(n.) The act of reducing in rank, character, or reputation, or of abasing; a lowering from one's standing or rank in office or society; diminution; as, the degradation of a peer, a knight, a general, or a bishop.
(n.) The state of being reduced in rank, character, or reputation; baseness; moral, physical, or intellectual degeneracy; disgrace; abasement; debasement.
(n.) Diminution or reduction of strength, efficacy, or value; degeneration; deterioration.
(n.) A gradual wearing down or wasting, as of rocks and banks, by the action of water, frost etc.
(n.) The state or condition of a species or group which exhibits degraded forms; degeneration.
(n.) Arrest of development, or degeneration of any organ, or of the body as a whole.
Example Sentences:
(1) This bone could not be degraded by human monocytes in vitro as well as control bone (only 54% of control; P less than 0.003).
(2) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) At the highest dose of chloroquine tested (500 microM), a slightly greater increase in insulin binding and a decrease in insulin degradation were observed in fetal cells as compared with adult cells.
(5) Addition of extracellular mevalonate led to a concentration-dependent fall in both processes, although a higher concentration was required to produce the same effect on LDL degradation as on HMG-CoA reductase activity.
(6) Radioiodinated a-factor was used to identify the a-factor-degrading activity, which is cell associated, endoproteolytic, and not required for response to pheromone.
(7) Densitometric analysis of myofibrillar proteins separated with sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that troponin I and troponin T were degraded during 60 minutes of CGI.
(8) In addition, we found apyrase activity (which degrades ATP and ADP to AMP and orthophosphate) and an anticoagulant.
(9) Degradation of both viral and host DNA with micrococcal nuclease and spleen phosphodiesterase indicated that CdG was incorporated primarily into internal positions in both DNAs.
(10) In vitro studies showed that BOF-A2 was rapidly degraded to EM-FU and CNDP in homogenates of the liver and small intestine of mice and rats, and in sera of mice, rats and human, and the conversion of EM-FU to 5-FU occurred only in the microsomal fraction of rat liver in the presence of NADPH.
(11) Only PPACK completely inhibited changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin.
(12) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(13) When cultures were pulse labeled for 15 min and then incubated under chase conditions for 105 min, the amount of degraded collagen attained a value equal to approximately 20% of the amount synthesized during the labeling period; the data were fit with a simple exponential function that had a 40-min rise time and a 12-min lag time.
(14) The mode of ribosome degradation under this condition is discussed in terms of differential appearance of these intermediate particles.
(15) Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not.
(16) The resistance of GSA 65 to proteolytic degradation, together with previous immunofluorescence data that indicate the antigen is an integral part of the G. lamblia cyst wall, suggests that this molecule may play a role in maintaining the integrity of the cyst in vivo.
(17) 5% of the degradation resulted from enzymatic activity in the culture medium, presumably due to secretion of proteolytic enzymes by the cells.
(18) At 37 degrees C, 125I-labeled TNF-alpha was rapidly internalized and degraded in L-929, U-937 and LAK cells.
(19) Recovery after EEDQ administration showed that both receptor production rate and degradation rate constants of anterior pituitary D2 and striatal D1 receptors were slowed after chronic estradiol treatment, whereas recovery rates for striatal D2 dopamine receptors were unaffected.
(20) The specific rates of degradation of L-arginine-AMC, gly-proline-AMC, N-alpha-benzoyl-L-arginine-AMC and N-[p-toluene-sulphonyl]gly-pro-arginine-AMC were significantly greater in that group, indicating that the composition of their gingival crevicular fluid was different from that of the gingivitis group.
Dishonor
Definition:
(n.) Lack of honor; disgrace; ignominy; shame; reproach.
(n.) The nonpayment or nonacceptance of commercial paper by the party on whom it is drawn.
(v. t.) To deprive of honor; to disgrace; to bring reproach or shame on; to treat with indignity, or as unworthy in the sight of others; to stain the character of; to lessen the reputation of; as, the duelist dishonors himself to maintain his honor.
(v. t.) To violate the chastity of; to debauch.
(v. t.) To refuse or decline to accept or pay; -- said of a bill, check, note, or draft which is due or presented; as, to dishonor a bill exchange.
Example Sentences:
(1) To test this hypothesis, twin concordance for dishonorable discharge from the US military was examined among 15,924 twin pairs in the National Academy of Sciences-National Research Council (NAS-NRC) Twin Registry, all of whom served in the US military.
(2) I won’t play politics with national security or dishonor the memory of those who we lost.” The former secretary of state referenced the repeated investigations of her husband’s White House in the 1990s by noting “I won’t pretend that this is anything other than what it is: the same old partisan games we’ve seen so many times before.” Yet the night wasn’t just about Clinton’s email scandals.
(3) But we would dishonor those heroes as well to suggest that the work of this nation is somehow complete.
(4) David Brooks, a columnist for the New York Times, wrote last week of the Republican leadership: “There comes a time when neutrality and laying low become dishonorable.
(5) Dishonored 2 (PS4, Xbox One & PC) is shaping up to be one of the highlights of 2016, its spellcheck-defying American-English name the only dubious thing about it.
(6) "I can see a misconduct discharge, but not a dishonorable," Coombs says.
(7) Here's a summary of where things stand: • Manning was sentenced to 35 years in prison minus time served and is to be dishonorably discharged from the military.
(8) And where we reject others simply because of the adults they choose to love, we aren't only dishonoring our fellow citizens, we are betraying the most crucial of all conservative values – individual liberty.
(9) At least one branch of the US government has declared its treatment of the Great Sioux Reservation a blight on America’s past, when, in 1975, a federal court concluded that “a more ripe and rank case of dishonorable dealings will never, in all probability, be found in our history”.
(10) PFC Bradley E. Manning, this court sentences you to be reduced to the grade of Private E1, to forfeit all pay and allowances, to be confined for 35 years and to be dishonorably discharged from the service.
(11) But Stevens dismissed this: “The guy who is running second saying I think it’s dishonorable to win in overtime … Real men don’t kick field goals.” In 1924, HL Mencken wrote of that year’s Democratic national convention: “There is something about a national convention that makes it as fascinating as a revival or a hanging.
(12) Coombs says the dishonorable discharge was inappropriate.
(13) Concordances for dishonorable discharge were not confounded by co-diagnoses of alcoholism.
(14) Unlike most action adventures, your choices in the first Dishonored had meaningful consequences, your character’s upgrades and whether or not you used lethal force palpably changing the game’s beautifully realised world.
(15) Women's sexuality and fertility are powerful and polluting, carrying with them the danger of dishonor and needing to be controlled and directed to their 'proper' social ends by men.
(16) When career politicians are obliged to contemplate the cash available for dishonorable votes, or the cash that will be delivered to opponents in the wake of honorable ones, how can any actual idea matter?
(17) The anonymous artists explained their tribute to the NSA whistleblower in a statement , writing: “It would be a dishonor to those memorialized here not to laud those who protect the ideals they fought for, as Edward Snowden has by bringing the NSA’s fourth amendment-violating surveillance programs to light.
(18) To dismiss the magnitude of this progress -- to suggest, as some sometimes do, that little has changed -- that dishonors the courage and the sacrifice of those who paid the price to march in those years.
(19) Concordance rates for dishonorable discharge were significantly greater for MZ vDZ twin pairs.
(20) If I see any violence, then I will remind folks that that dishonors what happened to Trayvon Martin and his family.