of these disorders being associated with a decreased deformability of the erythrocyte.
(17) Thus many athletes sustain dental-related injuries resulting in deformity and discomfort which may persist throughout their lives.
(18) Type II had the anastomosis too high on the gastric pouch, type III was due to an obstructing marginal ulcer, and type IV had a pouchlike deformity develop in the upper jejunum at the anastomosis that gradually compressed the outflow tract.
(19) This procedure was done in 4 patients and corrected the deformity efficiently, allowing for satisfactory sexual function.
(20) Angiography was performed on 74 hands of 70 patients in this series, and attempts were made to correlate these with the types of the deformities.
Osteoclasis
Definition:
(n.) The operation of breaking a bone in order to correct deformity.
Example Sentences:
(1) The modern corticotomy has evolved from the initial open osteotomies, which eventually proved to be traumatic to bone's osteogenic elements, and closed bone osteoclasis, which proved time consuming and difficult to control.
(2) The question of osteoblastic osteoclasis falls into this category.
(3) The distractions were performed after both open osteotomy and closed osteoclasis.
(4) The correction of angular deformities of long bones by incomplete osteotomy, followed three weeks later by manual osteoclasis, overcomes the problem of secondary displacement sometimes seen after correction by complete osteotomy and makes internal fixation unnecessary.
(5) Bone loss may be the direct result of mechanical injury, increased osteoclasis, or direct lysis of bone by various enzymes released by the interface membrane.
(6) Eight years ago, axial correction of deformities of the femora and tibiae by manual osteoclasis was carried out in a 7 year old girl in whom osteogenesis imperfecta had produced severe bowing of the long bones of the legs.
(7) In one case, a 15 degree internal rotation deformity was corrected after 5 weeks by osteoclasis and fresh elastic nailing which also healed.
(8) Ultimately, this led to the combination of an open partial subperiosteal cortical osteotomy, followed by manual osteoclasis of the remainder of the bone cortex.
(9) It is concluded that in metaphyseal bone 1,25-(OH)2D3 increased the number and synthetic activity of osteoblasts without significantly enhancing osteoclasis or osteocytic osteolysis.
(10) These findings were interpreted to suggest that PTH mobilizes bone mineral by osteoclasis and increases metabolic activity of the osteocyte-osteoblast pump.
(11) Increased osteoclasis in uremic rats was limited to diaphyseal cortical bone while metaphyseal trabeculae were relatively unaffected compared to sham-operated rats administered vitamin D. Ultrastructurally thyroid C cells were degranulated and in an active stage in both groups of rats receiving vitamin D. Urinary calcium excretion was greater in sham-operated rats given vitamin D than in uremic rats.
(12) As there was no elevation of the osteoblastic activity in knee joints with developing osteoarthrosis, it would appear that bone sclerosis associated with the disease was due to decreased osteoclasis.
(13) Modes and surgical treatment include osteoclasis and percutaneous pinning for long-bone deformities in the infant and, in the child older than two years of age, segmentation and the use of telescoping rods.
(14) An excess of bone surfaces were covered by osteoid seams, all of which showed active mineralisation, indicating a relative increase in osteoblastic activity; osteoclasis seemed to be unaffected.
(15) In rats given 5 units of 1,25-(OH)2D3, osteoclasis was markedly increased.
(16) Eight of fourteen patients elected some form of surgical revision, most commonly closed osteoclasis with restoration of femoral length, followed by the insertion of a statically locked nail.
(17) The results accord with hypotheses that (1) osteoclasis of scaffoldtype woven bone is impaired in mi mi, (2) that osteoclastic cells are derived through circulating monocytes from hematopoietic stem cells, and (3) in mi mi this defect can be overcome by a transplant of normal hemopoietic stem cells.