(n.) The act or state of growing worse, or the state of having become worse; decline; degradation; debasement; degeneracy; deterioration.
(n.) That condition of a tissue or an organ in which its vitality has become either diminished or perverted; a substitution of a lower for a higher form of structure; as, fatty degeneration of the liver.
(n.) A gradual deterioration, from natural causes, of any class of animals or plants or any particular organ or organs; hereditary degradation of type.
(n.) The thing degenerated.
Example Sentences:
(1) Thus, our results indicate that calbindin-D28k is a useful marker for the projection system from the matrix compartment and that its expression is modified in patients with progressive supranuclear palsy and striatal degeneration.
(2) Achilles tendon overuse injuries exist as a spectrum of diseases ranging from inflammation of the paratendinous tissue (paratenonitis), to structural degeneration of the tendon (tendinosis), and finally tendon rupture.
(3) Electroretinographic (ERG), morphometric and biochemical studies on retinas from monkeys or rats reveal that moderate level developmental lead (Pb) exposure produces long-term selective rod deficits and degeneration.
(4) of rats resulted in cell death and terminal degeneration in entorhinal, insular, and posterior cingulate cortices, and in the CA1, CA3 and dentate gyrus sectors of hippocampus.
(5) Certain underlying factors in several types of retinal degeneration are first discussed, followed by characteristics of diabetic maculopathy and of other types of macular degeneration including that due to aging.
(6) Hyperopia was more common in younger persons, but senile cataract, macular degeneration and palpebral dermatochalasis or blepharochalasis were more common in older persons.
(7) Since only a few of these medium sized terminals in any one cluster degenerate after tectal lesions, and none degenerate after cortical lesions, it is suggested that the morphological arrangement of these clusters may permit the convergence of axons from several sources, some of which are unidentified, onto the same dendritic segment.
(8) Age-related macular degeneration (ARMD) is one of the leading causes of severe visual loss in the United States.
(9) Deafferentation of certain brain regions in adult animals results in (1) the disappearance of degenerating axon terminals and (2) in the temporary persistence of vacant postsynaptic sites.
(10) The eye of a patient with age-related macular degeneration was treated with krypton laser photocoagulation and later studied histopathologically.
(11) At hypothyroid patients there is an ADP excess which is degenerated to xanthine, the substrate of xanthine oxidase resulting in toxic anion superoxide and UA.
(12) After 7 days, various stages of sensory hair degeneration could be observed.
(13) I think you're probably right that the accent does degenerate along with Richard.
(14) Optical light, transmission, and scanning electron microscopy were used in investigations of epithelia in the glandular region of the milk cistern and greater lactiferous ducts and yielded the following findings, four and six hours from infection: degeneration and necrosis of epithelial cells, intraepithelial foreign cell infiltration (neutrophilic granulocytes, lymphocytes, macrophages), intra-epithelial oedema and locally delimited epithelial loss.
(15) Meanwhile, in the US, Ellen DeGeneres , who is 56 and came out in the 90s, is still flying the lesbian flag on TV.
(16) Key findings include a progressive degeneration of these cholinergic neurons characterized by the formation of immunoreactively atypical NFT, the loss of intraneuronal lipofuscin, a lack of senile plaque and beta-amyloid deposition within the basal forebrain, and end-stage gliosis without residual extracellular NFT.
(17) Differential degeneration of the lateral microvessels may account for increases in collagen nodule growth and ultimate size.
(18) Ultrastructurally, the atrial myocardial cells in all three patients were hypertrophied, and two patients had evidence of focal cell degeneration; the atrium was markedly dilated, but atrial arrhythmias were not noted.
(19) Pathological consequences of these events include inflammatory neutrophil infiltration, damage to the collagen and mucosal basement membrane, increased capillary permeability, edema, cell degeneration and necrosis.
(20) These tangential fibers are in part the preterminal arborizations of geniculocortical axons, since some of them have been shown to degenerate after geniculate lesions.
Regeneration
Definition:
(n.) The act of regenerating, or the state of being regenerated.
(n.) The entering into a new spiritual life; the act of becoming, or of being made, Christian; that change by which holy affectations and purposes are substituted for the opposite motives in the heart.
(n.) The reproduction of a part which has been removed or destroyed; re-formation; -- a process especially characteristic of a many of the lower animals; as, the regeneration of lost feelers, limbs, and claws by spiders and crabs.
(n.) The reproduction or renewal of tissues, cells, etc., which have been used up and destroyed by the ordinary processes of life; as, the continual regeneration of the epithelial cells of the body, or the regeneration of the contractile substance of muscle.
(n.) The union of parts which have been severed, so that they become anatomically perfect; as, the regeneration of a nerve.
Example Sentences:
(1) Elements in the skin therefore seemed to enhance nerve regeneration and function.
(2) Together these observations suggest that cytotactin is an endogenous cell surface modulatory protein and provide a possible mechanism whereby cytotactin may contribute to pattern formation during development, regeneration, tumorigenesis, and wound healing.
(3) The present study was done in order to document the ability of the eighth cranial nerve of the bullfrog (Rana catesbeiana) to regenerate, the anatomic characteristics of the regenerated fibers, and the specificity of projections from individual endorgan branches of the nerve.
(4) The data indicate that adult neurons with an intrinsic ability to regenerate axons can respond to substances with neurotrophic or neurite-promoting activities in tissue cultures.
(5) Polypeptide factor isolated from vascular wall of the cattle ("vasonin") was shown to affect the immunogenesis and hemostasis, to stimulate kallikrein-kinin system and to accelerate processes of regeneration.
(6) Endogeneous satellite cells in skeletal muscle regenerating from bupivacaine damage were infected with an injected retrovirus containing the Escherichia coli beta-galactosidase gene under the promoter control of the Moloney murine leukemia virus long-terminal repeat.
(7) Electron microscopic radioautography is considered as the most adequate method for studying intracellular regeneration.
(8) Axonal regeneration with the ANG was equal to SAGs as measured by axonal diameters, physiological, and functional methods, although the SAG demonstrated statistically higher axonal counts.
(9) As an extension of the previous study which indicated that mesoglea is a primitive basement membrane which has retained some characteristics of interstitial extracellular matrix, the present study was undertaken to analyze the role of mesoglea components during head regeneration in Hydra vulgaris.
(10) These data show that liver regeneration is accompanied by a significant increase in fasting putrescine and spermidine concentrations, which might be biochemical signals of active liver cell regeneration.
(11) Roger Madelin, the chief executive of the developers Argent, which consulted the prince's aides on the £2bn plan to regenerate 27 hectares (67 acres) of disused rail land at Kings Cross in London, said the prince now has a similar stature as a consultee as statutory bodies including English Heritage, the Commission for Architecture and the Built Environment and professional bodies including Riba and the Royal Institute of Chartered Surveyors.
(12) There was a greater chance for the regeneration of a connective tissue attachment in nongrafted intrabony defects than in grafted defects; new cellular cementum formed equally well on old cementum, dentin, or both old cementum and dentin in the same defect.
(13) The authors are of the opinion that the processes occurring in the neighbourhood of the traumatic skin wound can be influenced and that regeneration can be regulated.
(14) The proliferating cells showing increased hybridization include normal mitotically active crypt epithelium, regenerating epithelium in ulcerative colitis, adenomatous epithelium, and adenocarcinomatous epithelium.
(15) Between the 3rd and 4th week following amputation, the first fully differentiated striated muscle cells appear, and in the 6th week myogenic differentiation extends throughout the regenerate.
(16) Results suggest that nerve regeneration through an autogenous graft is significantly improved by local treatment with triamcinolone acetonide.
(17) Contribution of proliferation and hypertrophy of the epitheliocytes to the growth and regeneration of the rat parathyroid glands was estimated using organo- and cytometry, cytophotometry of DNA content in the nuclei and determination of mitotic index.
(18) Air-regenerated monomers of bovine seminal ribonuclease have been found capable of reassociating into native dimers, whereas monomers refolded in the presence of a glutathione redox mixture do not reassociate into dimers [Smith, K. G., D'Alessio, G. and Schaffer, S. W. (1978) Biochemistry 17, 2633-2638].
(19) Enhanced regeneration with apoptosis and lysis of the symplasmic nuclei is observed between Day 14 and Day 16.
(20) CoQ10 suppressed the mentioned phenomenon in regenerating liver.