(v. t.) To reduce from a higher to a lower rank or degree; to lower in rank; to deprive of office or dignity; to strip of honors; as, to degrade a nobleman, or a general officer.
(v. t.) To reduce in estimation, character, or reputation; to lessen the value of; to lower the physical, moral, or intellectual character of; to debase; to bring shame or contempt upon; to disgrace; as, vice degrades a man.
(v. t.) To reduce in altitude or magnitude, as hills and mountains; to wear down.
(v. i.) To degenerate; to pass from a higher to a lower type of structure; as, a family of plants or animals degrades through this or that genus or group of genera.
Example Sentences:
(1) This bone could not be degraded by human monocytes in vitro as well as control bone (only 54% of control; P less than 0.003).
(2) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) At the highest dose of chloroquine tested (500 microM), a slightly greater increase in insulin binding and a decrease in insulin degradation were observed in fetal cells as compared with adult cells.
(5) Addition of extracellular mevalonate led to a concentration-dependent fall in both processes, although a higher concentration was required to produce the same effect on LDL degradation as on HMG-CoA reductase activity.
(6) Radioiodinated a-factor was used to identify the a-factor-degrading activity, which is cell associated, endoproteolytic, and not required for response to pheromone.
(7) Densitometric analysis of myofibrillar proteins separated with sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that troponin I and troponin T were degraded during 60 minutes of CGI.
(8) In addition, we found apyrase activity (which degrades ATP and ADP to AMP and orthophosphate) and an anticoagulant.
(9) Degradation of both viral and host DNA with micrococcal nuclease and spleen phosphodiesterase indicated that CdG was incorporated primarily into internal positions in both DNAs.
(10) In vitro studies showed that BOF-A2 was rapidly degraded to EM-FU and CNDP in homogenates of the liver and small intestine of mice and rats, and in sera of mice, rats and human, and the conversion of EM-FU to 5-FU occurred only in the microsomal fraction of rat liver in the presence of NADPH.
(11) Only PPACK completely inhibited changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin.
(12) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(13) When cultures were pulse labeled for 15 min and then incubated under chase conditions for 105 min, the amount of degraded collagen attained a value equal to approximately 20% of the amount synthesized during the labeling period; the data were fit with a simple exponential function that had a 40-min rise time and a 12-min lag time.
(14) The mode of ribosome degradation under this condition is discussed in terms of differential appearance of these intermediate particles.
(15) Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not.
(16) The resistance of GSA 65 to proteolytic degradation, together with previous immunofluorescence data that indicate the antigen is an integral part of the G. lamblia cyst wall, suggests that this molecule may play a role in maintaining the integrity of the cyst in vivo.
(17) 5% of the degradation resulted from enzymatic activity in the culture medium, presumably due to secretion of proteolytic enzymes by the cells.
(18) At 37 degrees C, 125I-labeled TNF-alpha was rapidly internalized and degraded in L-929, U-937 and LAK cells.
(19) Recovery after EEDQ administration showed that both receptor production rate and degradation rate constants of anterior pituitary D2 and striatal D1 receptors were slowed after chronic estradiol treatment, whereas recovery rates for striatal D2 dopamine receptors were unaffected.
(20) The specific rates of degradation of L-arginine-AMC, gly-proline-AMC, N-alpha-benzoyl-L-arginine-AMC and N-[p-toluene-sulphonyl]gly-pro-arginine-AMC were significantly greater in that group, indicating that the composition of their gingival crevicular fluid was different from that of the gingivitis group.
Deride
Definition:
(v. t.) To laugh at with contempt; to laugh to scorn; to turn to ridicule or make sport of; to mock; to scoff at.
Example Sentences:
(1) While some might deride the deliberate mainstream branding and design, saying it panders to convention, this is exactly what Hannah feels her community needs.
(2) Trawling through the private telephone conversations of royals, politicians and celebrities in the hope of picking up scandalous gossip is not seen as legitimate news gathering and the techniques of entrapment which led to the recent Pakistani match-fixing scandal , although grudgingly admired in this particular case, are derided as manufacturing the news.
(3) In Catalonia the outspoken local politician is derided as a feeble sellout for opposing total independence; in the rest of Spain he is damned as a rabid separatist for wanting a bit more self-governance.
(4) Though parts of his ¥25tn (£160bn) stimulus package were derided – in particular the cash handouts to all residents – those, together with subsidies for fuel-efficient cars and green electrical appliances, have produced at least some short-term benefits.
(5) Kabila, derided by his opponents as being "Rwandan", came to power in 2001 after the assassination of his father, warlord Laurent Kabila, who had seized power in a coup with Rwandan backing.
(6) Yes, many will deride the protesters as spoilsports.
(7) Her family's privacy has been invaded to find the "causes" of her choice and her personal appearance derided, not least within what might otherwise be called the sisterhood.
(8) The piracy charges have been broadly derided as having little basis in Russian law, partly as it is fairly clear to all involved that Greenpeace's intentions were never to steal or seize property from the Prirazlomnaya rig.
(9) An American claim that biofuels contributed less than 3% to food price rises was widely derided.
(10) After so long being derided, is this disco's revenge?
(11) Hinkley Point power station makes no sense on so many levels Read more The agreement was welcomed by many in Britain’s business community and bytrade unions, but was derided by Greenpeace, which was angry that the deal is going ahead when solar and wind power face major subsidy cuts.
(12) Especially because Trump suggested that he never settled cases and derided others who did settle them.” The looming move to the White House ratcheted up pressure, Tobias said.
(13) Even Trump, who has constantly derided “political correctness”, realised he had gone too far.
(14) The liberals are being derided in Tahrir Square as having sold out to the supreme council of the armed forces (Scaf) by agreeing to participate in a flawed "transition" proceeding at a snail's pace; and outgunned by the organisational firepower of the Islamist parties and remnants of Hosni Mubarak's old ruling NDP, both of which look set to sweep the board when voting stations open their doors on Monday.
(15) Nine years after Jonathan Franzen derided Oprah Winfrey's choice of "schmaltzy, one-dimensional" novels for her book club, becoming the first author to be formally disinvited to appear on her show, these two giants of American cultural life appear to have buried the hatchet.
(16) That has some of his fans worried that Stewart is now, like the reporters he derides, too close to the centre of power.
(17) He has been derided in these pages, but that derision is surpassed by the venomous hatred of the Daily Mail , which loathes the Cameron government in any case and particularly despised Mitchell in his previous job.
(18) It’s just to show solidarity with the Mexican people,” Milne said, “and everyone else that Trump has derided, insulted and intimidated.” Trump has infuriated Mexicans with his comments about immigrants and proposal to build a wall along the United States’ southern border.
(19) In some of the strongest passages, derided as class war by the Conservatives, he claimed Cameron's record had forfeited the right to be regarded as a one nation prime minister.
(20) They were widely derided for being the "Postman Pats" of international terrorism, but the Welsh nationalists' prolific firebombing campaign of holiday cottages begun at the end of the 1970s caused havoc in the rural idyll of the Lleyn peninsula.