(n.) The act or state of growing worse, or the state of having become worse; decline; degradation; debasement; degeneracy; deterioration.
(n.) That condition of a tissue or an organ in which its vitality has become either diminished or perverted; a substitution of a lower for a higher form of structure; as, fatty degeneration of the liver.
(n.) A gradual deterioration, from natural causes, of any class of animals or plants or any particular organ or organs; hereditary degradation of type.
(n.) The thing degenerated.
Example Sentences:
(1) Thus, our results indicate that calbindin-D28k is a useful marker for the projection system from the matrix compartment and that its expression is modified in patients with progressive supranuclear palsy and striatal degeneration.
(2) Achilles tendon overuse injuries exist as a spectrum of diseases ranging from inflammation of the paratendinous tissue (paratenonitis), to structural degeneration of the tendon (tendinosis), and finally tendon rupture.
(3) Electroretinographic (ERG), morphometric and biochemical studies on retinas from monkeys or rats reveal that moderate level developmental lead (Pb) exposure produces long-term selective rod deficits and degeneration.
(4) of rats resulted in cell death and terminal degeneration in entorhinal, insular, and posterior cingulate cortices, and in the CA1, CA3 and dentate gyrus sectors of hippocampus.
(5) Certain underlying factors in several types of retinal degeneration are first discussed, followed by characteristics of diabetic maculopathy and of other types of macular degeneration including that due to aging.
(6) Hyperopia was more common in younger persons, but senile cataract, macular degeneration and palpebral dermatochalasis or blepharochalasis were more common in older persons.
(7) Since only a few of these medium sized terminals in any one cluster degenerate after tectal lesions, and none degenerate after cortical lesions, it is suggested that the morphological arrangement of these clusters may permit the convergence of axons from several sources, some of which are unidentified, onto the same dendritic segment.
(8) Age-related macular degeneration (ARMD) is one of the leading causes of severe visual loss in the United States.
(9) Deafferentation of certain brain regions in adult animals results in (1) the disappearance of degenerating axon terminals and (2) in the temporary persistence of vacant postsynaptic sites.
(10) The eye of a patient with age-related macular degeneration was treated with krypton laser photocoagulation and later studied histopathologically.
(11) At hypothyroid patients there is an ADP excess which is degenerated to xanthine, the substrate of xanthine oxidase resulting in toxic anion superoxide and UA.
(12) After 7 days, various stages of sensory hair degeneration could be observed.
(13) I think you're probably right that the accent does degenerate along with Richard.
(14) Optical light, transmission, and scanning electron microscopy were used in investigations of epithelia in the glandular region of the milk cistern and greater lactiferous ducts and yielded the following findings, four and six hours from infection: degeneration and necrosis of epithelial cells, intraepithelial foreign cell infiltration (neutrophilic granulocytes, lymphocytes, macrophages), intra-epithelial oedema and locally delimited epithelial loss.
(15) Meanwhile, in the US, Ellen DeGeneres , who is 56 and came out in the 90s, is still flying the lesbian flag on TV.
(16) Key findings include a progressive degeneration of these cholinergic neurons characterized by the formation of immunoreactively atypical NFT, the loss of intraneuronal lipofuscin, a lack of senile plaque and beta-amyloid deposition within the basal forebrain, and end-stage gliosis without residual extracellular NFT.
(17) Differential degeneration of the lateral microvessels may account for increases in collagen nodule growth and ultimate size.
(18) Ultrastructurally, the atrial myocardial cells in all three patients were hypertrophied, and two patients had evidence of focal cell degeneration; the atrium was markedly dilated, but atrial arrhythmias were not noted.
(19) Pathological consequences of these events include inflammatory neutrophil infiltration, damage to the collagen and mucosal basement membrane, increased capillary permeability, edema, cell degeneration and necrosis.
(20) These tangential fibers are in part the preterminal arborizations of geniculocortical axons, since some of them have been shown to degenerate after geniculate lesions.
Degenerative
Definition:
(a.) Undergoing or producing degeneration; tending to degenerate.
Example Sentences:
(1) Nutritional factors or environmental toxins have important effects on CNS degenerative changes.
(2) Compared with conservative management, better long-term success (determined by return of athletic soundness and less evidence of degenerative joint disease) was achieved with surgical curettage of elbow subchondral cystic lesions.
(3) The earliest degenerative changes were seen in sensory and motor terminals at 20-24 h after the lesion.
(4) Apparently these two degenerative macular conditions are different.
(5) It is also suggested that degenerative changes occur in the dentate gyrus and may be involved in the delayed neural death of CA1 pyramidal cells.
(6) Interphase death thus involves a discrete, abrupt transition from the normal state and is not merely the consequence of progressive and degenerative changes.
(7) Pathological changes may, thus, be initially confined to projecting and intrinsic neurons localized in cortical and subcortical olfactory structures; arguments are advanced which favor the view that excitotoxic phenomena could be mainly responsible for the overall degenerative picture.
(8) Structurally altered polymorphic variants with reduced activity, such as tetrameric interface mutant Ile-58 to Thr, may produce not only an early selective advantage, through enhanced cytotoxicity of tumor necrosis factor for virus-infected cells, but also detrimental effects from increased mitochondrial oxidative damage, contributing to degenerative conditions, including diabetes, aging, and Parkinson's and Alzheimer's diseases.
(9) Gyrate atrophy is a hereditary chorioretinal degenerative disease caused by a deficiency of the mitochondrial enzyme, ornithine aminotransferase (OAT).
(10) The correlation of posterior intervertebral (facet) joint tropism (asymmetry), degenerative facet disease, and intervertebral disc disease was reviewed in a retrospective study of magnetic resonance images of the lumbar spine from 100 patients with complaints of low back pain and sciatica.
(11) This may help explain the poor correlation of low-back pain with radiographic degenerative changes reported in previous epidemiologic studies.
(12) Hypermobility and instability following injury and degenerative joint disease is poorly understood and often not recognized as the cause of the patients symptoms.
(13) Lumbosacral spine films revealed only minimal degenerative changes, while lumbar myelogram showed L4-L5 and L5-S1 ventral extradural defects.
(14) Indications for this procedure are discussed in relation to injuries and tumoral, degenerative and malformatory lesions.
(15) Prions are novel, transmissible pathogens causing degenerative diseases of the central nervous system both in humans and in animals.
(16) This is believed to be the first reported case of degenerative cardiomyopathy in a captive marsupial in Nigeria.
(17) Nonoperative treatment in the adult patient has been shown to accelerate degenerative arthritis, which involves all 3 compartments of the knee.
(18) Fetal cortical tissue, implanted into the neuron-depleted cortex in the form of a dissociated cell suspension, completely prevented this degenerative change of the basal nucleus cholinergic neurons.
(19) The described method is concluded to give alterations in the temporomandibular tissues, as seen in degenerative joint disease of an early stage.
(20) CT possesses some advantages over roentgenography in the diagnosis of degenerative vertebral diseases and can be recommended as the principal method together with roentgenography for investigation of patients with lumbar pains.