(a.) Undergoing or producing degeneration; tending to degenerate.
Example Sentences:
(1) Nutritional factors or environmental toxins have important effects on CNS degenerative changes.
(2) Compared with conservative management, better long-term success (determined by return of athletic soundness and less evidence of degenerative joint disease) was achieved with surgical curettage of elbow subchondral cystic lesions.
(3) The earliest degenerative changes were seen in sensory and motor terminals at 20-24 h after the lesion.
(4) Apparently these two degenerative macular conditions are different.
(5) It is also suggested that degenerative changes occur in the dentate gyrus and may be involved in the delayed neural death of CA1 pyramidal cells.
(6) Interphase death thus involves a discrete, abrupt transition from the normal state and is not merely the consequence of progressive and degenerative changes.
(7) Pathological changes may, thus, be initially confined to projecting and intrinsic neurons localized in cortical and subcortical olfactory structures; arguments are advanced which favor the view that excitotoxic phenomena could be mainly responsible for the overall degenerative picture.
(8) Structurally altered polymorphic variants with reduced activity, such as tetrameric interface mutant Ile-58 to Thr, may produce not only an early selective advantage, through enhanced cytotoxicity of tumor necrosis factor for virus-infected cells, but also detrimental effects from increased mitochondrial oxidative damage, contributing to degenerative conditions, including diabetes, aging, and Parkinson's and Alzheimer's diseases.
(9) Gyrate atrophy is a hereditary chorioretinal degenerative disease caused by a deficiency of the mitochondrial enzyme, ornithine aminotransferase (OAT).
(10) The correlation of posterior intervertebral (facet) joint tropism (asymmetry), degenerative facet disease, and intervertebral disc disease was reviewed in a retrospective study of magnetic resonance images of the lumbar spine from 100 patients with complaints of low back pain and sciatica.
(11) This may help explain the poor correlation of low-back pain with radiographic degenerative changes reported in previous epidemiologic studies.
(12) Hypermobility and instability following injury and degenerative joint disease is poorly understood and often not recognized as the cause of the patients symptoms.
(13) Lumbosacral spine films revealed only minimal degenerative changes, while lumbar myelogram showed L4-L5 and L5-S1 ventral extradural defects.
(14) Indications for this procedure are discussed in relation to injuries and tumoral, degenerative and malformatory lesions.
(15) Prions are novel, transmissible pathogens causing degenerative diseases of the central nervous system both in humans and in animals.
(16) This is believed to be the first reported case of degenerative cardiomyopathy in a captive marsupial in Nigeria.
(17) Nonoperative treatment in the adult patient has been shown to accelerate degenerative arthritis, which involves all 3 compartments of the knee.
(18) Fetal cortical tissue, implanted into the neuron-depleted cortex in the form of a dissociated cell suspension, completely prevented this degenerative change of the basal nucleus cholinergic neurons.
(19) The described method is concluded to give alterations in the temporomandibular tissues, as seen in degenerative joint disease of an early stage.
(20) CT possesses some advantages over roentgenography in the diagnosis of degenerative vertebral diseases and can be recommended as the principal method together with roentgenography for investigation of patients with lumbar pains.
Regenerative
Definition:
(a.) Of or pertaining to regeneration; tending to regenerate; as, regenerative influences.
Example Sentences:
(1) In this study we investigated the recovery or regenerative process of nasal mucosa in rabbits after mechanical injury on the basis of ultrastructural as well as functional observations.
(2) It was concluded from this that treatment with gangliosides stimulated the regenerative potential of the damaged nerves.
(3) By this action, oxytocin is believed to increase the probability of successful regenerative spikes and thereby initiate electrical activity in quiescent preparations, increase the frequency of burst discharges, the number of spikes in each burst, and the amplitude of spikes in individual cells.
(4) This study demonstrates that a second classical neurotransmitter, dopamine, can act to suppress regenerative neurite outgrowth.
(5) It is concluded that a number of mechanisms can account for the conduction failure resulting from phospholipase A2, including disruption of sodium channels needed for propagation of regenerative nerve impulses and the depletion of high energy phosphates needed to maintain ionic gradients.
(6) These data suggest that the mechanism by which gonadal steroids act in the injured nervous system is partly through the differential regulation of the regenerative properties of the injured cell, presumably via hormone receptor-mediated action at the level of the neuronal genome.
(7) These surplus chromophores become esterified and are temporarily taken up by the pigment epithelium to be re-entered into the visual cycle as fast as they can be processed by the regenerative machinery of the rod outer segments.
(8) We believe that this method may prove to be as beneficial to other investigators who are using experimental peripheral nerve lesions to study the regenerative aspects of the nervous system.
(9) Diethylnitrosoamine is found to alter the course of the regenerative processes induced by partial hepatectomy, which is manifested in essentially other, than in the control, changes of polyribosomes and mRNA.
(10) It is planned to employ this method (after further improvements) in investigating the possible effects of changes in the crevicular fluid composition on the developmental and regenerative processes in the juvenile periodontium.
(11) In both treatments, the proximal axon stumps exhibited regenerative growth as early as 1 day after axotomy, and, by the third day, neurites had extended.
(12) The sustained regenerative responses are considered intriguing and may have relevance both for head-injured humans and for future studies of central nervous system regeneration.
(13) The regenerative response of myelinated axons of the mammalian central nervous system was investigated by inserting peripheral nerve grafts in the vicinity of traumatized rat optic axons.
(14) The hypothetical pattern is regenerative and shows how epithelial cell patterns where cells divide might arise.
(15) After amputation, limbs of both early and late stages form a regenerative blastema and support lens formation from the outer cornea.
(16) This calculation shows a regenerative process during the treatment with the high dose.
(17) Explant exposure to lymphokine was shown by light and electron microscopy to significantly suppress chondrocyte glycosaminoglycan regenerative capacity.
(18) CCl4-induced serum enzyme elevations were significantly lower in 2 days post-PH (PH2) rats when compared to SH rats or 7 days post-PH (PH7) rats maintained on CD diet, indicating that CD potentiated CCl4 hepatotoxicity is significantly reduced in livers stimulated for regenerative activity by PH.
(19) Review of the FNA smears showed the findings to be more typical of a reparative or regenerative process; these findings had been cytologically overinterpreted, partly due to the lack of adequate clinical information submitted with the aspirate.
(20) From this point of view, the appearance of "myasthenic" synapses may be considered as a result of the proceding destructive-regenerative process.