(a.) Undergoing or producing degeneration; tending to degenerate.
Example Sentences:
(1) Nutritional factors or environmental toxins have important effects on CNS degenerative changes.
(2) Compared with conservative management, better long-term success (determined by return of athletic soundness and less evidence of degenerative joint disease) was achieved with surgical curettage of elbow subchondral cystic lesions.
(3) The earliest degenerative changes were seen in sensory and motor terminals at 20-24 h after the lesion.
(4) Apparently these two degenerative macular conditions are different.
(5) It is also suggested that degenerative changes occur in the dentate gyrus and may be involved in the delayed neural death of CA1 pyramidal cells.
(6) Interphase death thus involves a discrete, abrupt transition from the normal state and is not merely the consequence of progressive and degenerative changes.
(7) Pathological changes may, thus, be initially confined to projecting and intrinsic neurons localized in cortical and subcortical olfactory structures; arguments are advanced which favor the view that excitotoxic phenomena could be mainly responsible for the overall degenerative picture.
(8) Structurally altered polymorphic variants with reduced activity, such as tetrameric interface mutant Ile-58 to Thr, may produce not only an early selective advantage, through enhanced cytotoxicity of tumor necrosis factor for virus-infected cells, but also detrimental effects from increased mitochondrial oxidative damage, contributing to degenerative conditions, including diabetes, aging, and Parkinson's and Alzheimer's diseases.
(9) Gyrate atrophy is a hereditary chorioretinal degenerative disease caused by a deficiency of the mitochondrial enzyme, ornithine aminotransferase (OAT).
(10) The correlation of posterior intervertebral (facet) joint tropism (asymmetry), degenerative facet disease, and intervertebral disc disease was reviewed in a retrospective study of magnetic resonance images of the lumbar spine from 100 patients with complaints of low back pain and sciatica.
(11) This may help explain the poor correlation of low-back pain with radiographic degenerative changes reported in previous epidemiologic studies.
(12) Hypermobility and instability following injury and degenerative joint disease is poorly understood and often not recognized as the cause of the patients symptoms.
(13) Lumbosacral spine films revealed only minimal degenerative changes, while lumbar myelogram showed L4-L5 and L5-S1 ventral extradural defects.
(14) Indications for this procedure are discussed in relation to injuries and tumoral, degenerative and malformatory lesions.
(15) Prions are novel, transmissible pathogens causing degenerative diseases of the central nervous system both in humans and in animals.
(16) This is believed to be the first reported case of degenerative cardiomyopathy in a captive marsupial in Nigeria.
(17) Nonoperative treatment in the adult patient has been shown to accelerate degenerative arthritis, which involves all 3 compartments of the knee.
(18) Fetal cortical tissue, implanted into the neuron-depleted cortex in the form of a dissociated cell suspension, completely prevented this degenerative change of the basal nucleus cholinergic neurons.
(19) The described method is concluded to give alterations in the temporomandibular tissues, as seen in degenerative joint disease of an early stage.
(20) CT possesses some advantages over roentgenography in the diagnosis of degenerative vertebral diseases and can be recommended as the principal method together with roentgenography for investigation of patients with lumbar pains.
Generative
Definition:
(a.) Having the power of generating, propagating, originating, or producing.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(3) Structure assignment of the isomeric immonium ions 5 and 6, generated via FAB from N-isobutyl glycine and N-methyl valine, can be achieved by their collision induced dissociation characteristics.
(4) Richard Bull Woodbridge, Suffolk • Why does Britain need Chinese money to build a new atomic generator ( Letters , 20 October)?
(5) These membrane perturbation effects not observed with bleomycin-iron in the presence of a hydroxyl radical scavenger, dimethyl thiourea, or a chelating agent, desferrioxamine, were correlated with the ability of the complex to generate highly reactive oxygen species.
(6) It was also found that lipocortin I and ONO-RS-082, but not neomycin, facilitated the generation of GIF-producing T cells.
(7) Reactive metabolites which suppress splenic humoral immune responses are thought to be generated within the spleen rather than in distant tissues.
(8) The results indicate that OA-bearing macrophages primed T cells and generated helper T cells, whereas the culture of normal lymphocytes with soluble OA in the absence of macrophages generated suppressor T cells.
(9) Discrimination errors were used to generate a matrix of interletter and interpattern similarities.
(10) The presently available data allow us to draw the following conclusions: 1) G proteins play a mediatory role in the transmission of the signal(s) generated upon receptor occupancy that leads to the observed cytoskeletal changes.
(11) The present study was designed to test the hypothesis that the decreased Epi response following ET was due to 1) depletion of adrenal Epi content such that adrenomedullary stimulation would not release Epi, 2) decreased Epi release with direct stimulation, i.e., desensitization of release, or 3) decreased afferent signals generated by ET itself.
(12) This result suggests that tryptophan-86 may be importantly involved in the generation of the product excited state during aequorin bioluminescence.
(13) Midtrimester abortion by the dilatation and evacuation (D&E) method has generated controversy among health care providers; many authorities insist that this procedure should be performed only by a small group of experts.
(14) The transmission of alcoholism and its effects are thereby lessened for future generations of children of alcoholics.
(15) Furthermore, high-density catalase-positive--but not catalase-negative--E. coli can survive and multiply in the presence of competitive, peroxide-generating streptococci.
(16) We are the generation who saw the war,, who ate bread received with ration cards.
(17) These results suggest that CD4+ protective T cells generated by immunization with vBCG are characterized by the ability to produce IFN-gamma after stimulation with specific Ag.
(18) The alpha-ketoglutarate generated is reduced with glutamate dehydrogenase and NADH.
(19) We investigated the possible contribution made by oropharyngeal microfloral fermentation of ingested carbohydrate to the generation of the early, transient exhaled breath hydrogen rise seen after carbohydrate ingestion.
(20) Extensive proliferation has been shown to accompany the de novo generation of LAK cytotoxicity.