(n.) The act of reducing in rank, character, or reputation, or of abasing; a lowering from one's standing or rank in office or society; diminution; as, the degradation of a peer, a knight, a general, or a bishop.
(n.) The state of being reduced in rank, character, or reputation; baseness; moral, physical, or intellectual degeneracy; disgrace; abasement; debasement.
(n.) Diminution or reduction of strength, efficacy, or value; degeneration; deterioration.
(n.) A gradual wearing down or wasting, as of rocks and banks, by the action of water, frost etc.
(n.) The state or condition of a species or group which exhibits degraded forms; degeneration.
(n.) Arrest of development, or degeneration of any organ, or of the body as a whole.
Example Sentences:
(1) This bone could not be degraded by human monocytes in vitro as well as control bone (only 54% of control; P less than 0.003).
(2) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) At the highest dose of chloroquine tested (500 microM), a slightly greater increase in insulin binding and a decrease in insulin degradation were observed in fetal cells as compared with adult cells.
(5) Addition of extracellular mevalonate led to a concentration-dependent fall in both processes, although a higher concentration was required to produce the same effect on LDL degradation as on HMG-CoA reductase activity.
(6) Radioiodinated a-factor was used to identify the a-factor-degrading activity, which is cell associated, endoproteolytic, and not required for response to pheromone.
(7) Densitometric analysis of myofibrillar proteins separated with sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that troponin I and troponin T were degraded during 60 minutes of CGI.
(8) In addition, we found apyrase activity (which degrades ATP and ADP to AMP and orthophosphate) and an anticoagulant.
(9) Degradation of both viral and host DNA with micrococcal nuclease and spleen phosphodiesterase indicated that CdG was incorporated primarily into internal positions in both DNAs.
(10) In vitro studies showed that BOF-A2 was rapidly degraded to EM-FU and CNDP in homogenates of the liver and small intestine of mice and rats, and in sera of mice, rats and human, and the conversion of EM-FU to 5-FU occurred only in the microsomal fraction of rat liver in the presence of NADPH.
(11) Only PPACK completely inhibited changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin.
(12) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(13) When cultures were pulse labeled for 15 min and then incubated under chase conditions for 105 min, the amount of degraded collagen attained a value equal to approximately 20% of the amount synthesized during the labeling period; the data were fit with a simple exponential function that had a 40-min rise time and a 12-min lag time.
(14) The mode of ribosome degradation under this condition is discussed in terms of differential appearance of these intermediate particles.
(15) Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not.
(16) The resistance of GSA 65 to proteolytic degradation, together with previous immunofluorescence data that indicate the antigen is an integral part of the G. lamblia cyst wall, suggests that this molecule may play a role in maintaining the integrity of the cyst in vivo.
(17) 5% of the degradation resulted from enzymatic activity in the culture medium, presumably due to secretion of proteolytic enzymes by the cells.
(18) At 37 degrees C, 125I-labeled TNF-alpha was rapidly internalized and degraded in L-929, U-937 and LAK cells.
(19) Recovery after EEDQ administration showed that both receptor production rate and degradation rate constants of anterior pituitary D2 and striatal D1 receptors were slowed after chronic estradiol treatment, whereas recovery rates for striatal D2 dopamine receptors were unaffected.
(20) The specific rates of degradation of L-arginine-AMC, gly-proline-AMC, N-alpha-benzoyl-L-arginine-AMC and N-[p-toluene-sulphonyl]gly-pro-arginine-AMC were significantly greater in that group, indicating that the composition of their gingival crevicular fluid was different from that of the gingivitis group.
Rank
Definition:
(superl.) Luxuriant in growth; of vigorous growth; exuberant; grown to immoderate height; as, rank grass; rank weeds.
(superl.) Raised to a high degree; violent; extreme; gross; utter; as, rank heresy.
(superl.) Causing vigorous growth; producing luxuriantly; very rich and fertile; as, rank land.
(superl.) Strong-scented; rancid; musty; as, oil of a rank smell; rank-smelling rue.
(superl.) Strong to the taste.
(superl.) Inflamed with venereal appetite.
(adv.) Rankly; stoutly; violently.
(n. & v.) A row or line; a range; an order; a tier; as, a rank of osiers.
(n. & v.) A line of soldiers ranged side by side; -- opposed to file. See 1st File, 1 (a).
(n. & v.) Grade of official standing, as in the army, navy, or nobility; as, the rank of general; the rank of admiral.
(n. & v.) An aggregate of individuals classed together; a permanent social class; an order; a division; as, ranks and orders of men; the highest and the lowest ranks of men, or of other intelligent beings.
(n. & v.) Degree of dignity, eminence, or excellence; position in civil or social life; station; degree; grade; as, a writer of the first rank; a lawyer of high rank.
(n. & v.) Elevated grade or standing; high degree; high social position; distinction; eminence; as, a man of rank.
(v. t.) To place abreast, or in a line.
(v. t.) To range in a particular class, order, or division; to class; also, to dispose methodically; to place in suitable classes or order; to classify.
(v. t.) To take rank of; to outrank.
(v. i.) To be ranged; to be set or disposed, as in a particular degree, class, order, or division.
(v. i.) To have a certain grade or degree of elevation in the orders of civil or military life; to have a certain degree of esteem or consideration; as, he ranks with the first class of poets; he ranks high in public estimation.
Example Sentences:
(1) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
(2) Despite a 10-year deadline to have the same number of ethnic minority officers in the ranks as in the populations they serve, the target was missed and police are thousands of officers short.
(3) Measures of average and cumulative rank were used to augment tests of the significance of correlations between different indicators.
(4) The programs are written in Fortran and are implemented on a Rank Xerox Sigma 6 computer.
(5) Significant differences in the pharmacological characteristics of the alpha 2 adrenoceptor were observed between the tissues with reference to both absolute drug affinities as well as rank order of drug potency.
(6) While superheroes like “superman” (21st in SplashData’s 2014 rankings) and “batman” (24th) may be popular choices for passwords, the results if they are cracked could be anything other than super – and users will only have themselves to blame.
(7) This analysis is based on a ranking of neighbourhoods according to the participation of young people in higher education.
(8) When histamine (5 micrograms) was injected into three different levels of the ventricular system, the magnitude and duration of the resulting increases in plasma epinephrine and glucose were in the following rank order: the third ventricle greater than aqueduct much greater than fourth ventricle.
(9) The rank order of potency of the peptides tested was VIP greater than rat (r) peptide histidine isoleucine = human (h) PHI greater than rGRF greater than bovine GRF = porcine PHI = VIP-(10-28) greater than hGRF greater than secretin greater than apamin greater than glucagon.
(10) In the latter case, the studies have resulted in a ranking of processes and treatment methods to protect the environment.
(11) Cefuzoname seems to be among the middle ranks of beta-lactam agents as far as penetration rate is concerned; however, when its potent antibacterial activity and broad spectrum are taken into account, the concentrations in CSF in patients with meningitis seem worth examining.
(12) They include two leading Republican hopefuls for the presidential race in 2016, Rand Paul and Marco Rubio; three of them enjoy A+ rankings from the NRA and a further eight are listed A. Rand Paul of Kentucky The junior senator's penchant for filibusters became famous during his nearly 13-hour speech against the use unmanned drones, and he is one of three senators who sent an initial missive to Reid , warning him of another verbose round.
(13) Using an explicit process, the Oregon Health Services Commission has completed the ranking of 714 condition-treatment pairs.
(14) Autonomy, sense of accomplishment and time spent in patient care ranked as the top three factors contributing to job satisfaction.
(15) On guinea-pig lung strip the rank order of potency was U-46619 greater than Wy17186 much greater than PGF2 alpha greater than PGE2 and responses to all agonists tested were blocked by AH19437 but not by SC-19220.
(16) In the UK, George Osborne used this to his advantage, claiming "Britain faces the disaster of having its international credit rating downgraded" even after Moody's ranked UK debt as "resilient".
(17) The eight senators, including the incoming ranking member Mark Warner of Virginia, wrote to Barack Obama to request he declassify relevant intelligence on the election.
(18) Hence, a priori haplotyping cannot exclude a particular CF mutation, but in combination with population genetic data, enables mutations to be ranked by decreasing probability.
(19) The rank order of potencies of the four AEDs was: (a) in young: CBZ > PHT > PhB > VPA; (b) in adult: CBZ > PhB > PHT > VPA.
(20) Patients clinically evaluated as effective tended to be so pathologically as well, as shown by Spearman's rank correlation test which gave a significant correlation between the clinical and pathological scores.