(a.) Having become worse than one's kind, or one's former state; having declined in worth; having lost in goodness; deteriorated; degraded; unworthy; base; low.
(v. i.) To be or grow worse than one's kind, or than one was originally; hence, to be inferior; to grow poorer, meaner, or more vicious; to decline in good qualities; to deteriorate.
(v. i.) To fall off from the normal quality or the healthy structure of its kind; to become of a lower type.
Example Sentences:
(1) Thus, our results indicate that calbindin-D28k is a useful marker for the projection system from the matrix compartment and that its expression is modified in patients with progressive supranuclear palsy and striatal degeneration.
(2) Achilles tendon overuse injuries exist as a spectrum of diseases ranging from inflammation of the paratendinous tissue (paratenonitis), to structural degeneration of the tendon (tendinosis), and finally tendon rupture.
(3) Electroretinographic (ERG), morphometric and biochemical studies on retinas from monkeys or rats reveal that moderate level developmental lead (Pb) exposure produces long-term selective rod deficits and degeneration.
(4) of rats resulted in cell death and terminal degeneration in entorhinal, insular, and posterior cingulate cortices, and in the CA1, CA3 and dentate gyrus sectors of hippocampus.
(5) Certain underlying factors in several types of retinal degeneration are first discussed, followed by characteristics of diabetic maculopathy and of other types of macular degeneration including that due to aging.
(6) Hyperopia was more common in younger persons, but senile cataract, macular degeneration and palpebral dermatochalasis or blepharochalasis were more common in older persons.
(7) Since only a few of these medium sized terminals in any one cluster degenerate after tectal lesions, and none degenerate after cortical lesions, it is suggested that the morphological arrangement of these clusters may permit the convergence of axons from several sources, some of which are unidentified, onto the same dendritic segment.
(8) Age-related macular degeneration (ARMD) is one of the leading causes of severe visual loss in the United States.
(9) Deafferentation of certain brain regions in adult animals results in (1) the disappearance of degenerating axon terminals and (2) in the temporary persistence of vacant postsynaptic sites.
(10) The eye of a patient with age-related macular degeneration was treated with krypton laser photocoagulation and later studied histopathologically.
(11) At hypothyroid patients there is an ADP excess which is degenerated to xanthine, the substrate of xanthine oxidase resulting in toxic anion superoxide and UA.
(12) After 7 days, various stages of sensory hair degeneration could be observed.
(13) I think you're probably right that the accent does degenerate along with Richard.
(14) Optical light, transmission, and scanning electron microscopy were used in investigations of epithelia in the glandular region of the milk cistern and greater lactiferous ducts and yielded the following findings, four and six hours from infection: degeneration and necrosis of epithelial cells, intraepithelial foreign cell infiltration (neutrophilic granulocytes, lymphocytes, macrophages), intra-epithelial oedema and locally delimited epithelial loss.
(15) Meanwhile, in the US, Ellen DeGeneres , who is 56 and came out in the 90s, is still flying the lesbian flag on TV.
(16) Key findings include a progressive degeneration of these cholinergic neurons characterized by the formation of immunoreactively atypical NFT, the loss of intraneuronal lipofuscin, a lack of senile plaque and beta-amyloid deposition within the basal forebrain, and end-stage gliosis without residual extracellular NFT.
(17) Differential degeneration of the lateral microvessels may account for increases in collagen nodule growth and ultimate size.
(18) Ultrastructurally, the atrial myocardial cells in all three patients were hypertrophied, and two patients had evidence of focal cell degeneration; the atrium was markedly dilated, but atrial arrhythmias were not noted.
(19) Pathological consequences of these events include inflammatory neutrophil infiltration, damage to the collagen and mucosal basement membrane, increased capillary permeability, edema, cell degeneration and necrosis.
(20) These tangential fibers are in part the preterminal arborizations of geniculocortical axons, since some of them have been shown to degenerate after geniculate lesions.
Deteriorate
Definition:
(v. t.) To make worse; to make inferior in quality or value; to impair; as, to deteriorate the mind.
(v. i.) To grow worse; to be impaired in quality; to degenerate.
Example Sentences:
(1) It is followed by rapid neurobehavioral deterioration in late infancy or early childhood, a developmental arrest, plateauing, and then either a course of retarded development or continued deterioration.
(2) Hypertensive disorders in pregnancy are frequently accompanied by deteriorated renal functions and by pathological lesions in the glomeruli.
(3) A remarkable deterioration of prognosis with increasing age rises the question whether treatment with cytotoxic drugs should be tried in patients more than 60 years old.
(4) "There is … a risk that the political, trade, and gas frictions with Russia could lead to strong deterioration in economic relations between the two countries, with a significant drop in Ukraine's exports to and imports from Russia.
(5) This suggests that there was a deterioration of the vasoconstrictor response and indicated a possible effect of heat at the receptor or effector level.
(6) Four patients had previously been diverted and the other six were reconstructed because of intractable incontinence or deteriorating renal function.
(7) Finally, these cases support the existence of a therapeutic upper limit for desipramine plasma concentrations, above which clinical deterioration occurs.
(8) In view of the high mortality every clinical deterioration of patients with cirrhosis should alert the physician of the presence of SBP.
(9) The authors present a boy with a sudden onset a large intracranial hematoma causing rapid neurologic deterioration.
(10) The data suggest late hemodynamic deterioration after 48 hours of IABC.
(11) Aspartylglycosaminuria (AGU) is a hereditary metabolic disorder characterized by slowly progressive mental deterioration from infancy, urinary excretion of large amounts of aspartylglycosamine, and decreased activity of the lysosomal enzyme aspartylglcosamine amido hydrolase in various body tissues and fluids.
(12) The dilemma focuses on whether the obliteration or removal of the cystic areas will benefit or cause further deterioration of the patient's condition.
(13) Bacteriuria was not associated with deteriorating renal function determined by serial plasma creatinine estimations.
(14) The deteriorating situation would worsen if ministers pressed ahead with another controversial Lansley policy – that of abolishing the cap on the amount of income semi-independent foundation trust hospitals can make by treating private patients.
(15) During a postoperative follow-up period of 1 to 3 years, no further deterioration has been observed and magnetic resonance studies have demonstrated a space filled with cerebrospinal fluid (CSF) around the lumbosacral cord.
(16) Use of sunglasses that block all ultraviolet radiation and severely attenuate high-energy visible radiation will slow the pace of ocular deterioration and delay the onset of age-related disease, thereby reducing its prevalence.
(17) Sechin warned the west earlier this week that expanding sanctions over Russia's annexation of Ukraine's Crimea region would only make the political situation deteriorate further, according to Reuters.
(18) Rates of clinical deterioration and frequencies of attacks were not significantly different between treated and control groups.
(19) In a follow-up of 17 HIV-positive subjects, nine presented deteriorated reflexes in the tests and higher IgG immune complex levels.
(20) However, these good results deteriorated on longer follow-up and were not expected to be permanent.